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Report for D006948: Hyperkinesis NIH

(Synonyms: Hyperki, Hyperkines, Hyperkinesis)

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (2)


Name (Synonyms) Correlation
drug287 Caption AI Wiki 1.00
drug702 Interview by psychologists Wiki 1.00

Correlated MeSH Terms (5)


Name (Synonyms) Correlation
D000067877 Autism Spectrum Disorder NIH 1.00
D001289 Attention Deficit Disorder with Hyperactivity NIH 1.00
D002659 Child Development Disorders, Pervasive NIH 1.00
D001321 Autistic Disorder NIH 1.00
D004194 Disease NIH 0.38

Correlated HPO Terms (0)


Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials


1 Clinical Evolution and Parenting in Children and Adolescents With Autism Spectrum Disorder or Attention Deficit Hyperactivity Disorder Quarantined Because of Covid-19 Outbreak

In response to the coronavirus disease 2019 (covid-19) outbreak, the home confinement of the population ordered by governments in many countries raise questions about its impact on individuals' physical and mental health in the short and longer term. In children, reduced physical activity, changes in lifestyle, disturbances in sleep patterns, lack of in-person contact with peers, poor or inadequate understanding of health risks may be risk factors of anxiety, stress, fatigue, sleep disorders (Brooks et al, 2020; Wang et al, 2020; Sprang et al, 2013). These problematic effects could be modulated by social factors (housing in urban or rural areas, availability of personal space at home, parenting stress, etc.) (Cluver et al, 2020; Liu et al, 2020).

NCT04416360 Autism Spectrum Disorder Attention-deficit Hyperactivity Disorder Other: Interview by psychologists
MeSH:Hyperkinesis Disease Autistic Disorder Attention Deficit Disorder with Hyperactivity Autism Spectrum Disorder Child Development Disorders, Pervasive
HPO:Attention deficit hyperactivity disorder Autism Autistic behavior Hyperactivity Hyperkinetic movements

Primary Outcomes

Description: composition, home confinement, change in the environment, personal room at home, screens with internet access, parents' current professional status, teleworking, care, family concerns related to Covid-19, parenting stress, schooling, recurrent complaints.

Measure: Interview of the parents : contextual data

Time: Baseline

Description: related to education; related to daily family life; related to leisure, related to care (children/adolescents, parents)

Measure: Interview of the children/adolescents/ parents : Experience of the confinement in general

Time: Baseline

Description: related to education; related to daily family life; related to leisure, related to care (children/adolescents, parents)

Measure: Interview of the children/adolescents/ parents : Experience of the confinement in general

Time: 1 month

Description: related to education; related to daily family life; related to leisure, related to care (children/adolescents, parents)

Measure: Interview of the children/adolescents/ parents : Experience of the confinement in general

Time: 3 months

Description: Data relating to disease and management of care. Experience of the referring caregiver.

Measure: Interview of the referring caregiver : data relating to disease and management of care

