CovidResearchTrials by Shray Alag


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Questionnaire to study the psychological impact of confinementWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (0)


Name (Synonyms) Correlation

Correlated MeSH Terms (3)


Name (Synonyms) Correlation
D019964 Mood Disorders NIH 1.00
D003866 Depressive Disorder NIH 0.45
D003863 Depression, NIH 0.27

Correlated HPO Terms (1)


Name (Synonyms) Correlation
HP:0000716 Depressivity HPO 0.45

There is one clinical trial.

Clinical Trials


1 Descriptive Study of the PSYchological Impact of CONFinement Measures in Subjects With Mood Disorders : PsyConf

Quarantine is an unpleasant experience : separation from loved ones, loss of freedom, uncertainty about infection status, boredom .It may lead to negative mental health consequences and thus the emergence of anxiety and depressive symptoms. Poor social contacts and history of psychiatric disorders are factors increasing the negative psychological impact of confinement. Patients with psychiatric disorders are therefore particularly vulnerable during quarantine. Only one study has reported that history of psychiatric disorder was associated with a higher risk of anxiety and anger at 4 - 6 months after the end of quarantine. Since March 17th, 2020 the French government has implemented national containment measures due to the Covid-19 epidemic. This situation has led to a reorganization of care as requested on March 22nd, 2020 in the recommendations applicable to the organization of care in psychiatric services: priority to telephone contacts and teleconsultations by multiplying contacts and assessments. As part of the telephone contacts that are now part of the recommended care, patients are systematically interviewed on the impact of the confinement situation on their psychological well-being with self-questionnaires used in the daily clinical practice. Assessing the negative psychological impact in patients with a psychiatric history is essential to better deploy post-confinement management. This assessment will provide preliminary indicators for the appropriate organization of care.

NCT04374643 Depression, Unipolar COVID 19 Other: Questionnaire to study the psychological impact of confinement
MeSH:Depression Depressive Disorder Mood Disorders
HPO:Depressivity

Primary Outcomes

Description: depressive symptomatology with Patient Health Questionnaire

Measure: Depressive Symptomatology

Time: during confinement

Secondary Outcomes

Description: depressive symptomatology with Patient Health Questionnaire

Measure: Depressive Symptomatology

Time: post-confinement : 15 days, 3 months, 6 months

Other Outcomes

Description: Psychological pain : likert scale

Measure: Psychological pain

Time: confinement

Description: quality of sleep assessed with Insomnia Seveity Index

Measure: sleep

Time: confinement

Description: quality of sleep assessed with Insomnia Seveity Index

Measure: sleep

Time: post-confinement (15 days, 3 months, 6 months)

Description: anxiety intensity assessed by Generalized Anxieety Disorder

Measure: anxiety

Time: confinement

Description: anxiety intensity assessed by Generalized Anxieety Disorder

Measure: anxiety

Time: post-confinement (15 days, 3 months, 6 months)

Description: psychological pain : likert scale

Measure: psychological pain

Time: post-confinement (15 days, 3 months, 6 months)

Description: psychological pain : likert scale

Measure: physical pain

Time: confinement

Description: psychological pain : likert scale

Measure: physical pain

Time: post-confinement (15 days, 3 months, 6 months)

Description: staxi state scale

Measure: anger

Time: confinement

Description: staxi state scale

Measure: anger

Time: post-confinement (15 days, 3 months, 6 months)

Description: Assessed by the Stressful Event Impact Scale - Horowitz

Measure: Stressful Event Impact

Time: confinement

Description: Assessed by the Stressful Event Impact Scale - Horowitz

Measure: Stressful Event Impact

Time: post-confinement (15 days, 3 months, 6 months)

Description: declarative psychotropic drugs consumption

Measure: Use of psychotropic drugs

Time: confinement

Description: declarative psychotropic drugs consumption

Measure: Use of psychotropic drugs

Time: post-confinement (15 days, 3 months, 6 months)

Description: declarative consumption

Measure: Tobacco consumption

Time: confinement

Description: declarative consumption

Measure: Tobacco consumption

Time: post-confinement (15 days, 3 months, 6 months)

Description: declarative consumption

Measure: alcohol consumption

Time: post-confinement (15 days, 3 months, 6 months)

Description: declarative consumption

Measure: alcohol consumption

Time: confinement

Description: declarative consumption

Measure: Illicit substances consumption

Time: confinement

Description: declarative consumption

Measure: Illicit substances consumption

Time: post-confinement (15 days, 3 months, 6 months)

Description: LOT-R questionnaire

Measure: orientation of life

Time: confinement

Description: LOT-R questionnaire

Measure: orientation of life

Time: post-confinement (15 days, 3 months, 6 months)


Related HPO nodes (Using clinical trials)


