Developed by Shray Alag, The Harker School
Sections: Correlations,
Clinical Trials, and HPO
Navigate: Clinical Trials and HPO
Navigate: Correlations HPO
There is one clinical trial.
This study is being performed to determine if a multi-ingredient dietary supplement is safe and easy to take by healthy older adults. Participants will be required to take one of three different doses of the dietary supplement for 90 consecutive days and complete wellness surveys and a daily log while taking the supplement. Participants will also provide blood samples at the start of the study, after 30 days, and at the end of the study which will help determine how participants respond to the supplement.
Description: Subjects are instructed to log any AEs that occur at any time during the study in the study journal. Participants will be contacted by phone after 7 days on the MTDS to assess any occurrence of AEs. Reported or observed AEs will be documented and followed to resolution.
Measure: Number of Participants With Treatment-Related Adverse Events (AE) as Assessed by CTCAE v5.0 Time: out to 90 daysDescription: Safety Assessment in Hematology
Measure: Hematocrit (%) Time: out to 90 daysDescription: Safety Assessment in Hematology
Measure: Hemoglobin (g/L) Time: out to 90 daysDescription: Safety Assessment in Hematology
Measure: Erythrocytes (10^12/L) Time: out to 90 daysDescription: Safety Assessment in Hematology
Measure: Leukocytes (10^9/L) Time: out to 90 daysDescription: Safety Assessment in Hematology
Measure: Basophils (10^3/uL) Time: out to 90 daysDescription: Safety Assessment in Hematology
Measure: Basophils/Leukocytes (%) Time: out to 90 daysDescription: Safety Assessment in Hematology
Measure: Eosinophils (10^9/L) Time: out to 90 daysDescription: Safety Assessment in Hematology
Measure: Eosinophils/Leukocytes (%) Time: out to 90 daysDescription: Safety Assessment in Hematology
Measure: Lymphocytes (10^9/L) Time: out to 90 daysDescription: Safety Assessment in Hematology
Measure: Lymphocytes/Leukocytes (%) Time: out to 90 daysDescription: Safety Assessment in Hematology
Measure: Monocytes (10^9/L) Time: out to 90 daysDescription: Safety Assessment in Hematology
Measure: Monocytes/Leukocytes (%) Time: out to 90 daysDescription: Safety Assessment in Hematology
Measure: Neutrophils (10^9/L) Time: out to 90 daysDescription: Safety Assessment in Hematology
Measure: Neutrophils/Leukocytes (%) Time: out to 90 daysDescription: Safety Assessment in Hematology
Measure: Platelet Count (10^9/L) Time: out to 90 daysDescription: Safety Assessment in Serum Chemistry
Measure: Serum Glucose (mmol/L) Time: out to 90 daysDescription: Safety Assessment in Serum Chemistry
Measure: Sodium (mmol/L) Time: out to 90 daysDescription: Safety Assessment in Serum Chemistry
Measure: Potassium (mmol/L) Time: out to 90 daysDescription: Safety Assessment in Serum Chemistry
Measure: Calcium (mmol/L) Time: out to 90 daysDescription: Safety Assessment in Serum Chemistry
Measure: Chloride (mmol/L) Time: out to 90 daysDescription: Safety Assessment in Serum Chemistry
Measure: Urea (mmol/L) Time: out to 90 daysDescription: Safety Assessment in Serum Chemistry
Measure: Creatinine (umol/L) Time: out to 90 daysDescription: Safety Assessment in Serum Chemistry
Measure: Urate (umol/L) Time: out to 90 daysDescription: Safety Assessment in Serum Chemistry
Measure: Albumin (g/L) Time: out to 90 daysDescription: Safety Assessment in Serum Chemistry
Measure: Alkaline Phosphatase (U/L) Time: out to 90 daysDescription: Safety Assessment in Serum Chemistry
Measure: Aspartate Phosphatase (U/L) Time: out to 90 daysDescription: Safety Assessment in Serum Chemistry
Measure: Alanine Transaminase (U/L) Time: out to 90 daysDescription: Safety Assessment in Serum Chemistry
