Developed by Shray Alag, The Harker School
Sections: Correlations,
Clinical Trials, and HPO
Navigate: Clinical Trials and HPO
| Name (Synonyms) | Correlation | |
|---|---|---|
| drug490 | BCG-Denmark Wiki | 0.41 |
| drug4801 | [14C]-radiolabelled BI 1358894 Wiki | 0.35 |
| drug3204 | Placebo (for Zonisamide) Wiki | 0.35 |
| Name (Synonyms) | Correlation | |
|---|---|---|
| drug496 | BI 1358894 Wiki | 0.35 |
| drug488 | BCG vaccine (Freeze-dried) Wiki | 0.35 |
| drug3194 | Pitolisant Wiki | 0.35 |
| drug1614 | FITSTART+ PBI Wiki | 0.35 |
| drug738 | CBD Isolate Wiki | 0.35 |
| drug1719 | Full Spectrum CBD Oil Wiki | 0.35 |
| drug2270 | Ketamine Hydrochloride Wiki | 0.35 |
| drug492 | BGB DXP593 Wiki | 0.35 |
| drug1776 | General Parenting Advice Wiki | 0.35 |
| drug4284 | Take Control Wiki | 0.35 |
| drug4754 | Woebot Substance Use Disorder Wiki | 0.35 |
| drug2746 | Naltrexone 380 MG Wiki | 0.35 |
| drug1509 | Enhanced linkage Wiki | 0.35 |
| drug1847 | HaRTC Wiki | 0.35 |
| drug3230 | Placebo Oil Wiki | 0.35 |
| drug493 | BGB-DXP593 Wiki | 0.35 |
| drug4796 | Zonisamide Wiki | 0.35 |
| drug3844 | Saline Wiki | 0.21 |
| drug486 | BCG Vaccine Wiki | 0.18 |
| drug487 | BCG vaccine Wiki | 0.18 |
| drug3195 | Placebo Wiki | 0.06 |
| Name (Synonyms) | Correlation | |
|---|---|---|
| D000428 | Alcohol Drinking NIH | 0.50 |
| D019966 | Substance-Related Disorders NIH | 0.27 |
| D015775 | Fractures, Stress NIH | 0.25 |
| Name (Synonyms) | Correlation |
|---|
Navigate: Correlations HPO
There are 8 clinical trials
Alcoholism is the third leading cause of preventable death in the US, accounting for 80,000 deaths annually. Almost 18 million US adults have alcohol use disorder (AUD); however, approved medications for the treatment of AUD has shown limited effectiveness. Zonisamide (ZON), a broad spectrum anticonvulsant, has proven to be more effective than a placebo in reducing alcohol intake in individuals with alcohol dependence. ZON's mechanism of action seems to be quite distinct from currently approved anti-alcoholism medications, which holds promise for treatment of individuals who are not responsive to conventional medications. However, much remains unknown about ZON's therapeutic mechanisms and ZON's efficacy in treating patients with a diagnosis of AUD. To fill in these gaps, the investigators will conduct a double-blind randomized controlled study that assesses ZON's treatment mechanisms and effectiveness in reducing alcohol consumption in patients with AUD. Participants will be randomized to one of two conditions: 1) treatment with ZON and a computerized psychotherapy platform called Take Control (TC); 2) treatment with a placebo (PLC) and TC. To understand the neurobiology behind ZON's potential therapeutic effects on AUD, fMRI will be used to compare the brain activity of the ZON+TC versus PLC+TC group while participants perform an alcohol and emotional-word Stroop task, as well as an alcohol related cues task.
Description: Drinking measures derived from Time Line Follow Back data will include the percent days drinking, the number of drinks consumed per day, and the percent days heavy drinking. Heavy drinking will be defined as 4 or more drinks per day for women and 5 or more drinks per day for men.
Measure: Alcohol Consumption Time: Change from baseline following 12-week treatmentDescription: The Risk Task (Rogers et al., 1999) measures decision-making under risk.
Measure: Risk Task - Risk Taking Behavior Time: Change from baseline at conclusion of 12-week treatmentDescription: The cued go no-go task (Fillmore, 2003) measures impulse control by the ability to inhibit instigated, "prepotent" responses.
Measure: Cued Go/No-go Task - Impulsivity Time: Change from baseline at conclusion of 12-week treatmentDescription: The Balloon Analogue Risk Task (BART) is a computerized measure of risk taking behavior. The BART models real-world risk behavior through the conceptual frame of balancing the potential for reward versus loss.
