There is one clinical trial.
Studies have shown that the effect of fat mass and obesity-associated (FTO) gene on obesity is modulated by lifestyle factors. Hence, we aimed to determine whether two single nucleotide polymorphisms (SNPs) in the FTO gene are associated with obesity and to assess whether these associations were modified by lifestyle factors. The study included 200 obese and 200 non-obese individuals from Turkey. Our study suggests that the effect of the SNPs on obesity traits is likely to be influenced by lifestyle factors in this Turkish population.
FTO SNPs rs9939609 and rs10163409.
Description: FTO SNPs rs9939609 and rs10163409
Measure: Genetic analysis of two SNPs at FTO gene Time: up to 36 weeksDescription: Body mass index, waist circumference, hip circumference, body composition
Measure: Anthropometric measurements Time: up to 36 weeksDescription: lipid profile, glucose, insulin, adiponectin
Measure: Biochemical measurements Time: up to 36 weeks