There are 14 clinical trials

Clinical Trials

1 Using a Diagnostic Taste Test as a Surrogate Biomarker to Predict Drug Effectiveness in Patients With Depression (MDD)

The study will be looking at whether a taste test device can be used as a diagnostic aid for depression. Taste tests will be carried out before and after first use of an antidepressant (prescribed by the patient's GP) and then again a month later a further taste test will be conducted. The results of these tests will be assessed to see if they correlate with the outcome of validated mood questionnaires carried out at the first and second visits.

NCT03645447 Depression Diagnostic Test: Taste test

MeSH:Depression Depressive Disorder

HPO:Depressivity

2 Getting it Right: Towards Responsible Social Media Use During a Pandemic

The investigators plan to conduct a cross-sectional survey to examine how social media use during COVID-19 relates to: (1) information management, (2) assessment of the situation, and (3) affect.

NCT04305574 Coronavirus Depression Anxiety Stress Behavioral: Use of social media during COVID-19

MeSH:Coronavirus Infections Depression

3 Mental Health of Urban Mothers (MUM) Study: A Multi-center Randomized Controlled Trial

Mental health disorders are common during pregnancy and the postnatal period, and can have serious adverse effects on the well-being of woman and child. Every tenth woman has depressive symptoms and 5% suffer major depression during pregnancy. The consequences for global mental health due to the novel coronavirus disease, COVID-19, are likely to be significant and may have long-term impact on the global burden of disease. Pregnant women may be particularly vulnerable due to partial immune suppression. Besides physical vulnerability, they could be at increased risk of mental health problems, such as anxiety, depression, and post-traumatic stress disorder (PTSD), due to social distancing leading to less support from the family and friends, and in some cases, partners not being allowed to be present during prenatal visits, labor and delivery. Furthermore, many pregnant women may feel insecure and worried about the effect of COVID-19 on their unborn child, if they get infected during pregnancy. Today, young urban women are used to utilizing internet services frequently and efficiently. Therefore, providing mental health support to pregnant women via internet may be effective in ameliorating their anxiety/depression and reduce the risk of serious mental health disorders leading to improved maternal and perinatal outcomes.

NCT04363177 Perinatal Depression COVID19 Anxiety PTSD Pregnancy Related Behavioral: Web-based psychosocial peer-to-peer support

MeSH:Depression

4 Loneliness During the Non-pharmacological Epidemiological Interventions for the COVID-19 Pandemic in Norway: Risk Factors and Associations With Psychopathology

The present study of loneliness during the COVID-19-related NPIs is part of a larger project aiming to investigate psychological reactions and symptoms associated with the current and ongoing governmental initiatives in place in Norway. The results will lead to a better understanding of the psychological effects on quarantine on the population and consequently will be relevant for the development of tailored prevention and intervention programs fit for pandemic crises. Objectives Investigate the levels of loneliness in a general population during the strict social distancing government-initiated non-pharmacological interventions (NPIs) for the COVID-19 pandemic. Investigate risk and resilience factors for loneliness and the associations between loneliness and psychopathology symptoms during the NPIs. Aims Inform the general public, policy makers, scientists, and health practitioners about the associations of the NPIs with the mental health problem of loneliness and its potential effect on psychopathology. Provide a foundation for policymakers and health-care professionals to employ interventions that protect the general public against increased psychological suffering and dysfunction during society's handling of pandemics.

NCT04365881 Loneliness, Worry, Rumination, Health Anxiety, Depression, Anxiety Other: Cross-sectional observational study

MeSH:Depression

5 Getting it Right: Towards Responsible Social Media Use During a Pandemic (COVID-19)

In this protocol, we seek to examine the role of social media in information spread during a pandemic. As there have been few pandemics in the last decade (coinciding with the rise of social media), its use in this context remains understudied. This study hence intends to: (1) characterize the nature of social media use, (2) understand the impact of social media use, and (3) understand how to communicate accurate information.

NCT04367363 Coronavirus Depression Anxiety Stress Behavioral: Social media & news consumption

MeSH:Coronavirus Infections Depression

6 Impact of Giving Birth During the Covid 19 Pandemia on Postnatal Women's Depression

Postnatal depression is an important problematic in French population with approximatively 10 -20% of women who suffer from postnatal depression. This pathology may have strong negative impact on both women and neonate's health. The women's satisfaction degree in front of childbirth is an important factor associated with postnatal depression since women unsatisfied of their childbirth and/or women with a complicated childbirth are more encline to suffer from postnatal depression. It is likely that the actual context of Covid 19 pandemia and the change in obstetrical cares organization may have a negative impact on women's satisfaction about their childbirth and so a negative impact on the risk of postnatal depression.

