Developed by Shray Alag, The Harker School
Sections: Correlations,
Clinical Trials, and HPO
Navigate: Clinical Trials and HPO
Name (Synonyms) | Correlation |
---|
Name (Synonyms) | Correlation | |
---|---|---|
D008107 | Liver Diseases NIH | 0.25 |
D008171 | Lung Diseases, NIH | 0.15 |
Name (Synonyms) | Correlation |
---|
Navigate: Correlations HPO
There are 2 clinical trials
The purpose of this study is to compare 12-weeks of virtual multidisciplinary programming provided at three levels of support intensity to determine impacts on clinical outcomes, acceptability, and cost amongst outpatients with cancer, liver disease, or lung disease. Participants will be randomized to one of three groups: (i) standard care, (ii) a personnel-light app-based intervention, (iii) a personnel-intensive app-based intervention. Participants randomized to standard care will receive exercise and nutrition resources as well as a Garmin watch. Participants in the experimental groups will receive standard care, plus a 12-week multidisciplinary app-based personalized program involving 12 weeks of exercise programming and 10-weeks of nutrition programming. Participants in study group 3 will receive additional one-on-one care. The Research Ethics Board at the University of Alberta has approved this study. The protocol will measure patient-related outcome measures including physical function, quality of life, social isolation, and anxiety, as well as measures of acceptability and cost. 216 participants will take part in this study (n=72 per arm). Analyses: fitness testing and patient-reported outcomes will be administered before and after the intervention. Fitness and patient-reported outcomes will be compared using linear mixed models with random effects. App acceptability will be compared between groups using Chi-Square.
Description: The difference in the pre- vs post-intervention change in LEFS score between groups (score range: 0-80, higher scores indicate higher function)
Measure: Lower Extremity Functional Scale (LEFS) Time: 12 WeeksDescription: The difference in the pre- vs post-intervention change in UEFI score between groups (score range: 0-80, higher scores indicate higher function)
Measure: Upper Extremity Functional Index (UEFI) Time: 12 weeksDescription: The difference in the pre- vs post-intervention change in 6MWT distance between groups. Not possible if testing is virtual.
Measure: 6-Minute Walk Test (6MWT) Distance Time: 12 WeeksDescription: The difference in the pre- vs post-intervention change in # of repetitions completed over the Timed Sit-to-Stand between groups
Measure: Timed Sit-to-Stand (60 & 30 seconds) Time: 12 WeeksDescription: The difference in the pre- vs post-intervention change in Timed One-Legged Stance between groups
Measure: Timed One-Legged Stance Time: 12 WeeksDescription: The difference in the pre- vs post-intervention change in the # of steps completed in the 2MST between groups
Measure: 2-Minute Step Test (2MST) Time: 12 WeeksDescription: The difference in the pre- vs post-intervention change in the sit-and-reach distance between groups
Measure: Sit-and-Reach Time: 12 WeeksDescription: The difference in the pre- vs post-intervention change in step count and activity minutes (Garmin watch) between groups
Measure: Step Count & Activity Minutes Time: 12 WeeksDescription: The difference in the pre- vs post-intervention change in The World Health Organization-5 (WHO-5) Well-Being Index between groups (score range: 0-25, higher scores indicate higher well-being)
Measure: Overall Well-Being (The World Health Organization-5 [WHO-5] Well-Being Index) Time: 12 WeeksDescription: The difference in the pre- vs post-intervention change in resilience, as measures by the 10-Item Connor Davidson Resilience Scale, between groups (score range: 0-40, higher scores indicate higher resilience)
Measure: Resilience (10-Item Connor Davidson Resilience Scale) Time: 12 WeeksDescription: The difference in the pre- vs post-intervention change in health-related quality of life, as measured by the SF-36, between groups (score range: 0-100, higher scores indicate a more favorable health state)
Measure: General health-related quality of life (36-Item Short Form Survey [SF-36]) Time: 12 WeeksDescription: The difference in the pre- vs post-intervention change in health-related quality of life, as measured by the EQ-5D-5L, between groups (visual analogue score range: 0-100, higher scores indicate a more favorable health state)
Measure: General health-related quality of life (5-Level EQ-5D [EQ-5D-5L]) Time: 12 WeeksDescription: The difference in the pre- vs post-intervention change in proportion of "yes" answers to the single-item physical activity questionnaire from pre- to post-intervention between groups
Measure: Physical activity Time: 12 WeeksDescription: The difference in the pre- vs post-intervention change in sedentary time, as self-reported on the ISAT between groups
Measure: Sedentary Time (International Sedentary Assessment Tool - ISAT) Time: 12 WeeksDescription: The difference in the pre- vs post-intervention change in protein intake (grams) between groups, based on 3-day food record(s)
Measure: Protein Intake Time: 12 WeeksDescription: The difference in the pre- vs post-intervention change in calorie intake (kilocalories) between groups, based on 3-day food record(s)
Measure: Calorie Intake Time: 12 WeeksDescription: The difference in the pre- vs post-intervention change in micronutrient intake (milligrams) between groups, based on 3-day food record(s)
Measure: Micronutrient Intake Time: 12 WeeksDescription: The difference in the pre- vs post-intervention change in the 6-item COM-B scale between groups (score range: 0-120, higher scores indicate higher capability, opportunity, motivation)
Measure: Beliefs and outcome expectations about exercise Time: 12 WeeksDescription: The difference in the pre- vs post-intervention change in the UTAUT scale between groups (score range: 0-92, higher scores indicate higher app acceptance and use)
Measure: Program acceptability (Unified Theory of Acceptance and Use of Technology - UTAUT) Time: 12 WeeksThe purpose of this study is to compare 12-weeks of virtual multidisciplinary programming provided at three levels of support intensity to determine impacts on clinical outcomes, acceptability, and cost amongst outpatients with cancer, liver disease, or lung disease. Participants will be randomized to one of three groups: (i) standard care, (ii) a personnel-light app-based intervention, (iii) a personnel-intensive app-based intervention. Participants randomized to standard care will receive exercise and nutrition resources as well as a Garmin watch. Participants in the experimental groups will receive standard care, plus a 12-week multidisciplinary app-based personalized program involving 12 weeks of exercise programming and 10-weeks of nutrition programming. Participants in study group 3 will receive additional one-on-one care. The Research Ethics Board at the University of Alberta has approved this study. The protocol will measure patient-related outcome measures including physical function, quality of life, social isolation, and anxiety, as well as measures of acceptability and cost. 216 participants will take part in this study (n=72 per arm). Analyses: fitness testing and patient-reported outcomes will be administered before and after the intervention. Fitness and patient-reported outcomes will be compared using linear mixed models with random effects. App acceptability will be compared between groups using Chi-Square.
