Covid 19 Research using Clinical Trials (Home Page)
Report for D001930: Brain Injuries NIH
(Synonyms: Brain Inj, Brain Inju, Brain Injuries, Brain Injuries,, Brain Injuries,)
Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation
Correlated Drug Terms (5)
| Name (Synonyms) | Correlation | |
|---|---|---|
| drug1343 | TDR Wiki | 1.00 |
| drug193 | Blink and Masseter Inhibitory Reflex Wiki | 1.00 |
| drug325 | Clinical Examination Wiki | 1.00 |
| drug1371 | Test PCR Wiki | 1.00 |
| drug115 | Auditory Evoked Potentials (AEP) Wiki | 1.00 |
Correlated MeSH Terms (0)
| Name (Synonyms) | Correlation |
|---|
Correlated HPO Terms (0)
| Name (Synonyms) | Correlation |
|---|
There is one clinical trial.
Clinical Trials
1 Exploring Brain Damages After COVID-19 Infection
Although direct evidence is currently lacking, the high identity between SARS-CoV-1 and SARS-CoV-2 suggests, that the latter viral strain could also infect the Central Nervous System (CNS). Indeed, some cases of SARS-COV2 encephalitis begin to be described and CNS damages are increasingly highlighted in the literature, but still not objectified by imaging and do not allow to explain the entire clinical patterns. We hypothesise that these CNS damages are not always objectified by Magnetic Resonance Imaging (MRI) but could be indirectly observed by a physiological dysfunction of neural conduction in the brainstem. We will explore brainstem disruption through an electrophysiological approach.
NCT04405986 SARS-CoV 2 Procedure: Auditory Evoked Potentials (AEP) Procedure: Blink and Masseter Inhibitory Reflex MeSH:Brain Injuries
Primary Outcomes
Description: Latencies of electrophysiological responses with Auditory Evoked Potentials
Measure: Latency of electrophysiological response Time: Inclusion (T0)Description: Delay of Muscle contraction (Blink reflex)
Measure: Delay of Muscle contraction Time: Inclusion (T0)Description: Delay of silent period while the patient is asked to tighten the jaws (Masseter Inhibitory Reflex)
Measure: Delay of silent period Time: Inclusion (T0)Description: Duration of silent period while the patient is asked to tighten the jaws (Masseter Inhibitory Reflex)
Measure: Duration of silent period Time: Inclusion (T0)Description: Inhibition rate while the patient is asked to tighten the jaws (Masseter Inhibitory Reflex)
Measure: Inhibition rate Time: Inclusion (T0)