NCT04368208 Postnatal Depression Other: Assessment of postnatal depression using the the Edinburgh questionnaire between 4 and 6 weeks after delivery

MeSH:Depression, Postpartum Depression Depressive Disorder

HPO:Depressivity

7 Prevalence Of Anxiety And Depression During COVID-19

1. To understand the prevalence of symptoms of Depression and Anxiety in general population during COVID-19 in India 2. To understand correlation between COVID-19 related factors and mental health symptomology in the general population in India Hypothesis: There is likelihood of significant symptoms of depression and anxiety among general population in India during the current COVID-19 outbreak. Procedure: The participants would be selected with their informed consent. The objective of the study would be clearly written on Page 1 of the survey. The test would be administered electronically by all the participants individually only when consented to the study. The data collected will be kept strictly confidential and the identity of the participants will not be disclosed at any point of the research Measures: 1. Demographic Information Demographic variables included Gender, Age, Place of Stay, Marital Status, Highest Level ofEducation, current living arrangement (e.g. staying alone or with family) and Occupation. It further includesregular employment status and current employment status(e.g, Work from home, temporary leave, termination etc) 2. History of illness (Present or past) History of physical ailment specified (diabetes, hypertension, heart ailment or being on any steroid or any other chronic ailment) Previous history of H1N1/ Influenza like illness 3. COVID-19 Information This section includes time spent focusing on COVID related information, current stressors with respect to COVID-19 and coping mechanisms used. This further includesinformation on resources available to participants near their place of stay and information of any known diagnosed case of COVID-19. 4. Standardized Scales to be used Generalized Anxiety Disorder Scale (GAD-7); Patient Health Questionnaire (PHQ-9) Powered by

NCT04369300 COVID-19 Behavioral: Registery Data Collection

MeSH:Depression

8 Level and Predictors of Trauma-symptoms Among Health Workers and Public Service Providers During the COVID-19 Outbreak

The aim of this study is to investigate the levels of trauma and mental symptoms (i.e., depression and anxiety) among health workers and public service providers during the strict social distancing government-initiated non-pharmacological interventions (NPI's) related to the COVID-19 pandemic. The study also aims to investigate predictors of trauma-symptoms.

NCT04374097 Post Traumatic Stress Disorder Anxiety Depression

MeSH:Depression Stress Disorders, Traumatic Stress Disorders, Post-Traumatic

9 Descriptive Study of the PSYchological Impact of CONFinement Measures in Subjects With Mood Disorders : PsyConf

Quarantine is an unpleasant experience : separation from loved ones, loss of freedom, uncertainty about infection status, boredom .It may lead to negative mental health consequences and thus the emergence of anxiety and depressive symptoms. Poor social contacts and history of psychiatric disorders are factors increasing the negative psychological impact of confinement. Patients with psychiatric disorders are therefore particularly vulnerable during quarantine. Only one study has reported that history of psychiatric disorder was associated with a higher risk of anxiety and anger at 4 - 6 months after the end of quarantine. Since March 17th, 2020 the French government has implemented national containment measures due to the Covid-19 epidemic. This situation has led to a reorganization of care as requested on March 22nd, 2020 in the recommendations applicable to the organization of care in psychiatric services: priority to telephone contacts and teleconsultations by multiplying contacts and assessments. As part of the telephone contacts that are now part of the recommended care, patients are systematically interviewed on the impact of the confinement situation on their psychological well-being with self-questionnaires used in the daily clinical practice. Assessing the negative psychological impact in patients with a psychiatric history is essential to better deploy post-confinement management. This assessment will provide preliminary indicators for the appropriate organization of care.

NCT04374643 Depression, Unipolar COVID 19 Other: Questionnaire to study the psychological impact of confinement

MeSH:Depression Depressive Disorder Mood Disorders

HPO:Depressivity

10 Risk Factors for Anxiety and Depression Among Pregnant Women During the COVID-19 Pandemic - a Web-based Cross-sectional Survey

The article presents a protocol of a cross-sectional study of mental health of pregnant women in relation to the COVID 19 pandemic. The primary aim is to compare differences in anxiety and depression scores of pregnant women between countries affected by the COVID-19 pandemic. The secondary aim is to assess demographic, economic, and social aspects affecting maternal anxiety and depression scores among pregnant women worldwide in the time of the COVID-19 pandemic. Finally, investigators will be able to compare differences in perception of the different aspects of the COVID-19 pandemic (social distancing, restrictions related to delivery) between countries and according to the epidemic status (number of infected patients, number of reported deaths). The comparisons will also be done according to COVID-19 status of the participants.