Description: The difference in the pre- vs post-intervention change in LEFS score between groups (score range: 0-80, higher scores indicate higher function)
Measure: Lower Extremity Functional Scale (LEFS) Time: 12 WeeksDescription: The difference in the pre- vs post-intervention change in UEFI score between groups (score range: 0-80, higher scores indicate higher function)
Measure: Upper Extremity Functional Index (UEFI) Time: 12 weeksDescription: The difference in the pre- vs post-intervention change in 6MWT distance between groups. Not possible if testing is virtual.
Measure: 6-Minute Walk Test (6MWT) Distance Time: 12 WeeksDescription: The difference in the pre- vs post-intervention change in # of repetitions completed over the Timed Sit-to-Stand between groups
Measure: Timed Sit-to-Stand (60 & 30 seconds) Time: 12 WeeksDescription: The difference in the pre- vs post-intervention change in Timed One-Legged Stance between groups
Measure: Timed One-Legged Stance Time: 12 WeeksDescription: The difference in the pre- vs post-intervention change in the # of steps completed in the 2MST between groups
Measure: 2-Minute Step Test (2MST) Time: 12 WeeksDescription: The difference in the pre- vs post-intervention change in the sit-and-reach distance between groups
Measure: Sit-and-Reach Time: 12 WeeksDescription: The difference in the pre- vs post-intervention change in step count and activity minutes (Garmin watch) between groups
Measure: Step Count & Activity Minutes Time: 12 WeeksDescription: The difference in the pre- vs post-intervention change in The World Health Organization-5 (WHO-5) Well-Being Index between groups (score range: 0-25, higher scores indicate higher well-being)
Measure: Overall Well-Being (The World Health Organization-5 [WHO-5] Well-Being Index) Time: 12 WeeksDescription: The difference in the pre- vs post-intervention change in resilience, as measures by the 10-Item Connor Davidson Resilience Scale, between groups (score range: 0-40, higher scores indicate higher resilience)
Measure: Resilience (10-Item Connor Davidson Resilience Scale) Time: 12 WeeksDescription: The difference in the pre- vs post-intervention change in health-related quality of life, as measured by the SF-36, between groups (score range: 0-100, higher scores indicate a more favorable health state)
Measure: General health-related quality of life (36-Item Short Form Survey [SF-36]) Time: 12 WeeksDescription: The difference in the pre- vs post-intervention change in health-related quality of life, as measured by the EQ-5D-5L, between groups (visual analogue score range: 0-100, higher scores indicate a more favorable health state)
Measure: General health-related quality of life (5-Level EQ-5D [EQ-5D-5L]) Time: 12 WeeksDescription: The difference in the pre- vs post-intervention change in proportion of "yes" answers to the single-item physical activity questionnaire from pre- to post-intervention between groups
Measure: Physical activity Time: 12 WeeksDescription: The difference in the pre- vs post-intervention change in sedentary time, as self-reported on the ISAT between groups
Measure: Sedentary Time (International Sedentary Assessment Tool - ISAT) Time: 12 WeeksDescription: The difference in the pre- vs post-intervention change in protein intake (grams) between groups, based on 3-day food record(s)
Measure: Protein Intake Time: 12 WeeksDescription: The difference in the pre- vs post-intervention change in calorie intake (kilocalories) between groups, based on 3-day food record(s)
Measure: Calorie Intake Time: 12 WeeksDescription: The difference in the pre- vs post-intervention change in micronutrient intake (milligrams) between groups, based on 3-day food record(s)
Measure: Micronutrient Intake Time: 12 WeeksDescription: The difference in the pre- vs post-intervention change in the 6-item COM-B scale between groups (score range: 0-120, higher scores indicate higher capability, opportunity, motivation)
Measure: Beliefs and outcome expectations about exercise Time: 12 WeeksDescription: The difference in the pre- vs post-intervention change in the UTAUT scale between groups (score range: 0-92, higher scores indicate higher app acceptance and use)
Measure: Program acceptability (Unified Theory of Acceptance and Use of Technology - UTAUT) Time: 12 WeeksAlphabetical listing of all HPO terms. Navigate: Correlations Clinical Trials
Data processed on December 13, 2020.
An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.
Drug Reports MeSH Reports HPO Reports