SNPMiner Trials (Home Page)
Report for SNP rs1800592
Developed by Shray Alag, 2020.
SNP Clinical Trial Gene
There is one clinical trial.
Clinical Trials
1 Development and Clinical Application of Bitter Melon Seed Oil as a Functional Food for Treating Obesity and Hepatic Steatosis
To investigate the metabolic benefits of bitter melon seed oil (BMSO), overweight or obese healthy Taiwanese adults (n=60) were randomly assigned to receive capsules containing either olive oil (OO; placebo) or BMSO at 4.5 g/d dose for 12 week. Across intervention period, body weight, BMI, waist-to-hip ratio, and body fat mass were measured. Blood were collected before and after intervention for measurements of blood lipid and inflammatory cytokines. The anti-obesity effect of BMSO was further assessed by stratification of participants according to UCP1 rs1800592 polymorphism.
NCT03785821 Weight Gain Dietary Supplement: BMSO Dietary Supplement: OO MeSH:Weight Gain
HPO:Increased body weight
The anti-obesity effect of BMSO was further assessed by stratification of participants according to UCP1 rs1800592 polymorphism.
Considering UCP-1 played a pivotal role in anti-adiposity function of BMSO as demonstrated in animal studies, the anti-obesity effect of BMSO was further assessed according to UCP1 rs1800592 polymorphism.
Primary Outcomes
Description: Changes at intervention for 4,8 and 12 week
Measure: Weight gain Time: 12 weekSecondary Outcomes
Description: Changes at intervention for 4,8 and 12 week
Measure: BMI Time: 12 wkDescription: Changes at intervention for 4,8 and 12 week
Measure: waist-to hip ratio Time: 12 wkDescription: Changes at intervention for 4,8 and 12 week
Measure: body fat mass Time: 12 wk