Measure: Gamma Glutamyl Transpeptidase (U/L) Time: out to 90 daysDescription: Safety Assessment in Serum Chemistry
Measure: Total Bilirubin (umol/L) Time: out to 90 daysDescription: Safety Assessment in Serum Chemistry
Measure: Direct Bilirubin (umol/L) Time: out to 90 daysDescription: Safety Assessment in Serum Chemistry
Measure: Lactate Dehydrogenase (U/L) Time: out to 90 daysDescription: Safety Assessment in Serum Chemistry
Measure: High Sensitivity C-Reactive Protein (mg/L) Time: out to 90 daysDescription: Plasma Micronutrient Levels
Measure: Vitamin A (mg/L) Time: out to 90 daysDescription: Plasma Micronutrient Levels
Measure: Vitamin B1 (mg/L) Time: out to 90 daysDescription: Plasma Micronutrient Levels
Measure: Vitamin B2 (mg/L) Time: out to 90 daysDescription: Plasma Micronutrient Levels
Measure: Vitamin B3 (mg/L) Time: out to 90 daysDescription: Plasma Micronutrient Levels
Measure: Vitamin B6 (mg/L) Time: out to 90 daysDescription: Plasma Micronutrient Levels
Measure: Vitamin B12 (mg/L) Time: out to 90 daysDescription: Plasma Micronutrient Levels
Measure: Biotin (mg/L) Time: out to 90 daysDescription: Plasma Micronutrient Levels
Measure: Folate (mg/L) Time: out to 90 daysDescription: Plasma Micronutrient Levels
Measure: Pantothenate (mg/L) Time: out to 90 daysDescription: Plasma Micronutrient Levels
Measure: Vitamin C (mg/L) Time: out to 90 daysDescription: Plasma Micronutrient Levels
Measure: Vitamin D3 (mg/L) Time: out to 90 daysDescription: Plasma Micronutrient Levels
Measure: Vitamin K2 (mg/L) Time: out to 90 daysDescription: Plasma Micronutrient Levels
Measure: Magnesium (mg/L) Time: out to 90 daysDescription: Plasma Micronutrient Levels
Measure: Manganese (mg/L) Time: out to 90 daysDescription: Plasma Micronutrient Levels
Measure: Zinc (mg/L) Time: out to 90 daysDescription: Plasma Micronutrient Levels
Measure: Copper (mg/L) Time: out to 90 daysDescription: Plasma Micronutrient Levels
Measure: Alpha Lipoic Acid (mg/L) Time: out to 90 daysDescription: Plasma Micronutrient Levels
Measure: Glutamine (mg/L) Time: out to 90 daysDescription: Plasma Micronutrient Levels
Measure: Glutathione (mg/L) Time: out to 90 daysDescription: Plasma Micronutrient Levels
Measure: Carnitine (mg/L) Time: out to 90 daysDescription: Plasma Micronutrient Levels
Measure: Choline (mg/L) Time: out to 90 daysDescription: Plasma Micronutrient Levels
Measure: Inositol (mg/L) Time: out to 90 daysDescription: Plasma Micronutrient Levels
Measure: Coenzyme Q10 (mg/L) Time: out to 90 daysDescription: The SF-36 wellness questionnaire will be used to assess the health status of subjects. There are 36 individual questions which identify eight different facets of wellness. These have been described as physical functioning, role-physical, bodily pain, general health, vitality, social functioning, role-emotional, and mental health. These facets are further collapsed into physical and mental component summaries. The eight scaled scores, which are the weighted sums of the questions in their section. Each scale is directly transformed into a 0-100 scale on the assumption that each question carries equal weight. The lower the score the more disability. The higher the score the less disability i.e., a score of zero is equivalent to maximum disability and a score of 100 is equivalent to no disability. This questionnaire will be included in the study booklet given to each subject, and will be self administered.
Measure: 36-Item Short Form Survey (SF-36) Time: up to 90 daysAlphabetical listing of all HPO terms. Navigate: Correlations Clinical Trials
Data processed on December 13, 2020.
An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.
Drug Reports MeSH Reports HPO Reports