Measure: Balloon Analogue Risk Task - Risk Taking Behavior Time: Change from baseline at conclusion of 12-week treatmentDescription: The Continuous Performance Task (CPT) measures brain damage
Measure: Connors Continuous Performance Task - Impulsivity Time: Change from baseline at conclusion of 12-week treatmentThis randomized clinical trial will compare participants who receive HaRTC versus the nontreatment control arm to see if HaRTC helps urban American Indians and Alaska Natives who meet criteria for an alcohol use disorder to increase their engagement in cultural practices, enhance their quality of life, and reduce their alcohol-related harm.
Description: Alcohol and Substance Use Frequency Assessment items were adapted from the Addiction Severity Index-Fifth Edition (ASI-5th Ed) and will be used to assess frequency of alcohol use in the past 30 days. Scores range from 0 to 30 with higher scores indicating more frequent drinking.
Measure: Change in Alcohol frequency Time: Pre-intervention, mid-, immediate post-intervention, 1 month post-intervention, 3 months post intervention, and 6 months post-intervention.Description: The Alcohol Quantity and Use Assessment was created by the research team for previous studies with a similar population and will be used to record the quantity of alcohol consumed on participants' heaviest, typical, and lightest drinking days in the past month. Scores are expressed in number of standard drinks with higher numbers indicating heavier drinking.
Measure: Change in Peak alcohol use Time: Pre-intervention, mid-, immediate post-intervention, 1 month post-intervention, 3 months post intervention, and 6 months post-intervention.Description: The Short Inventory of Problems-2nd Revision (SIP-2R), a psychometrically reliable and valid 15-item, Likert-scale questionnaire, measures social, occupational, and psychological problems related to alcohol use. Scores range from 0 to 45 with higher scores indicating more severe alcohol-related harm.
Measure: Change in Alcohol-related harm Time: Pre-intervention, mid-, immediate post-intervention, 1 month post-intervention, 3 months post intervention, and 6 months post-intervention.Description: The EuroQoL-5 Dimensional-5 Level is a widely used generic measure of health status consisting of two parts. The first part (the descriptive system) assesses health in five dimensions (MOBILITY, SELF-CARE, USUAL ACTIVITIES, PAIN / DISCOMFORT, ANXIETY / DEPRESSION), each of which has five levels of response (no problems, slight problems, moderate problems, severe problems, extreme problems/unable to). Each domain is rated on a 5 point likert scale. Scores range from 5-25, with higher scores indicating poorer health related quality of life.
Measure: Change in EuroQoL-5 Dimensional-5 Level Time: Pre-intervention, mid-, immediately post-intervention, 1 month post-intervention, 3 months post intervention, and 6 months post-intervention.Description: **Self-report data for cost-effectiveness analyses -The Non-Study Resources Form: documents change in medical and nonmedical resources used by participants.
Measure: Change in Cost effectiveness Time: 6 months before study participation compared to 6 months after enrollment.Description: Ethyl glucuronide (EtG) urine tests will be used to validate self-reported alcohol use at each assessment. EtG, a metabolite of ethyl alcohol formed in the body after ethanol exposure, reflects alcohol consumption over the previous 72 hours. EtG (cutoff 300 mg/nl) will serve as a secondary outcome in analyses.
Measure: Change in Ethyl glucuronide Time: Pre-intervention, mid-, immediately post-intervention, 1 month post-intervention, 3 months post intervention, and 6 months post-intervention.Description: The Cultural Connectedness Scale is a 29-item Likert type measure consisting of 3 dimensions: identity, traditions, and spirituality. Scores can range from 29-145, with higher scores indicating a greater degree of cultural connectedness. Criterion validity was demonstrated with cultural connectedness dimensions adequately correlating with other indicators of wellness. The resulting scale scores will represent the proposed mediator in this study.
Measure: Change in Cultural connectedness Time: Pre-intervention, mid-, immediately post-intervention, 1 month post-intervention, 3 months post intervention, and 6 months post-intervention.This study seeks to gather data and insight on epidemiologic trends of loneliness and other behaviors in the wake of the CDC recommended "social distancing" during the COVID-19 pandemic. The objective of this study is to use a cross-sectional survey to assess the impact of COVID-19's associated recommendations (social distancing, self-isolation, and self-quarantine) on loneliness and psychosocial symptomatology (depression, anxiety, substance abuse) on young adults (18-35 years old).
