There is one clinical trial.
This is an open-label, single-arm, multicenter phase II trial in patients with stage IV EGFR T790M, EGFR exon 20 and other uncommon, HER2, or BRAF-mutated; ALK, ROS1, or RET-rearranged NSCLC.
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Description: To define the by RECIST 1.1 of AUY922 in patients with stage IV EGFR T790M, EGFR exon 20 and other uncommon, HER2, or BRAF-mutated; ALK, ROS1, or RET-rearranged NSCLC
Measure: Objective response rate Time: Patients will be followed up for 2 years(post disease progression)Description: Patients will be followed for progression-free survival (PFS) and overall survival (OS) which will be analyzed by using a Kaplan-Meier curve. Patients will be followed up for PFS and OS for 2 years.
Measure: Efficacy, progression-free survival (PFS) Time: Patients will be followed up for PFS and OS for 2 years.(post disease progression)Description: Patients will be followed for overall survival (OS)
Measure: overall survival (OS) Time: Patients will be followed up for OS for 2 years.(post disease progression)