Developed by Shray Alag, The Harker School
Sections: Correlations,
Clinical Trials, and HPO
Navigate: Clinical Trials and HPO
Name (Synonyms) | Correlation | |
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drug2604 | Produce prescription program Wiki | 1.00 |
drug2942 | Saline containing 1% Human serum albumin(solution without UC-MSCs) Wiki | 1.00 |
drug3469 | UC-MSCs Wiki | 0.45 |
Name (Synonyms) | Correlation | |
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D014777 | Virus Diseases NIH | 0.11 |
D018352 | Coronavirus Infections NIH | 0.04 |
Name (Synonyms) | Correlation |
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Navigate: Correlations HPO
There is one clinical trial.
This study aims to compare the effectiveness of two interventions to address food insecurity among low-income families with young children during the COVID pandemic. The investigators will conduct a parallel group, randomized controlled trial of 250 families. The first randomly assigned comparator is Fresh Connect, a produce prescription program that provides a stipend for participants to purchase fresh food items at mobile markets and independent farmers markets across Boston. The second comparator is grocery store gift cards, redeemable at conventional grocery stores. In each comparator, participants will be given the equivalent of $150 on a monthly basis for six consecutive months. All participants will be followed for 12 months to assess outcomes that involve food insecurity (primary), fruit and vegetable consumption, healthcare utilization, social service utilization, and physical/emotional health.
Description: Self-reported food security status measured by USDA validated 18-question food insecurity screening tool with a 30-day lookback period. Responses are scored with total scores corresponding to four categories: high food security, marginal food security, low food security, and very low food security
Measure: Change in Food Security Time: Baseline, monthly for 12-months post-enrollmentDescription: Self-reported consumption frequency of fruits, fruit juices, and vegetables in the past 30 days measured by 10-item Dietary Screener Questionnaire scale. Each item is scored from "never" to "6 or more times per day". Scoring algorithms convert frequency responses to cup equivalent estimates of average daily dietary intake for fruits and vegetables, using an age and gender coefficient. The higher the score the more daily dietary intake for fruits and vegetables.
Measure: Change in fruit & vegetable consumption Time: Baseline, monthly for 12 months post-enrollmentDescription: Assessed by the Quick Inventory of Depressive Symptoms (QIDS SR-16). This scale is a 16-item self-report measure of depressive symptoms over the past 7 days. Each item is scored 0-3 (0 = no presence of the symptom; 3 = high burden of the symptom), yielding a total score range of 0 to 27. Because of its wide scoring range, the QIDS can be used to detect depressive illness in populations with low symptoms. Lower scores reflect less depressive symptoms.
Measure: Depression Symptoms Time: Baseline, monthly for 12-months post-enrollmentDescription: Assessed by the Beck Anxiety Inventory (BAI). This scale is a 21-item self-report measure the severity of self-reported anxiety. Each item is scored 0-3 (0 = not at all; 3 = severely - it bothered me a lot), yielding a total score range of 0 to 63. The lower the score the less self-reported anxiety.
Measure: Symptom Relief Time: Baseline, monthly for 12-months post-enrollmentDescription: Assessed by the Behavioral Activation for Depression Scale (BADS). This 25-item self-reported measure is used to track changes weekly in the behaviors hypothesized to underlie depression and specifically targeted for change by behavioral activation. The BADS subscales include activation, avoidance/rumination, work/school impairment, and social impairment. Each item is scored 0-6 (0=not at all; 6=completely), yielding a total score range of 0 to 150. High scores indicate greater levels of activation. For all the subscores, high scores are consistent with the subscale name.
Measure: Changes of behavioral activation for depression Time: Baseline, every 6 months during 12 month post-enrollmentDescription: Assessed by Perceived Stress Scale (PSS). This 14-item psychological instrument measures the perception of stress and the degree to which situations in one's life are appraised as stressful. Each item is scored 0-4 (0=never; 4= very often). The scores is obtained by first reversing the scores on items 4, 5, 6, 7, 9, 10, and 13 and then summing the reverse coded items with the rest of the items. The scores can range from 0 to 40 with higher scores indicating higher perceived stress.
Measure: Perceived Stress Time: Baseline, every 6 months during 12 month post-enrollmentDescription: Assessed by Social Adjustment Scale Self-Report (SAS-SR). This 54-item measure examines social and role functioning in six areas: work; social activities; relationships with family; spouse or partner; parent; member of family unit. Items are rated on a 5-point scale. Seven mean scores are generated, six-role areas and one overall means. The mean scores are converted into standard T-scores on the SAS-SR Profile Form. Higher scores indicate greater impairment of functioning.