Description: University of California Los Angeles ( UCLA) Loneliness Scale is a 20-item self-report questionnaire that evaluates subjective feelings of loneliness and social isolation. Participants rate items on a 4-point Likert scale ranging from 1 (never) to 4 (often).Items are summed to create a score that can range from 20-80, higher scores being indicative of greater loneliness.
Measure: Loneliness as evaluated by the UCLA loneliness scale Time: Day 1Description: Alcohol Use Disorder Identification Test (AUDIT) is a 10-item self-reported questionnaire used to identify individuals whose alcohol consumption could be hazardous for their health. Participants rate items in a 5-point Likert scale, indicating amount (0 to 10 drinks or more), frequency (never to daily or almost daily), and indication of problems caused by alcohol (yes or no). Items were summed up to create a score that can range from 0 to 50. A score of 1 to 7 indicates low risk consumption, whereas a score of 8-15 suggests risky or hazardous drinking, a score of more than 15 is likely to indicate high-risk drinking and alcohol dependence.
Measure: Alcohol Use as evaluated by the AUDIT Time: Day 1Description: The Drug Abuse Screening Test (DAST-10) is a 10-item self-reported screening test that provides a quantitative index of the degree of consequences related to drug abuse. Participants rate items yes or no, positive responses corresponding to 1 point. Items are summed up to create a score that can range from 0-10. A score of 1-2 represents risky behaviors related to drugs, 3-5 represents moderate problems, 6-8 represents substantial problems, and 9-10 represents severe problems.
Measure: Drug Use as evaluated by the DAST-10 Time: Day 1Description: The General Anxiety Disorder Scale (GAD- 7) is a 7- item self-reported screening tool that assess presence and severity of Generalized Anxiety Disorder. Participants rated frequency of problems in a 4-point Likert scale ranging from 0 (not at all) to 3 (nearly every day). Items are summed up to create a score with scores of 5, 10, and 15 being the cut-off points for mild, moderate and severe anxiety, respectively.
Measure: Anxiety as evaluated by GAD-7 Time: Day 1Description: The Center for Epidemiologic Studies Depression scale (CES-D-10) is a 10-item self-reported measure that assesses the frequency of symptoms of depression. Participants rate frequency of symptoms in a 4-point Likert scale from 0 (rare or none of the time) to 3 (most or almost all the time). Items are summed up to create a score that ranges from 0 to 30, with higher scores representing greater depressive symptoms. A score of 16 or more represents clinical depression.
Measure: Depression as assessed by CES-D-10 Time: Day 1The purpose of this study is to test the efficacy of a substance use disorder intervention delivered via a mobile application in an adult population during the COVID-19 pandemic. This study that will test the comparative efficacy of the mobile-app based substance use disorder program to reduce substance use relative to a wait list control condition, and explore between group differences on quality of life indices as well as retention and engagement during COVID-19.
Description: Range from 0-100 (no pain to worst pain imaginable)
Measure: Pain rating Time: Difference between baseline and post-treatment (8 weeks from baseline)Description: Total score between 0-27, higher scores indicate greater levels of depression
Measure: Patient Health Questionnaire-9 (PHQ-9) Time: Difference between baseline and post-treatment (8 weeks from baseline)Description: Total score between 0-21, higher scores indicate greater levels of anxiety
Measure: General Anxiety Disorder-7 (GAD-7) Time: Difference between baseline and post-treatment (8 weeks from baseline)Description: Range from 8 to 32, with higher values indicating higher satisfaction
Measure: Client Satisfaction Questionnaire (CSQ) Time: Post-treatment (8 weeks from baseline)FITSTART (Feedback Intervention Targeting Student Transitions and Risk Trajectories) is a parent-based social norms intervention that has been shown to reduce risky drinking in incoming first year students.This program uses normative feedback to correct parents overestimation of other parents negative alcohol-related parenting practices (e.g., number of drinks parents would permit their college student to consume). Theory and research suggests that correcting those common misperceptions can motivate parents to adjust their own behaviors (e.g., reducing the number of drinks they would permit), which, in turn, can impact college student drinking. Despite FITSTARTs success, the design of the program limits participation to only students who have parents who can attend on-campus orientation sessions during the summer months before the start of the Fall semester. To address this limitation and extend the previous work, the proposed randomized clinical trial (RCT) will evaluate the efficacy of an online adaptation of the FITSTART(+) PBI program. To examine the efficacy of the newly developed FITSTART+ PBI web app, the proposed RCT will use a longitudinal design to examine if students self-report drinking and related negative consequences during their first semester in college significantly differed between FITSTART+ PBI (intervention app) and a control version of the app. Self-reported drinking and consequences are expected to be lower amongst students with parents randomized to FITSTART+ PBI relative to those with parents randomized to the control app.