NCT04377412 Anxiety Depression Pregnancy Related Other: Pandemic control measures

MeSH:Depression Depressive Disorder Anxiety Disorders

HPO:Depressivity

11 Efficacy of Therapist Guided e-Therapy Versus Self-Help Therapy on Psychological Distress Among Individuals in Oman During COVID-19 Pandemic: An Open-Label 12 - Weeks Randomized Controlled Trail

Background: COVID-19 (Corona Virus Disease 2019) is a virulent infectious disease with an incubation period ranging between 2-14 days. This highly contagious disease is caused by Sars-Cov-2 (Severe Acute Respiratory Syndrome Coronavirus 2). The number of people infected by COVID-19 has increased exponentially since January as a result of traveling and contact with COVID-19 infected individual. Initially, the seriousness of COVID-19 was not gauged properly until World Health Organization classified it as Pandemic type infectious disease and rapidly made plans actions to fight against it on 20 January, 2020. The uncertainty and low predictability of COVID-19 not only threaten people's physical health, but also affect people's mental health, especially in terms of emotions and cognition. As consequence of public emergency, with its economic health and social impacts, psychological repercussions among people are inevitable at the short and long term. Importance and justify the study: This study will assess the effectiveness of e therapy in treating anxiety and depression during a pandemic. This would be a novel way of providing therapy during crises Hypothesis: We hypothesize that compared to self-help email delivered therapy, the therapist guided e-Therapy is more efficacious in reducing the level of psychosocial stress among distressed individuals in Oman during COVID19. Objective: The aim of this study is to assess the efficacy of six weeks therapist guided e-Therapy versus Self-help e-mail delivered therapy on Psychological distress among random sample of individuals live in Oman during COVID 19 pandemic. This study will recruit 60 participants from a list respondents to public survey who reported high levels of depression and anxiety, and randomize them to either therapist guided e-psychotherapy(intervention) or (control) self-help arms. Participants in the intervention arm will receive six sessions of therapist guided e therapy as described in the study schedule. Participants in the control arm will receive self-help psychotherapy contents similar to the intervention arm as detailed in the study schedule. Throughout the study, outcome and safety assessments will be conducted.

NCT04378257 Depressive Symptoms Generalized Anxiety Behavioral: Therapist Guided E-Therapy Behavioral: Self-Help Therapy

MeSH:Depression

12 ''(COVID-19) and Anxiety and Depressive Symptoms in Pregnant Women"

In our study; Anxiety and depression levels, socio-demographic characteristics of the pregnant women who were admitted to our hospital between 25.04.2020-25.07.2020 and treated with the diagnosis of covid 19, and the change in anxiety and depression levelsWİTH Beck Depression and Anxiety Score after the disease regressed are planned. (Beck depression scale contains 10 questions and a total of 1 to 100 points is obtained. High score indicates that depression and anxiety are high.) 0-16 points = mild depressive symptoms 17-29 points = moderate depressive symptoms 30-63 points = severe depressive symptoms

NCT04384887 COVID Anxiety Depression, Postpartum Behavioral: covid-19 positive pregnant women

MeSH:Depression, Postpartum Depression Anxiety Disorders

13 Impact of Covid-19 Pandemic on Depression and Quality of Life: Cross Sectional Study on Turkish Society and Suggestions on Potential Solution

It is aimed to investigate the depression and quality of life of Turkish society caused by Covid-19 pandemic and reveal the relationship between them

NCT04394078 Depression Quality of Life Covid 19 Social Isolation Other: Online survey

MeSH:Depression Depressive Disorder

HPO:Depressivity

14 Effects of Cognitive Behavariol Brief Therapy on Perceived Stress Level and Anxiety, Depression and Post Trauamatic Stress Symptoms in Medical Residents and Medical Staff During CoVID 19 Pandemics

The purpose of the study is to demonstrate the effect of brief behavarioul cognitive therapy through telepsychiatry.

NCT04394455 Anxiety Depressive Symptoms Post Traumatic Stress Symptoms Behavioral: Brief cognitive behavioural therapy Behavioral: Crisis intervention therapy

MeSH:Depression Anxiety Disorders

HPO Nodes