CovidResearchTrials by Shray Alag


CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)


PTI-125, 100 mg tabletWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (2)


Name (Synonyms) Correlation
drug359 Biosensor Wiki 1.00
drug464 COVID-19 RT-PCR Wiki 0.58

Correlated MeSH Terms (1)


Name (Synonyms) Correlation
D000544 Alzheimer Disease NIH 0.58

Correlated HPO Terms (1)


Name (Synonyms) Correlation
HP:0002511 Alzheimer disease HPO 0.58

There is one clinical trial.

Clinical Trials


1 A 12-Month, Open-Label Safety Study of PTI-125 in Mild-to-moderate Alzheimer's Disease Patients

An Open-label study for patients who completed the previous studies, PTI-125-02 or PTI-125-03. Additional new patients will be included for a total of 100 patients enrolled for this study.

NCT04388254 Alzheimer Disease Drug: PTI-125, 100 mg tablet
MeSH:Alzheimer Disease
HPO:Alzheimer disease

Primary Outcomes

Description: Biomarkers of AD pathology, neurodegeneration and neuroinflammation

Measure: Cerebrospinal fluid P-tau, neurofilament light chain, neurogranin, Total Tau, YKL-40, Abeta42 (pg/mL)

Time: Screening to Month 12


Related HPO nodes (Using clinical trials)