Description: Assesses number of drinks consumed during an average week over the past month
Measure: Change from Baseline Daily Drinking at 1 Month Time: baseline, 1 monthDescription: Assesses number of drinks consumed during an average week over the past month.
Measure: Change from Baseline Daily Drinking at 3 Months Time: baseline, 3 monthsDescription: Assesses reported frequency of negative alcohol outcomes over the past month
Measure: Change from Baseline Frequency of Alcohol Consequences at 1 Month Time: baseline, 1 monthDescription: Assesses reported frequency of negative alcohol outcomes over the past month
Measure: Change from Baseline Frequency of Alcohol Consequences at 3 Months Time: baseline, 3 monthsDescription: Assesses frequency and quantity of alcohol consumption over the past month
Measure: Change from Baseline Quantity/Frequency/Peak Alcohol Use at 1 Month Time: baseline, 1 monthDescription: Assesses frequency and quantity of alcohol consumption over the past month
Measure: Change from Baseline Quantity/Frequency/Peak Alcohol Use at 3 Months Time: baseline, 3 monthsDescription: Assesses frequency heavy episodic drinking events over the past month
Measure: Change from Baseline heavy episodic drinking at 1 Month Time: baseline, 1 monthDescription: Assesses frequency heavy episodic drinking events over the past month
Measure: Change from Baseline heavy episodic drinking at 3 Months Time: baseline, 3 monthsEvery year, alcohol use disorder (AUD) generates millions of emergency department (ED) visits and hospital admissions, costing the U.S. health sector over $90 billion. These hospital admissions are critical opportunities to start patients on addiction pharmacotherapy, but factors like medication non-adherence and post-discharge relapse contribute to frequent re-admissions. Two single-dose interventions are well suited to facilitate treatment retention and prevent re-admissions due to their prolonged, adherence-independent effects: extended-release (XR) naltrexone injection and intravenous (IV) ketamine infusion. These have not been thoroughly investigated in the hospital setting among high-utilizer, safety-net populations. Therefore, the investigators aim to: 1. Test the feasibility of randomizing hospitalized patients (n=45-60, age 18-65) with multiple AUD-related admissions to treatment with either extended-release (XR) naltrexone, intravenous (IV) ketamine, or no single-dose medication, all with enhanced linkage to care. Feasibility outcomes such as recruitment rate, patient acceptability, post-discharge follow-up rate, and adverse events will help to identify key lessons for a future comparative effectiveness study. 2. Estimate the 30-day re-admission rate for patients randomized to treatment with XR naltrexone, with IV ketamine, or no single-dose medication, all with enhanced linkage to care. The investigators hypothesize that the re-admission rate will be lower for each of the two single-dose medication groups than for the "linkage-alone" group.
Description: Binary outcome: any all-cause hospitalization ascertained by chart review (our EHR includes records from several local hospitals)
Measure: Rate (%) of 30-day hospital re-admission Time: Within 30 days of index hospital discharge. The enrollment period is 5 months.Description: Number of participants recruited per month during the enrollment period
Measure: Feasibility - recruitment rate (# per month) Time: The enrollment period is 5 monthsDescription: Percentage of patients who presented to 1 week follow-up appointment
Measure: Feasibility - follow-up rate (%) Time: The enrollment period is 5 monthsDescription: Within-subject differences in readiness to change between inpatient enrollment and outpatient follow-up.
Measure: Average within-subject difference in readiness-to-change (SOCRATES-8A score) Time: Follow-up planned to be within one week of dischargeDescription: Binary outcome: any all-cause ED visit ascertained by chart review
Measure: Rate (%) of 30-day emergency department visit Time: Within 30 days of index hospital discharge. The enrollment period is 5 months.Description: Obtained by urine EtG at outpatient follow-up
Measure: Rate (%) of urine Ethyl Glucuronide (EtG) at follow-up Time: Follow-up planned to be within one week of discharge. The enrollment period is 5 months.Description: Self reported at outpatient follow-up, ascertained by Timeline Follow-Back Method.
