There is one clinical trial.
The investigators assume that REST gene polymorphism affects REST protein concentration, and REST protein concentration in peripheral blood is related to cognitive function and hippocampus. In this current study, REST protein content and gene polymorphism will be obtained in peripheral blood in AD and normal control. The effect of REST gene polymorphism on REST protein concentration will be discovered.The relationship between REST protein concentration and cognitive function will be found, as well as the relationship between REST protein concentration and hippocampus.
Rate of Gene polymorphism in rs2227902 and rs3796529.. Verifying the value of REST gene polymorphism as an early markers of Alzheimer's Disease.
Description: Verifying the value of REST gene polymorphism as an early markers of Alzheimer's Disease
Measure: Rate of Gene polymorphism in rs2227902 and rs3796529. Time: baselineDescription: Verifying the value of REST protein detection as an early markers of Alzheimer's Disease
Measure: Concentration of REST protein Time: baseline