HP:0000716: Depressivity
Genes 381
TRNF ARSG FUS ANG PDE11A GLE1 SARS1 PLA2G6 NEK1 SLC18A2 HLA-DRB1 FMN2 TRNS2 XK SMPD1 HTT CHD7 ATXN10 SNCAIP TCF4 ATP1A3 GPR101 DRD2 PDGFB OPTN TWNK RRM2B GBA KCNT1 BCR JPH3 NOTCH3 PDCD1 PAH PIGC HTR2A PRKN DNMT1 TRNL1 ZC3H14 ST3GAL3 USH1G LMNB1 LIMK1 SNCA ADH1C ATRX OCRL PRKACA TBL2 FMR1 PRNP CPOX USP8 PPARGC1A UCHL1 VPS13C GLUD2 KCNJ2 TBK1 MST1 TWNK MSTO1 MAPT B3GALNT2 PPP2R2B PROKR2 PRNP XPR1 RPS20 POLG SQSTM1 ARMC5 NDST1 TRNN TARDBP USH2A TRNL2 GNAS DCPS STX16 TTC19 ATXN10 SLC20A2 TBX1 CSF1R GSN ND1 ATP7B CDH23 TAC3 MYO7A WFS1 TWNK PDGFRB HS6ST1 PRKCG ESPN COX2 HIRA GNAS CLCN4 CASR ARSA GABRA1 GCH1 DNA2 MAPT UBQLN2 GDAP2 FGF8 TOR1A SEMA4A TK2 UFD1 FUS DGUOK EPM2A HARS1 C9ORF72 POLG UNC13A PODXL TBK1 LRRK2 CLIP2 HTRA2 DCTN1 TRAPPC9 C19ORF12 PLA2G6 MATR3 C12ORF4 GRIK2 SLC6A4 PRNP MECP2 CP HLA-DQB1 CFAP410 CACNA1G MED23 AARS2 VCP TRNQ PRNP JMJD1C SRPX2 VAPB MYO7A SGCE CC2D1A VPS35 ABCA7 CCNF EHMT1 C9ORF72 SNCA MLH1 PANK2 DUSP6 CEP78 GABRB3 FIG4 NR4A2 BMPR1A PTPN22 PARK7 MECP2 DNMT1 WASHC4 TRNS1 CACNA1G AMACR VCP ALMS1 IDUA CHMP2B PMS1 GIGYF2 KISS1R TSC1 RPS6KA3 COQ2 ERBB4 KDM5B POLG2 SEC24C SLC2A1 COQ2 DNAJC13 MSTO1 MSH6 FBXO31 RRM2B CHMP2B HTT POLG EDC3 PGAP1 NSMF SLC25A4 ATXN2 PIK3CA THOC2 PER2 GLA CACNA1H TBC1D7 PAH SQSTM1 POLG GNAS PRNP AIMP1 ARMC5 CIB2 LINS1 GABRG2 FGFR1 C9ORF72 CDH23 METTL23 TACR3 EPCAM TRNS1 PPOX KRAS ANOS1 SLC45A1 WARS2 POLG FA2H COASY HLA-DQB1 GNAS TRNL1 PRSS12 CLN6 GBA PMS2 C9ORF72 CLCN4 HBB TSC2 PDGFB AIP PRKAR1A COMT MAPT DNAJC5 CRADD ATXN8 ATXN2 ATP13A2 ARVCF GTF2I WHRN GBA TRNW COX3 KISS1 TREM2 TGFBR2 PDZD7 AFG3L2 PDGFRB BCS1L MAN1B1 SNCA VCP NEFH TRNH COX1 ATP1A3 DAO CPOX PINK1 LRRK2 HMBS CRBN DCTN1 CTSF GPR35 CLIP1 TBX1 ND5 TAF15 ND4 PTS PON3 MED25 DNAJC6 TRNS2 NSUN2 FMO3 SPAST HMBS FGF17 ELN PON1 CBS CYP27A1 FGF14 PSAP FMR1 TMEM106B KCTD17 RREB1 CHCHD10 TWNK TBP AP2S1 ATXN8OS FRRS1L ATXN8OS BAZ1B HNMT FAN1 ADGRV1 PINK1 HNRNPA1 PRPH TUSC3 MBOAT7 PRNP PANK2 FGF14 GABRG2 KCTD17 PDGFRB TECR LMAN2L EIF4G1 GNAS CLRN1 EPHA4 GP1BB JRK IQSEC1 TREM2 MSH2 PSEN1 RFC2 PON2 MAPK1 SGCE PER3 PROK2 GRIN2A TNIK PFN1 MLH3 GRN ND6 CRKL ANXA11 C9ORF72 GNRHR EZR VCP USH1C GNRH1 TOR1A WFS1 POLG NHLRC1 CISD2 CHCHD10 WDR11 SPRY4 PPT1 PCDH15 TBP GTF2IRD1 SOD1 RSRC1 GLT8D1 DCTN1 GNA11 TARDBP
Protein Mutations 4
A1298C C677T V158M V66M