Developed by Shray Alag, The Harker School
Sections: Correlations,
Clinical Trials, and HPO
Navigate: Clinical Trials and HPO
Name (Synonyms) | Correlation | |
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drug335 | Azithromycin / Ivermectin / Ribaroxaban / Paracetamol Wiki | 1.00 |
drug336 | Azithromycin / Ribaroxaban / Paracetamol Wiki | 1.00 |
drug2448 | Placebo Wiki | 0.05 |
Name (Synonyms) | Correlation | |
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D013577 | Syndrome NIH | 0.10 |
D012127 | Respiratory Distress Syndrome, Newborn NIH | 0.08 |
D055371 | Acute Lung Injury NIH | 0.08 |
Name (Synonyms) | Correlation |
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Navigate: Correlations HPO
There is one clinical trial.
A randomized, double blind, multicenter, placebo-controlled, parallel group, fixed dose, phase II study to evaluate the efficacy and safety of glenzocimab in ARDS.
Description: Progression from moderate to severe assessed at Day 4 is a composite failure endpoint defined as the occurrence of at least one of the following failure events : Respiratory rate (RR) ≥ 30/min, or Oxygen Saturation (SpO2) ≤ 93% in resting state, or Oxygen Pressure/ Inspired fraction (PaO2/FiO2) ≤ 200mmHg Death occurring prior to or on Day 4
Measure: Progression from moderate to severe respiratory distress assessed at Day 4 Time: Day 4Description: WHO COVID-19 Ordinal Scoring Scale is 9 point ordinal scale
Measure: WHO-COVID-19 Scale Time: Up to Day 40Description: Determines the degree of illness of a patient and prompts critical care intervention (recommended by NHS over original NEWS): total possible score ranges from 0 to 20. The higher the scores the greater the clinical risk.
Measure: NEWS-2 Scale Time: Up to Day 40Description: Respiratory Rate status defined as:: o Normal:<20/min, Mild:20/min≤RR<24/min, Moderate:24/min≤RR<30/min, o Severe:≥30/min, Death.
Measure: Respiratory Rate status (RR) Time: Up to Day 40Description: Hypoxemia status defined as:: o Normal:>300mmHg,
Mild: 200 mmHg < PaO2/FiO2 ≤ 300 mmHg,
Moderate:100mmHg
Description: SpO2 status defined as: o Normal:>95%
Mild:93%
Description: Changes in one or several of the usual ECG parameters compared to baseline or screening, i.e. sinusal rhythm, cardiac axis, QRS value, QT/QTc segment, Wave direction, and any abnormality.
Measure: ECG over the course of the study versus screening Time: Up to Day 40Alphabetical listing of all HPO terms. Navigate: Correlations Clinical Trials
Data processed on December 13, 2020.
An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.
Drug Reports MeSH Reports HPO Reports