Measure: Rate (%) of self-reported binge drinking since discharge Time: Follow-up planned to be within one week of discharge. The enrollment period is 5 months.This is a double-blind, randomized, placebo-controlled, crossover design trial that will test the effect of pitolisant on alcohol self-administration and craving following a priming dose of alcohol. The specific objective of this proposal is to determine whether pitolisant has effects on alcohol consumption and craving
Description: Alcohol consumption will be measured by using a graduated cylinder to determine the amount of alcohol given to the subject that was not consumed. This outcome will be measured as standard drink units. A standard drink contains approximately 0.6 fluid ounces of pure alcohol.
Measure: Alcohol Consumption Time: 2.6 hoursDescription: Alcohol craving will be measured by self report with the Visual Analog Scale (VAS). The VAS is a straight line with one end meaning no alcohol craving and the other end meaning intense alcohol craving. The Participant marks a point on the line that matches their amount of alcohol craving.
Measure: Alcohol Craving Time: 2.6 hoursDescription: The Alcohol Urge questionnaire (AUQ) is an 8 item measure of self-reported urges to drink in human laboratory studies that assesses the participant's urge for an alcoholic drink at the time the questionnaire is completed, Questions are in the form of a 7-point Likert scale (from strongly disagree to strongly disagree) and participants select the extent to which they disagree or agree with the 8 statements relating to desire to drink, expectation of a desired outcome from drinking, and inability to avoid drinking if alcohol was available. Lower scores are associated with less urge for an alcoholic drink.
Measure: Alcohol Urge Time: 2.6 hoursDescription: Whether pitolisant increases the stimulant effects of a priming drink of alcohol will be assessed using the Biphasic Alcohol Effects Scale (BAES). It is a self-report, unipolar adjective rating scale that is designed to measure both stimulant and sedative effects of alcohol. It consists of fourteen items, that comprise two subscales (stimulant and sedative). Items are rated on a eleven-point scale from 0 (not at all) to 10 (extremely). The stimulant subscale can range from 0 to 70 and the sedative scale can rage from 0 to 50. Higher scores are associated with more stimulant and sedative effects, respectively.
Measure: Alcohol-induced stimulation Time: 2.6 hoursDescription: The Visual Analog Scale (VAS) will be used to assess alcohol craving during the medication exposure period. The VAS is a 10 cm straight line with one end meaning no alcohol craving and the other end meaning intense alcohol craving. Higher scores are associated with more cravings.
Measure: Alcohol craving during 4-day drug exposure Time: 4 daysDescription: Alcohol consumption during the 4 days of drug exposure will be measured using the timeline followback method
Measure: Alcohol consumption during the 4-day drug exposure Time: 4 daysThe overarching objective of the proposed project is to test the relative clinical efficacy of CBD isolate, full-spectrum CBD oil, and placebo in in reducing COVID-Induced stress, anxiety, depression, anger, and sleep disturbance.
Description: This measure is a 23-item patient-rated emotional distress symptom scale consisting of 3 sub-factors (Depression, Anxiety, and Anger). Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).
Measure: PROMIS Emotional Distress Index Time: Week 0-BaselineDescription: This measure is a 23-item patient-rated emotional distress symptom scale consisting of 3 sub-factors (Depression, Anxiety, and Anger). Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).
Measure: PROMIS Emotional Distress Index Time: Week 1-TreatmentDescription: This measure is a 23-item patient-rated emotional distress symptom scale consisting of 3 sub-factors (Depression, Anxiety, and Anger). Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).
Measure: PROMIS Emotional Distress Index Time: Week 2-TreatmentDescription: This measure is a 23-item patient-rated emotional distress symptom scale consisting of 3 sub-factors (Depression, Anxiety, and Anger). Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).
Measure: PROMIS Emotional Distress Index Time: Week 3-TreatmentDescription: This measure is a 23-item patient-rated emotional distress symptom scale consisting of 3 sub-factors (Depression, Anxiety, and Anger). Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).
Measure: PROMIS Emotional Distress Index Time: Weeks 4-TreatmentDescription: This measure is a 23-item patient-rated emotional distress symptom scale consisting of 3 sub-factors (Depression, Anxiety, and Anger). Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).
