Covid 19 Research using Clinical Trials (Home Page)
Report for D008457: Measles NIH
(Synonyms: Me, Measles)
Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation
Correlated Drug Terms (2)
| Name (Synonyms) | Correlation | |
|---|---|---|
| drug684 | Measles-Mumps-Rubella Vaccine Wiki | 1.00 |
| drug872 | Placebos Wiki | 0.25 |
Correlated MeSH Terms (0)
| Name (Synonyms) | Correlation |
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Correlated HPO Terms (0)
| Name (Synonyms) | Correlation |
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There is one clinical trial.
Clinical Trials
1 Effectiveness of Measles Vaccine in Health Care Professionals During COVID-19 Outbreak (Randomized Controlled Trial)
Till now, mortality reports among children below 9 years remains extremely low despite that the incidence of death toll is high and exceeding 50,000 patients among older population, One speculation for lower SARS infectivity is that cross-protective antibodies against measles vaccine ( MV). In mice susceptible to measles virus, recombinant MV induced the highest titers of neutralizing antibodies and fully protected immunized animals from intranasal infectious challenge with SARS-CoV, The primary objective of the present study is to determine the benefit of measles vaccine in health care professional to decrease the incidence of COVID-19. We Hypothesized that, measles vaccine may lower the incidence of serologically proven SARS-CoV-2 infection and reported respiratory illness
NCT04357028 Covid19 Drug: Measles-Mumps-Rubella Vaccine Drug: Placebos MeSH:Measles
Primary Outcomes
Description: Number of participants with asymptomatic or mild COVID-19 disease defined as fever (using self-reported questionnaire), plus at least one sign or symptom of respiratory disease including cough, runny/blocked nose (using self-reported questionnaire), plus positive SARS-Cov-2 test (PCR or serology)
Measure: COVID-19 disease incidence Time: Time Frame: Measured over the 6 months following randomizationSecondary Outcomes
Description: Number of pneumonia cases (abnormal chest X-ray) (using self-reported questionnaire and/or medical/hospital records) associated with a positive SARS-CoV-2 test
Measure: SARS-CoV-2 pneumonia Time: Time Frame: Measured over the 6 months following randomizationDescription: Number of days admitted to critical care (using self-reported questionnaire and/or medical/hospital records) associated with a positive SARS-CoV-2 test
Measure: Critical care admission duration with SARS-CoV-2 Time: Time Frame: Measured over the 6 months following randomizationDescription: Need for oxygen therapy (using self-reported questionnaire and/or medical/hospital records) associated with a positive SARS-CoV-2 test
Measure: Oxygen therapy with SARS-CoV-2 Time: Time Frame: Measured over the 6 months following randomization