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    HP:0002615: Hypotension

    Developed by Shray Alag, The Harker School
    Sections: Correlations, Clinical Trials, and HPO

    Correlations computed by analyzing all clinical trials.

    Navigate: Clinical Trials and HPO


    Correlated Drug Terms (2)


    Name (Synonyms) Correlation
    drug1824 Lifelight® Data Collect Oxygen Saturation Group Wiki 1.00
    drug1823 Lifelight® Data Collect Blood Pressure Group Wiki 1.00

    Correlated MeSH Terms (2)


    Name (Synonyms) Correlation
    D007022 Hypotension NIH 1.00
    D000860 Hypoxia NIH 0.18

    Correlated HPO Terms (1)


    Name (Synonyms) Correlation
    HP:0012418 Hypoxemia HPO 0.19

    Clinical Trials

    Navigate: Correlations   HPO

    There is one clinical trial.


    1 The Measurement of VItal SIgns by Lifelight® Data Collect Software in comparisON to the Standard of Care in Acutely Unwell Patients - The VISION-Acute Study

    AIM: We propose an innovative approach using Lifelight® smart technology that will enable the continued provision of high level patient care at the same time as reducing pressure on nursing and equipment resources. METHOD : Lifelight® is a computer program ("app") which can be used on smart devices that contain a camera. It is able to measure all of the vital signs by measuring very small changes in skin colour that occur each time the heart beats. This means that it does not need to touch the patient. We believe this could be an effective way of measuring vital signs, especially during the COVID-19 pandemic when prevention of cross-contamination between patients is essential. Patients are also likely to be reassured by a contactless approach. During this study, we will recruit two groups of people who are hospitalised with an acute illness. The first group will be people expected to have abnormal blood oxygen levels such as those with acute respiratory problems including those with COVID-19. The second group will be people expected to have abnormal blood pressure. These Lifelight vital signs will be compared to measurements from standard clinical equipment. The exact number of participants recruited will depend on how quickly the app "learns" and how many of the vital signs collected are outside of the normal range. For the first group of participants, we will use a camera to collect data about the changes in their face and use this to teach the app how to measure blood oxygen level and also to check how well the app measures blood oxygen level, heart rate and respiratory rate. For the second group of participants, we will use a camera to collect data about the changes in their face to check how well the app measures blood pressure and respiratory rate. All of the data will be kept secure and participants will not be able to be identified.

    NCT04589923
    Conditions
    1. Hypertension
    2. Hypoxia
    3. Hypotension
    Interventions
    1. Device: Lifelight® Data Collect Blood Pressure Group
    2. Device: Lifelight® Data Collect Oxygen Saturation Group
    MeSH:Hypotension Hypoxia
    HPO:Hypotension Hypoxemia

    Primary Outcomes

    Description: Train Lifelight® oxygen saturation algorithms with hypoxic individuals.

    Measure: Primary Objective

    Time: 3 months

    Secondary Outcomes

    Description: Measure oxygen saturation using Lifelight® with accuracy closer to +/- 4%.

    Measure: Secondary Objective 1

    Time: 3 months

    Description: Measure heart rate using Lifelight® with accuracy closer to RMSE of 3bpm.

    Measure: Secondary Objective 2

    Time: 3 months

    Description: Measure respiratory rate using Lifelight® with tolerance accuracy closer to 100% of readings within 5 breaths per minute.

    Measure: Secondary Objective 3

    Time: 3 months

    Description: Measure systolic and diastolic blood pressure using Lifelight® with accuracy closer to 5+/- 8mmHg.

    Measure: Secondary Objective 4

    Time: 3 months

    HPO Nodes


    Reports

    Data processed on January 01, 2021.

    An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.

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