Measure: PROMIS Emotional Distress Index Time: Week 5-TreatmentDescription: This measure is a 23-item patient-rated emotional distress symptom scale consisting of 3 sub-factors (Depression, Anxiety, and Anger). Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).
Measure: PROMIS Emotional Distress Index Time: Week 6-TreatmentDescription: This measure is a 23-item patient-rated emotional distress symptom scale consisting of 3 sub-factors (Depression, Anxiety, and Anger). Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).
Measure: PROMIS Emotional Distress Index Time: Week 7-Follow-upDescription: This measure is a 23-item patient-rated emotional distress symptom scale consisting of 3 sub-factors (Depression, Anxiety, and Anger). Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).
Measure: PROMIS Emotional Distress Index Time: Week 8-Follow-upDescription: This measure is an 8-item patient-rated depression symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).
Measure: PROMIS Depression Scale Time: Week 0-BaselineDescription: This measure is an 8-item patient-rated depression symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).
Measure: PROMIS Depression Scale Time: Week 1-TreatmentDescription: This measure is an 8-item patient-rated depression symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).
Measure: PROMIS Depression Scale Time: Week 2-TreatmentDescription: This measure is an 8-item patient-rated depression symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).
Measure: PROMIS Depression Scale Time: Week 3-TreatmentDescription: This measure is an 8-item patient-rated depression symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).
Measure: PROMIS Depression Scale Time: Week 4-TreatmentDescription: This measure is an 8-item patient-rated depression symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).
Measure: PROMIS Depression Scale Time: Week 5-Follow-upDescription: This measure is an 8-item patient-rated depression symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).
Measure: PROMIS Depression Scale Time: Week 6-Follow-upDescription: This measure is an 8-item patient-rated depression symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).
Measure: PROMIS Anxiety Scale Time: Week 0 BaselineDescription: This measure is an 8-item patient-rated depression symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).
Measure: PROMIS Anxiety Scale Time: Week 1-TreatmentDescription: This measure is a 7-item patient-rated anxiety symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).
Measure: PROMIS Anxiety Scale Time: Week 2-TreatmentDescription: This measure is a 7-item patient-rated anxiety symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).
Measure: PROMIS Anxiety Scale Time: Week 3-TreatmentDescription: This measure is a 7-item patient-rated anxiety symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).
Measure: PROMIS Anxiety Scale Time: Week 4-TreatmentDescription: This measure is a 7-item patient-rated anxiety symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).
Measure: PROMIS Anxiety Scale Time: Week 5-Follow-upDescription: This measure is a 7-item patient-rated anxiety symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).
Measure: PROMIS Anxiety Scale Time: Week 6-Follow-upDescription: This measure is an 8-item patient-rated anger symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).
Measure: PROMIS Anger Scale Time: Week 0 BaselineDescription: This measure is an 8-item patient-rated anger symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).
Measure: PROMIS Anger Scale Time: Week 1 TreatmentDescription: This measure is an 8-item patient-rated anger symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).
Measure: PROMIS Anger Scale Time: Week 2 TreatmentDescription: This measure is an 8-item patient-rated anger symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).
Measure: PROMIS Anger Scale Time: Week 3 TreatmentDescription: This measure is an 8-item patient-rated anger symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).
Measure: PROMIS Anger Scale Time: Week 4 TreatmentDescription: This measure is an 8-item patient-rated anger symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).
Measure: PROMIS Anger Scale Time: Week 5 Follow-upDescription: This measure is an 8-item patient-rated anger symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).
Measure: PROMIS Anger Scale Time: Week 6 Follow-upDescription: This measure is an 8-item patient-rated index of alcohol-related problems. Each item is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).
Measure: PROMIS Alcohol Negative Consequences Scale Time: Week 0 BaselineDescription: This measure is an 8-item patient-rated index of alcohol-related problems. Each item is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).
Measure: PROMIS Alcohol Negative Consequences Scale Time: Week 1 TreatmentDescription: This measure is an 8-item patient-rated index of alcohol-related problems. Each item is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).
Measure: PROMIS Alcohol Negative Consequences Scale Time: Week 2 TreatmentDescription: This measure is an 8-item patient-rated index of alcohol-related problems. Each item is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).