Time: 3 months


HPO Nodes


HP:0000752: Hyperactivity
Genes 483
SMC1A MID2 PTCHD1 SARS1 SYNJ1 FMN2 UBE3A CXORF56 TRIP12 FGF12 BCR KCNB1 ASH1L PAH MAPK10 CNTNAP2 PIGC KIF14 YWHAG PWRN1 TRNL1 ZC3H14 SETD5 PSMD12 PRODH NKX2-1 FMR1 OCRL BSCL2 CRBN DPF2 EBP SMARCC2 HCFC1 PDE4D TNIK KCNA2 USP9X STS CNKSR2 ALKBH8 B3GALNT2 RPS20 DPH1 DYNC1I2 NDST1 CUL4B ANK3 HDAC8 CIC PDE4D DCPS TSPAN7 TBX1 NR2F1 ND1 NFIX KMT2A NEUROD2 PRKCG COX2 CLCN4 AASS SIM1 GNAO1 EBP SEMA4A MED12 UFD1 PHIP IL1RAPL1 SATB2 PAK3 CACNA1A GNE C12ORF4 CSNK2A1 CAMTA1 SH2B1 TSHR TRNQ PRNP NDP SIN3A JMJD1C SRPX2 CC2D1A DNM1 CPLX1 IFNG TRIM8 THRB SNORD116-1 MLH1 IPW GABRA5 STAG2 FRMPD4 YME1L1 ZDHHC9 HDC CCBE1 ACSL4 NTRK1 KDM6B WASHC4 TRNS1 DDX3X FGD1 KANSL1 TSC1 CHD2 SOX5 MAP11 SEC24C AFF2 PIGQ SMC1A FBXO31 BCAP31 IGF1 HCN1 GAMT ADNP GABRG2 IQSEC2 METTL23 PUS7 UPF3B PAK3 WARS2 SNORD115-1 CORO1A SHOC2 EP300 HIVEP2 UBTF SYP COMT ADAT3 CRADD SZT2 VPS13A TGFBR2 SLC1A4 GNB5 SPG7 ZNF41 LNPK RERE STS GATA4 MAN1B1 DNM1 STXBP1 SLC25A13 KIF15 DRD5 OPHN1 COX1 ELN AGTR2 TBX1 YWHAG ND5 FGD1 ND4 PIGP MED25 NSUN2 UBA5 CNKSR2 RAI1 ADAT3 MAGEL2 DMD HGSNAT ELN NUS1 RSRC1 WAC CASK CUL4B DNAJC21 ARV1 RREB1 MTOR CC2D1A SPRED1 DEAF1 GCSH MBOAT7 NSDHL STXBP1 DPP6 GABRG2 DDX3X RAI1 SCN8A TECR LMAN2L HERC2 GP1BB JRK TKT CYFIP2 AARS1 MID2 RFC2 PIEZO2 MAPK1 GATAD2B UQCC2 PCDH19 NSUN2 FRMPD4 SHROOM4 NBN SHANK3 ND6 IGF1 EZR GLDC EP300 SLC25A22 ZNF81 RSRC1 CUX2 GABRA2 CXORF56 KCNA1 TRNF MKRN3-AS1 ACTL6B TRAK1 SMPD1 USP7 CLTC PNKP FLI1 PAH SMC3 ALDH5A1 TBX1 CNTNAP2 ARHGEF6 TRIO DHTKD1 SLITRK1 SIN3A CHD7 IL1RAPL1 PPP2R1A ST3GAL3 PIGY PPM1D SHROOM4 LIMK1 TBL2 KIF11 ARF1 SLC1A2 GABRB3 TSHR DYRK1A INPP5E ZSWIM6 SH3KBP1 TAF1 SCN2A YY1 SLC9A7 SETBP1 IKBKG ALG13 HERC2 TRAPPC9 TKT SLC6A8 TMCO1 PTCH1 ACY1 KCNK9 HIRA GNE TAF6 RAI1 GABRA1 MECP2 FOXP1 LIG4 SH2B1 SHANK3 RAD21 GABRB2 GDI1 TBC1D24 GRIA4 CLIP2 MED12 TRAPPC9 KRAS SETD5 NBN NIPBL PLA2G6 SIK1 GRIK2 PCGF2 NRXN1 MED23 DHCR7 CNKSR2 NSDHL GNS AUTS2 ARID2 HSPG2 GRIN2A PANK2 SLC1A4 GABRB3 BMPR1A DHCR7 SGSH MED13L GLUD1 TTI2 MBD5 PMS1 CLCN4 GABRB3 ADSL KCNA2 HOXA2 KDM5B SLC2A1 ADNP ATRX RAI1 MSH6 EEF1A2 HTT EDC3 PGAP1 FLII SPR SLC6A8 NOP56 MKRN3 PIK3CA ATP6V1A CACNA1H PAH CACNA1B DLG3 SCN1B AIMP1 GRIN2D LINS1 HAL EPCAM CHRNA7 BSCL2 NDN DPYD ABCD1 IQSEC2 KRAS SLC45A1 MCTP2 TCF20 C12ORF4 ATRX PRSS12 TSC2 TLK2 PMS2 FBXO11 TSC2 PPP3CA ATP1A1 ATR BCORL1 PNP AFF2 PCNT ARVCF GTF2I FTSJ1 TRNW COX3 ASPM UPF3B CDKL5 PRKAR1A ARG1 SYNGAP1 KMT2A TTI2 TRNH GNAQ CRBN LHCGR FGFR3 CLIP1 TBX1 PUF60 DNAJC12 AP3B2 DHDDS NAGLU RAB39B PTCHD1 TRNS2 MLXIPL USP27X HDAC4 SNRPN TRIO PWAR1 ANK3 STAG2 TSHR POGZ TIMM8A ARX FLCN NPAP1 FRRS1L GABRG2 BAZ1B HNMT TUBB2B FAN1 WWOX POLA1 GATAD2B SCN8A SETBP1 TUSC3 SLC13A5 DRD4 SATB2 DYM OPHN1 ZNF711 PARS2 IQSEC1 APC2 MSH2 NEXMIF NTRK2 MED12 MANBA RUSC2 MED12 GRIN2A PANK2 ARX TNIK PNKP RAB39B MLH3 FOXP1 HUWE1 SCN3A RPS6KA3 CRKL FMR1 MECP2 SEMA3E UBE3A WDR62 SCN1A RERE AMT NECAP1 GTF2IRD1 CREBBP MED12 CLTC TSC1
Protein Mutations 0
SNP 0