SNPMiner Trials by Shray Alag


SNPMiner SNPMiner Trials (Home Page)


Report for SNP rs316019

Developed by Shray Alag, 2020.
SNP Clinical Trial Gene

There is one clinical trial.

Clinical Trials


1 A Pharmacokinetic Evaluation of Metformin in Relation to the Polymorphism A270S in Healthy Caucasian Volunteers.

The aim of the study is to evaluate the pharmacokinetics of metformin in healthy Caucasians volunteers with and without the polymorphism A270S in OCT2,thus the study hypothesis is that renal clearance of metformin is affected in Caucasian with the known single nucleotide polymorphisms A270S in OCT2.

NCT01237522 Metformin Organic Cation Transporter 2 Polymorphism,Single Nucleotide Drug: Metformin

Inclusion Criteria: - Healthy volunteers - Written consent - rs316019 genotyped - Age 18-65 years old Exclusion Criteria: - Daily medication - Alcohol abuse - Pregnancy - Breastfeeding Inclusion Criteria: - Healthy volunteers - Written consent - rs316019 genotyped - Age 18-65 years old Exclusion Criteria: - Daily medication - Alcohol abuse - Pregnancy - Breastfeeding Metformin Organic Cation Transporter 2 Polymorphism,Single Nucleotide null

Primary Outcomes

Measure: Renal clearance of metformin

Time: 24 Hours


HPO Nodes