SNPMiner Trials by Shray Alag


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Report for SNP rs2043211

Developed by Shray Alag, 2020.
SNP Clinical Trial Gene

There is one clinical trial.

Clinical Trials


1 Quantification of NLRP3 (rs4612666) and CARD8 Gene (rs2043211) in Subgingival Plaque and Blood Samples of Generalized Chronic Periodontitis Subjects With and Without Coronary Heart Disease

Quantification of NLRP3 (rs4612666) and CARD8 (rs20432111) will be analysed in the subgingival plaque and blood samples of generalized chronic periodontitis with and without coronary heart disease. The demographic and the periodontal parameters were assessed and correlated with the quantification of NLRP3 (rs4612666) and CARD8 (rs2043211) was analysed with RT-PCR

NCT04127487 Periodontal Diseases Coronary Artery Disease
MeSH:Periodontitis Chronic Periodontitis Periodontal Diseases Coronary Artery Disease
HPO:Coronary artery atherosclerosis Periodontitis

Quantification of NLRP3 (rs4612666) and CARD8 Gene (rs2043211) in Subgingival Plaque and Blood Samples of Generalized Chronic Periodontitis Subjects With and Without Coronary Heart Disease.

Quantification of NLRP3 (rs4612666) and CARD8 Gene (rs2043211) in Generalized Chronic Periodontitis Subjects Quantification of NLRP3 (rs4612666) and CARD8 (rs20432111) will be analysed in the subgingival plaque and blood samples of generalized chronic periodontitis with and without coronary heart disease.

The demographic and the periodontal parameters were assessed and correlated with the quantification of NLRP3 (rs4612666) and CARD8 (rs2043211) was analysed with RT-PCR Expression of NLRP3 (rs4612666) and CARD8 (rs20432111) gene.

To determine the expression of NLRP3 (rs4612666) and CARD8 gene (rs2043211) polymorphisms in subgingival tissue samples of generalised chronic gingivitis periodontitis subjects with and without coronary artery disease.

To correlate the demographic variables and periodontal parameters and the expression of NLRP3 (rs4612666) and CARD8 (rs2043211) gene polymorphisms in generalised chronic periodontitis patients with coronary artery disease and compare them with systemically healthy chronic periodontitis patients

Primary Outcomes

Description: Expression of NLRP3 (rs4612666) and CARD8 (rs20432111) gene using RT-PCR

Measure: Expression of NLRP3 (rs4612666) and CARD8 (rs20432111) gene

Time: 12 months

Secondary Outcomes

Description: Quantification of NLRP3 (rs4612666) and CARD8 (rs20432111) gene using RT-PCR

Measure: Quantification of NLRP3 (rs4612666) and CARD8 (rs20432111) gene

Time: 12 months


HPO Nodes