Developed by Shray Alag, The Harker School
Sections: Correlations,
Clinical Trials, and HPO
Navigate: Clinical Trials and HPO
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drug3086 | Parent Education Wiki | 0.71 |
drug554 | Baricitinib Wiki | 0.35 |
drug1293 | Dexamethasone Wiki | 0.29 |
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Navigate: Correlations HPO
There is one clinical trial.
The purpose of this study is to test the feasibility and efficacy of intervening with 2-year-old children with elevated temperamental Fear and/or Shyness or 3-year-old children with elevated anxiety and their parents, using a parent-child Cognitive Behavioral Therapy (CBT) protocol to reduce anxiety disorders and maintain reduced anxiety at one-year follow-up. Before the COVID-19 pandemic, study visits and treatment sessions were conducted in office. Now all visits and treatment sessions are conducted remotely.
Description: The CGI-I is a 7-point scale from 1 (Very Much Improved) to 7 (Very Much Worse). It will be rated by a clinician interviewer blind to treatment condition
Measure: Response Rate (proportion of participants rated as 1 or 2 on Clinical Global Impression of Anxiety-Improvement Measure (CGI-I) Time: Baseline to 1-Year Follow UpDescription: As measured by the Kiddie Schedule for Affective Disorders and Schizophrenia (KSADS-PL), a semi-structured interview used to assess present and lifetime severity of psychological disorders administered by a clinician blind to study arm
Measure: Mean Change in number of anxiety disorders Time: Baseline to 1-Year Follow UpDescription: The ECBQ Fear and Shyness scales include 23 items rated by a parent on a 7-point scale from 1 (Never) to 7 (Always)
Measure: Mean Change in Fear/Shyness Scores on the Early Childhood Behavior Questionnaire (ECBQ) (for those enrolled as 2-year-olds) Time: Baseline to Post-TreatmentDescription: The PAS consists of 28 items rated by a parent on a scale from 0 (Not True At All) to 4 (Very Often True). It assesses severity of anxiety in young children.
Measure: Mean Change in Anxiety Score on the Preschool Anxiety Scale (PAS) (for those enrolled as 3-year-olds) Time: Baseline to 1-Year Follow UpDescription: The CBCL and CRF are parent- and teacher/caregiver-completed questionnaires used to assess child behavior problems and social competence .
Measure: Mean change in Internalizing scores on the Child Behavior Checklist (CBCL) and Caregiver Report Form (CRF) where available for Ages 1-1/2 - 5 years Scores Time: Baseline to 1-Year Follow UpDescription: The FLIS contains 19 items on a scale from 0 (Not True) to 2 (Very True) rated by a parent and is used to assesses the extent to which child behavior limits participation in activities typical of families with young children
Measure: Mean change in family function on the Family Life Interference Scale (FLIS). Time: Baseline to 1-Year Follow UpDescription: This 42-item questionnaire, completed by the parent, assesses parental stress level
Measure: Mean change in Depression-Anxiety-Stress Scale stress rating Time: Baseline to 1-Year Follow-UpAlphabetical listing of all HPO terms. Navigate: Correlations Clinical Trials
Data processed on December 13, 2020.
An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.
Drug Reports MeSH Reports HPO Reports