Measure: PROMIS Alcohol Negative Consequences Scale Time: Week 3 TreatmentDescription: This measure is an 8-item patient-rated index of substance use severity. Each item is rated over a 7-day period on a 5-point scale ranging from 1 (Not at all) to 5 (Almost Always).
Measure: PROMIS Alcohol Negative Consequences Scale Time: Week 4 TreatmentDescription: This measure is an 8-item patient-rated index of substance use severity. Each item is rated over a 7-day period on a 5-point scale ranging from 1 (Not at all) to 5 (Almost Always).
Measure: PROMIS Alcohol Negative Consequences Scale Time: Week 5 Follow-upDescription: This measure is an 8-item patient-rated index of substance use severity. Each item is rated over a 7-day period on a 5-point scale ranging from 1 (Not at all) to 5 (Almost Always).
Measure: PROMIS Alcohol Negative Consequences Scale Time: Week 6 Follow-upDescription: This measure is an 8-item patient-rated index of sleep disturbance. Each item is rated over a 7-day period on a 5-point scale ranging from 1 (Not at all) to 5 (Very Much).
Measure: PROMIS Sleep Disturbance Scale Time: Week 0 BaselineDescription: This measure is an 8-item patient-rated index of sleep disturbance. Each item is rated over a 7-day period on a 5-point scale ranging from 1 (Not at all) to 5 (Very Much).
Measure: PROMIS Sleep Disturbance Scale Time: Week 1 TreatmentDescription: This measure is an 8-item patient-rated index of sleep disturbance. Each item is rated over a 7-day period on a 5-point scale ranging from 1 (Not at all) to 5 (Very Much).
Measure: PROMIS Sleep Disturbance Scale Time: Week 2 TreatmentDescription: This measure is an 8-item patient-rated index of sleep disturbance. Each item is rated over a 7-day period on a 5-point scale ranging from 1 (Not at all) to 5 (Very Much).
Measure: PROMIS Sleep Disturbance Scale Time: Week 3 TreatmentDescription: This measure is an 8-item patient-rated index of sleep disturbance. Each item is rated over a 7-day period on a 5-point scale ranging from 1 (Not at all) to 5 (Very Much).
Measure: PROMIS Sleep Disturbance Scale Time: Week 4 TreatmentDescription: This measure is an 8-item patient-rated index of sleep disturbance. Each item is rated over a 7-day period on a 5-point scale ranging from 1 (Not at all) to 5 (Very Much).
Measure: PROMIS Sleep Disturbance Scale Time: Week 5 Follow-upDescription: This measure is an 8-item patient-rated index of sleep disturbance. Each item is rated over a 7-day period on a 5-point scale ranging from 1 (Not at all) to 5 (Very Much).
Measure: PROMIS Sleep Disturbance Scale Time: Week 6 Follow-upDescription: This measure is a 12-item author-constructed patient-rated index of COVID-19 Coping Self-Efficacy
Measure: COVID-19 Coping Self-Efficacy Time: Week 0 BaselineDescription: This measure is a 12-item author-constructed patient-rated index of COVID-19 Coping Self-Efficacy
Measure: COVID-19 Coping Self-Efficacy Time: Week 1 TreatmentDescription: This measure is a 12-item author-constructed patient-rated index of COVID-19 Coping Self-Efficacy
Measure: COVID-19 Coping Self-Efficacy Time: Week 2 TreatmentDescription: This measure is a 12-item author-constructed patient-rated index of COVID-19 Coping Self-Efficacy
Measure: COVID-19 Coping Self-Efficacy Time: Week 3 TreatmentDescription: This measure is a 12-item author-constructed patient-rated index of COVID-19 Coping Self-Efficacy
Measure: COVID-19 Coping Self-Efficacy Time: Week 4 TreatmentDescription: This measure is a 12-item author-constructed patient-rated index of COVID-19 Coping Self-Efficacy
Measure: COVID-19 Coping Self-Efficacy Time: Week 5 Follow-upDescription: This measure is a 12-item author-constructed patient-rated index of COVID-19 Coping Self-Efficacy
Measure: COVID-19 Coping Self-Efficacy Time: Week 6 Follow-upAlphabetical listing of all HPO terms. Navigate: Correlations Clinical Trials
Data processed on December 13, 2020.
An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.
Drug Reports MeSH Reports HPO Reports