Covid 19 Research using Clinical Trials (Home Page)
Report for D002386: Cataract NIH
(Synonyms: Cataract)
Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation
Correlated Drug Terms (3)
| Name (Synonyms) | Correlation | |
|---|---|---|
| drug2534 | Tocilizumab Injection Wiki | 0.71 |
| drug733 | Deferoxamine Wiki | 0.71 |
| drug1978 | Questionnaire Wiki | 0.21 |
Correlated MeSH Terms (0)
| Name (Synonyms) | Correlation |
|---|
There is one clinical trial.
Clinical Trials
1 Assessment of Vision-related Quality of Life (VRQOL) in Cataract Patients During the COVID-19 Pandemic
The aim of this questionnaire survey is to evaluate the improvement in vision-related quality of life before and after cataract surgery using the National Eye Institute Visual Function Questionnaire 25 and the delay of improvement in the COVID-19 pandemic.
NCT04468308 Senile Cataract Other: Questionnaire MeSH:Cataract
HPO:Cataract Membranous cataract
Primary Outcomes
Description: Extent of improvement of vision-related qualitiy of life due to cataract surgery measured with the National Eye Institut Visual Function Questionnaire 25.
Measure: Improvement Vision-related quality of life Time: 3 months
Secondary Outcomes
Description: Delay of improvement of vision-related qualitiy of life in the COVID-19 pandemic measured in days between the originally scheduled operation and the actual operation date
Measure: Delay of Vision-related quality of life Time: 3 months
Description: Visual acuity difference between visual acuity at the time of indication for cataract surgery, on the day of surgery and one month postoperatively.
Measure: Visual acuity Time: 1 month
HPO Nodes
HP:0000518: Cataract
Genes 987
BAP1 SDCCAG8 MTAP KCNJ13 KCNAB2 POMT1 ARHGAP31 COX1 PTEN REEP6 RAB3GAP1 KIAA1549 ERCC3 MEFV CLRN1 BRIP1 CRYGD COL2A1 MED25 CRYGD COL2A1 PCYT1A SALL4 YAP1 EYS KCNH1 OPA3 GJA1 ADAMTS18 RDH12 RAB3GAP2 PEX1 GLA WDR35 CC2D2A CCR1 TRNL1 PTCH1 SEC23A GALK1 GJA1 USH1C FAM111A FTL TRNK RNF113A TFAP2A GSR SMCHD1 XRCC4 RPGRIP1 SLC7A14 GNAS KCNH1 PHYH PEX12 SLX4 PEX10 ESCO2 PTCH2 OCLN AGBL5 WRN POMGNT1 BCOR SUFU AGA RAD21 C4A COL2A1 BUB3 CEP290 ERCC2 PAX6 ALDH18A1 RPGRIP1 BEST1 KCNJ13 COL11A1 SALL2 FANCA RET LAMB1 CRYGB TBR1 PEX12 TRAPPC11 CYP1B1 PEX7 BRF1 VIM FAR1 COG4 RAB18 GEMIN4 PHGDH ALDH18A1 GJB6 IQCB1 XRCC2 CRB1 TBC1D20 TMEM67 KRT71 PTPN22 ABHD12 TRAPPC11 OCRL EBP SRD5A3 ERCC2 FAM126A OFD1 ATAD3A TINF2 NPHP1 USH1G ARL6 GTF2IRD1 CLPB UFD1 FANCB CDHR1 FAS UNC45B HNRNPA2B1 WT1 PIGY COL18A1 CEP57 CNGA1 FANCM DHDDS RAB3GAP1 POLG ERCC6 NF2 RNF13 TONSL TRNW EP300 SUMF1 ALX3 B3GALNT2 POMGNT1 NEK2 ITPA POMT1 MAK PHF6 CLIP2 COL4A3 ALX3 ERCC2 BBS2 COMT POMT2 WDPCP FKTN PEX5 PLK4 PEX11B CRPPA SIL1 DNMT1 PEX26 IL23R TULP1 SMAD4 FOXE3 ERCC3 ERAP1 C8ORF37 PEX5 NEU1 NOTCH1 DMPK PTH CEP78 HIRA