SNPMiner Trials (Home Page)
Report for SNP rs1800629
Developed by Shray Alag, 2020.
SNP Clinical Trial Gene
There is one clinical trial.
Clinical Trials
1 Polymorphisms and Efficiency of Caffeine on Performances During Total Sleep Deprivation un Healthy Subject. Multicentric, Versus Placebo, Randomised, Cross Over, Double Blind Study
In this multicentric controlled study, we aims to evaluate effect of caffeine on mental performances during a sleep deprivation protocol. Genetic polymorphisms are considered as a covariable.
NCT03859882 Sleep Caffeine Polymorphism Other: Sleep deprivation MeSH:Sleep Deprivation
This study, under conditions of total sleep deprivation in the laboratory (40 hours of continuous awakening), examine the cross-influence of two polymorphisms (ADORA2A: rs5751876 and TNF-alpha: rs1800629) on the sensitivity to caffeine and on the degradation of attentional performances.
Primary Outcomes
Description: Speed at the Psychomotor vigilance test test
Measure: Psychomotor vigilance test Speed Time: Change from Baseline Psychomotor vigilance test Speed at day 2 after 24 hours awakingSecondary Outcomes
Description: Number of errors at executive performance test
Measure: Cognitive performance Time: Change from Baseline at day 2 after 25 hours awakingDescription: Power at the force-velocity test
Measure: Force -velocity Time: Change from Baseline at day 2 after 32 hours awaking