CovidResearchTrials by Shray Alag


CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)


Report for D060085: Coinfection NIH

(Synonyms: Coinfection)

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (3)


Name (Synonyms) Correlation
drug353 Defibrotide 25 mg/kg 24 hours continuous infusion for 15 days Wiki 1.00
drug853 Placebo 250 cc 24 hours continuous infusion for 15 days Wiki 1.00
drug439 FilmArray Pneumonia Wiki 1.00

Correlated MeSH Terms (0)


Name (Synonyms) Correlation

Correlated HPO Terms (0)


Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials


1 Co-infections in COVID-19 Critically Ill and Antibiotic Management

International guidelines suggest the administration of empirical broad-spectrum antibiotics for suspected bacterial co-infection in COVID-19 critically ill. However, data on associated respiratory infections is rare and antimicrobial stewardship interventions promoting antibiotic savings are non-existent in this context. The main objectives of the trial are: to evaluate the rate of co-infections among COVID-19 critically ill to evaluate the added value of a a rapid molecular diagnostic tool (FA-PNEU) to detect the presence of co-infecting pathogens in order to rapidly tailor the patient's antibiotic treatment

NCT04382092 COVID-19 Diagnostic Test: FilmArray Pneumonia
MeSH:Coinfection

Primary Outcomes

Description: COVID-19 infections with additional bacteria/viruses identified through FA-PNEU testing

Measure: % of COVID-19 co-infections

Time: through study completion, an average of 1 month

Secondary Outcomes

Description: The rapid FA results could allow a fast modification of the empirical antibiotherapy. This percentage will be measured.

Measure: % of antibiotic switches following FA results

Time: through study completion, an average of 1 month


HPO Nodes