There are 2 clinical trials
The current COVID-19 pandemic, this is especially since the transmission of SARS-CoV-2 is thought to occur mainly through respiratory droplets generated by coughing and sneezing, by direct contact with contaminated surfaces and because in a large number of patients COVID-19 disease may be asymptomatic. As recommended by the CDC medical personnel should be equipped with full personal protective equipment (PPE) for AGP in contact with suspected/confirmed COVID-19 patient. Therefore, it is reasonable to search for the most effective methods of intravascular access in those conditions.
Description: successful placement of intravascular device
Measure: Success rate of first intravascular access attempt Time: 1 dayDescription: time to successful access
Measure: time to successful access Time: 1 dayDescription: number of attempts to successful access
Measure: number of attempts to successful access Time: 1 dayDescription: time to therapy including but not limited to time to fluids, antibiotics, and antiarrythmics
Measure: time to infusion Time: 1 dayDescription: complication rates
Measure: complication rates Time: 1 dayDescription: the rate of survival to hospital admission
Measure: ROSC Time: 1 daySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the novel coronavirus disease 2019 (COVID-19) pandemic. Among COVID-19 complications, in-hospital cardiac arrest (IHCA) was reported with a very poor outcome in a retrospective single-center study (0,7% of 30 days survival with good neurological outcome among IHCA patients with a resuscitation attempt), related to its natural course and management. The incidence of unexpected in-ICU cardiac arrest (ICUCA) due to COVID-19 is still unknown. Additionally, outcome of COVID-19 patients admitted in ICU for an out-of-hospital cardiac arrest (OHCA) is also undescribed. The objective this study is : - to report the incidence of ICUCA among patients hospitalized in French ICU for COVID-19. - to report morbidity and mortality among COVID-19 patients admitted alive in ICU for an OHCA or an IHCA. The secondary objective is to assess outcome and identify risk factors of ICUCA occurrence among patients admitted for COVID-19.
Description: Percentage of unexpected in-intensive care unit cardiac arrest among COVID-19 patients admitted to intensive care unit
Measure: Incidence of unexpected cardiac arrest Time: 7 monthsDescription: Diabetes, hypertension, smoking, dyslipidemia, coronary artery disease, chronic respiratory insufficiency, chronic heart failure, chronic renal insufficiency, chronic hepatic insufficiency, chronic neurological disease, cancer, malignant hemopathy. Charlson score's minimum and maximum values are 0 and 40 respectively, the lowest score corresponds to a better outcome.
Measure: Charlson score Time: 7 monthsDescription: Respiratory failure, neurological impairment, circulatory failure, hepatic failure, haematological failure, renal failure. Sofa score's minimum and maximum values are 0 and 24, the lowest score corresponds to a better outcome
Measure: Organ failure score at ICU admission and/or before unexpected in-ICU cardiac arrest Time: 7 monthsDescription: Cardiac origin; Respiratory origin; Metabolic origin; unknown origin
Measure: Etiology retained to explain cardiac arrest occurrence Time: 7 monthsDescription: 0 - no symptoms at all - no significant disability despite symptoms; able to carry out all usual duties and activities - Slight disability; unable to carry out all previous activities, but able to look after own affairs without assistance - Moderate disability; requiring some help, but able to walk without assistance - Moderately severe disability; unable to walk and attend to bodily needs without assistance - Severe disability; bedridden, incontinent and requiring constant nursing care and attention - Dead
Measure: Modified Rankin score (mRS) at ICU discharge, at hospital discharge and at 3 months Time: 3 months