Name (Synonyms) | Correlation | |
---|---|---|
drug359 | Convalescent COVID 19 Plasma Wiki | 0.71 |
drug542 | Global Longitudinal Strain Wiki | 0.71 |
drug259 | COVID-19 exposure Wiki | 0.71 |
drug360 | Convalescent Plasma Wiki | 0.21 |
Name (Synonyms) | Correlation | |
---|---|---|
D009202 | Cardiomyopathies NIH | 1.00 |
D002318 | Cardiovascular Diseases NIH | 0.17 |
Name (Synonyms) | Correlation | |
---|---|---|
HP:0001626 | Abnormality of the cardiovascular system HPO | 0.18 |
There are 2 clinical trials
COVID-19 is associated with complications including ARDS and myocardial injury, which informs prognosis and patient outcome. The laboratory plans to perform immunophenotyping of peripheral T-cells in patients with COVID-19 and complications (ARDS, ITU admission, myocardial injury) and map this against clinical patient outcomes. The aim is to determine if there is a specific T-cell immunophenotype associated with COVID-19 and/or complications, which can be used to inform prognosis and potential therapies.
Description: T-cell immunophenotype
Measure: T-cell immunophenotype Time: 12 months from enrollmentDescription: death, survival to discharge
Measure: Mortality Time: 12 months from enrolmentDescription: Admission to the intensive care
Measure: ITU admission Time: 12 months from enrolmentDescription: Defined by troponin rise to >99th centile
Measure: Myocardial injury Time: 12 months from enrolmentThe effects of severe acute respiratory syndrome SARS-Cov-2 (Covid-19) on the myocardium and their role in the clinical course of infected patients are still unknown. Epidemiological studies report biological myocardial involvement in 10 to 25% of cases. The objective of this study is to cardiac phenotype using comprehensive cardiac imaging tools of patients infected with Covid 19 in order to explore the functional impact of the infection on the myocardium.
Description: Left ventricular function evaluated by global longitudinal strain
Measure: Left ventricular function Time: Day 0Description: Left ventricular function evaluated by global longitudinal strain
Measure: Left ventricular function Time: Day 3Description: Left ventricular function evaluated by global longitudinal strain
Measure: Left ventricular function Time: Day 7Description: Cytokine rate
Measure: inflammatory biological parameters Time: Day 0