|drug353||Açaí palm berry extract - natural product Wiki||0.58|
|drug1707||Interview by psychologists Wiki||0.58|
|D001289||Attention Deficit Disorder with Hyperactivity NIH||1.00|
|D000067877||Autism Spectrum Disorder NIH||0.58|
|D009080||Mucocutaneous Lymph Node Syndrome NIH||0.58|
|D001997||Bronchopulmonary Dysplasia NIH||0.58|
|D014552||Urinary Tract Infections NIH||0.58|
|D004314||Down Syndrome NIH||0.58|
|D000309||Adrenal Insufficiency NIH||0.58|
|D002659||Child Development Disorders, Pervasive NIH||0.41|
|D001321||Autistic Disorder NIH||0.33|
|D020141||Hemostatic Disorders NIH||0.15|
|D001778||Blood Coagulation Disorders NIH||0.15|
|D003141||Communicable Diseases NIH||0.04|
|D045169||Severe Acute Respiratory Syndrome NIH||0.02|
|D018352||Coronavirus Infections NIH||0.02|
|HP:0000729||Autistic behavior HPO||0.67|
There are 3 clinical trials
The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose for children. The primary objective of this study is to evaluate the PK of understudied drugs currently being administered to children per SOC as prescribed by their treating provider.
In response to the coronavirus disease 2019 (covid-19) outbreak, the home confinement of the population ordered by governments in many countries raise questions about its impact on individuals' physical and mental health in the short and longer term. In children, reduced physical activity, changes in lifestyle, disturbances in sleep patterns, lack of in-person contact with peers, poor or inadequate understanding of health risks may be risk factors of anxiety, stress, fatigue, sleep disorders (Brooks et al, 2020; Wang et al, 2020; Sprang et al, 2013). These problematic effects could be modulated by social factors (housing in urban or rural areas, availability of personal space at home, parenting stress, etc.) (Cluver et al, 2020; Liu et al, 2020).
Description: composition, home confinement, change in the environment, personal room at home, screens with internet access, parents' current professional status, teleworking, care, family concerns related to Covid-19, parenting stress, schooling, recurrent complaints.Measure: Interview of the parents : contextual data Time: Baseline
Description: related to education; related to daily family life; related to leisure, related to care (children/adolescents, parents)Measure: Interview of the children/adolescents/ parents : Experience of the confinement in general Time: Baseline
Description: related to education; related to daily family life; related to leisure, related to care (children/adolescents, parents)Measure: Interview of the children/adolescents/ parents : Experience of the confinement in general Time: 1 month
Description: related to education; related to daily family life; related to leisure, related to care (children/adolescents, parents)Measure: Interview of the children/adolescents/ parents : Experience of the confinement in general Time: 3 months
Description: Data relating to disease and management of care. Experience of the referring caregiver.Measure: Interview of the referring caregiver : data relating to disease and management of care Time: 3 months
The aims of the BIBS Study The Brain Imaging in Babies study (BIBS) aims to improve understanding of how a baby's brain develops from before birth, up until 3-4 years of age. Working with children from a variety of backgrounds and communities, the investigators use a combination of state-of-the-art diagnostic tools such as MRI scans alongside traditional behavioural assessments to capture the earliest information on infant brain development. The focus of the BIBS study MRI scanning is a safe way of producing detailed images using strong magnetic fields and radio waves. It does not use X-ray. Along with learning more about brain development in general, the investigators also try to identify features that may in future help predict whether a child will or will not develop traits of conditions such as Autism Spectrum Disorder (ASD) or Attention Deficit Hyperactivity Disorder (ADHD). Long-term, this may help target useful interventions early on, helping children who are most in need. Since COVID-19 arrived in the United Kingdom (U.K.) in 2020, the investigators have been given ethical approval to include testing for this infection in the mothers and children participating in the study. This may provide an opportunity to better understand how mother and baby respond to infections. The investigators particularly welcome mothers who have had a positive COVID-19 test during their pregnancy to join the study.
Data processed on January 01, 2021.
An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.Drug Reports MeSH Reports HPO Reports