SNPMiner Trials (Home Page)
Report for SNP rs10994336
Developed by Shray Alag, 2020.
SNP Clinical Trial Gene
There is one clinical trial.
Clinical Trials
1 Ion Channel Genetic Biomarkers: Diagnostic Capabilities in the Assessment of Bipolar Disorder
Genotype 164 adults to evaluate six selected single nucleotide polymorphisms (SNPs) (rs1006737, rs10994336, rs10994133, rs2238071, rs1051375, rs1024582) for use as a genetic biomarker to differentiate between bipolar depression and unipolar depression.
NCT03572426 Bipolar Disorder Other: genotyping all subjects MeSH:Bipolar Disorder
HPO:Bipolar affective disorder Mania
Ion Channel Genetic Biomarkers: Diagnostic Capabilities in the Assessment of Bipolar Disorder Genotype 164 adults to evaluate six selected single nucleotide polymorphisms (SNPs) (rs1006737, rs10994336, rs10994133, rs2238071, rs1051375, rs1024582) for use as a genetic biomarker to differentiate between bipolar depression and unipolar depression.
Genetic risk score of selected SNPsrs1006737, rs10994336, rs10994133, rs2238071, rs1051375, rs1024582.
Primary Outcomes
Description: Logistic regression will be used to examine a genetic risk score using a risk allele count as the independent variable, with a diagnosis of BD versus MDD versus those with no mood diagnosis as the dependent variable.
Measure: Logistic Regression Time: 1 yearSecondary Outcomes
Description: Genetic risk score of selected SNPsrs1006737, rs10994336, rs10994133, rs2238071, rs1051375, rs1024582
Measure: Genetic Risk Score Time: 1 yearDescription: Positive family history of bipolar disorder in a first degree relative
Measure: Family History Time: 1 yearDescription: 0-10 item scale assessing for adversity experienced during childhood
Measure: Adverse Childhood Experiences Scale Time: 1 year