Measure: Social Support Time: Baseline, every 6 months during 12 month post-enrollmentDescription: Assessed by Medical Outcomes Survey Social Support (MOSSS). This 18-item tool comprises 4 functional support scales (emotional/informational, tangible, affectionate, and positive interaction) and an overall social support index. Each item is scored 0-5 (0=none of the time; 5=all of the time). The higher the overall social support index the more support.
Measure: Medical outcomes social support Time: Baseline, every 6 months during 12 month post-enrollmentDescription: Assessed by Pearlin Mastery Scale (PMS). This 7-item tool measures the extent to which an individual regards their life chances as being under their personal control rather than fatalistically ruled. Each item is scored 1-4 (1=strongly agree; 4=strongly disagree) and the values are added. The scores can range from 7 to 28 with higher scores reflect greater mastery.
Measure: Mastery Control Time: Baseline, every 6 months during 12 month post-enrollmentDescription: Assessed by Rosenberg's Self-Esteem Scale (RSES). This 10-item self-report likert scale evaluates an individual's self-esteem. Each item is scored from strong agree to strongly disagree. The higher the sum of the scores, the higher the self-esteem.
Measure: Self-Esteem Time: Baseline, every 6 months during 12 month post-enrollmentDescription: Assessed by WE CARE. This 12-question screening tool assesses needs in 6 domains: parental educational attainment, employment, child care, risk of homelessness, food security, and household heat and electricity. Individuals respond with "Yes", "No", or "Maybe later". Those with unmet needs are provided with a locally developed community resource information sheet.
Measure: Unmet needs Time: Baseline, every 3 months during 12 month post-enrollmentDescription: Self-reported participation in food assistance programs including Electronic Benefits Transfer (EBT), Food Stamps/Supplemental Nutrition Assistance Program (SNAP).
Measure: Self-Reported Food Assistance Program Participation Time: Baseline, every 6 months during 12 month post-enrollmentDescription: Self-reported health status measured by a report of health status as excellent, very good, good, fair, or poor and measured by 3-item CDC Healthy Days module for a disarticulation of physical and mental health.
Measure: Change in Self-Reported Health Status Time: Baseline, monthly for 12-months post-enrollmentDescription: Assessed by the Pregnancy Risk Assessment Monitoring System (PRAMS). The survey Identifies groups of women and infants at high risk for health problems, monitors changes in health status, and measures progress towards goals in improving the health of mothers and infants.
Measure: Maternal attitudes and safe infant care practices Time: Baseline, every 6 months during 12 month post-enrollmentDescription: The Epidemic - Pandemic Impacts Inventory (EPII) + 4-item self-report of the impact of the pandemic on financial capacity and food purchasing/acquisition patterns. The EPII is newly developed, thus, scoring procedures will be determined by future research.
Measure: Impact of COVID-19 Time: Baseline, every 3 months during 12 month post-enrollmentDescription: Assessed by 4-item USDA program experience questions. The questions ask about firm type use, dose of program usage, health education, and program satisfaction.
Measure: Program Experience Time: 6 months post-enrollment, 12 months post-enrollmentDescription: Claims data composite measure (all cause hospital admissions and ED visits; Total number of all-cause ED visits; Total number of all-cause discharges from IP).
Measure: Change in adult acute healthcare utilization Time: Baseline, every 6 months during 12 month post-enrollmentDescription: Measured via claims data
Measure: Total adult patient-level cost of care Time: Baseline, every 6 months during 12 month post-enrollmentDescription: EPIC chart abstractions (number of office visits, hospitalizations, missed appointments, immunization rates)
Measure: Child healthcare utilization Time: Baseline, every 6 months during 12 month post-enrollmentDescription: EPIC chart abstractions (weight for age)
Measure: Child weight Time: Baseline, every 6 months during 12 month post-enrollmentDescription: EPIC chart abstractions (height for age)
Measure: Child height Time: Baseline, every 6 months during 12 month post-enrollmentAlphabetical listing of all HPO terms. Navigate: Correlations Clinical Trials
Data processed on December 13, 2020.
An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.
Drug Reports MeSH Reports HPO Reports