DKC1 NR2E3 PEX19 AKT1 CERKL CREBBP MMP1 SEC23B FYCO1 DYNC2I2 HBB FKTN CRPPA CC2D2A GSN AKT1 TBC1D24 GJA3 TERT HLA-B RAB18 WNT3 ADAMTS10 PEX2 TRNL1 COL18A1 MAD2L2 DDB2 ARSL IQCB1 ANAPC1 CRYBA4 PRPF4 BCS1L GUCY2D DYNC2H1 FBN1 TUB VSX2 PEX13 SMARCE1 TTC8 KIAA1109 RP9 XYLT2 KMT2A BDNF PTEN MKS1 ARID2 PAH RHO HGSNAT ALX1 ERCC4 FLVCR1 CTC1 DNM1L ND6 KIF1B ARHGEF18 PMM2 KRT6A RP1 GNAS RECQL4 SMAD3 HDAC8 PALB2 ALG2 PEX16 SLC33A1 OTX2 SIX6 ND1 PAH SDHD RP2 PIK3CA DHCR7 RAB3GAP1 OAT CHRDL1 MAF VHL SC5D GBA2 PEX16 NPHP3 FKRP TRAPPC11 SMARCD1 NUP188 ERCC5 RPS6KA3 ALMS1 GUCA1B PDE6G TFAP2A CCDC28B ZNF335 HSF4 B3GLCT PRDM16 ERCC1 COX7B IDH3B MFRP B4GALNT1 POMGNT2 LMNA KRT81 PEX13 GDNF ALDOB RREB1 ALDH18A1 PDE6B PEX11B GJB6 TRNE ZNF408 PEX7 LOXL1 NACC1 FKRP GTF2H5 PEX3 TMEM216 PNPT1 FAM111A HTRA2 PAX6 PEX19 PEX1 SPATA7 FKTN KCNJ13 POMK TONSL RPE65 UBA5 COL4A3 CYTB GNAS IKBKG POMGNT1 DYNC2I1 SMARCB1 MYO7A EED BFSP2 BCOR RPGR FANCD2 LARGE1 NEU1 ERCC5 GNPAT IKBKG POMT1 POLG MAB21L2 PLCG2 DMPK PEX2 TWNK POLG2 DGUOK NAA10 BAZ1B PIK3CA CENPF PTH1R CYP7B1 BCOR POMT2 GMPPB COL4A5 EBP PCDH15 KCTD1 SDHD ACTB GP1BB POMT1 MIP CLPB MIPEP MVK CASK ENTPD1 ARID1B RAD51 GALT NPHP4 JAG1 ZNF408 COL4A4 REEP6 COL9A3 SLC25A4 PEX11B EYS B4GALNT1 SRD5A3 LIG4 CRX RGR ERCC6 ERCC3 MED25 EPG5 PTEN NR2E3 APC PEX5 ESCO2 NAGA ZBTB20 NHS SEC23A FGF5 AIRE AIRE STAT4 KLHL7 B3GALNT2 CBS TCOF1 FH RPGRIP1 AKT1 CEP164 CRYGC ADAMTSL4 ACTB RAD51C CDH23 BTNL2 FOXC2 OAT SDHB BBS2 ERCC2 TBX1 TBC1D24 USH2A GMPPB RP2 SETD5 JAM3 IFT172 KCNA4 BMP4 KIF11 FOXC1 BBS1 NMNAT1 FAM161A CRYGS RPE65 CRYAB PARN EOGT ALDH6A1 SLC40A1 ATP6V1A PEX10 SLC16A12 COL11A1 KDSR FBN1 VCP ARL3 LRAT PEX7 GABRD TGFBI POMT2 PAX6 NACC1 GALT PAX6 WDR19 TDRD7 MERTK P3H2 HLA-DRB1 COL2A1 DPAGT1 COL11A1 POMGNT1 IARS2 COL11A1 FAS CNGB3 WDR19 POMT2 BUB1B FTL HSPG2 CRX C8ORF37 GNAS SUFU CRB1 RD3 LIMK1 MPLKIP FANCL AFF4 PRPF6 IMPG2 WRN AMMECR1 ARL6 CYSLTR2 PEX7 LARGE1 KIF11 IFT140 ELN IL12A-AS1 LSS CEP55 GMPPB RRM2B CRYBA1 ATP6V1B2 WRAP53 TRNC ARL3 GFER ALDH18A1 PNPT1 SALL4 ZNF408 ALG2 PAX6 FKTN TRNK XPC RHOA SOX11 KANSL1 AIPL1 KLRC4 CRYBA2 ERCC8 PEX6 PHGDH AGK TELO2 USH2A BFSP1 COL2A1 POLR1D AGK GJA1 LIPH TMTC3 GNAS POLG GNAQ MYMK DOCK6 LRP2 MYSM1 FLI1 MAN2B1 WFS1 MIR140 PEX1 NOD2 ARVCF DLL4 PITX2 CRX COL9A2 INVS PRUNE1 COL2A1 TRIM44 B9D1 SMCHD1 CRYGC SKI RBP3 COL4A1 CNGB1 SDHC RBPJ ZNF513 SLC25A4 ABHD5 FIBP SCAPER TRNQ B3GLCT IFT140 GMPPB UBE2T RDH12 PXDN CLN3 LMX1B MAF HNRNPDL SMC1A PEX1 ADGRV1 PEX16 SLC2A1 TWNK XYLT2 PEX11B CEP290 VLDLR PEX14 GNA11 PEX5 MYH9 IL12A PEX19 RFC2 ERCC4 INPP5K SIL1 CFAP410 CDH11 FAR1 ADAMTS10 DHX38 GTPBP2 LCA5 GJA1 KIZ PEX12 PAX6 KRT16 CRYAB PRPF8 RAB3GAP2 HMX1 GALK1 MSMO1 CRYAA PMPCA POMK KRT86 PEX6 NHS JMJD1C PEX13 TMEM70 LRP5 GFER TBC1D20 ABCA4 ERCC6 TRNS2 PEX5 FLNA FGF3 BRCA2 RXYLT1 NRL GJA8 GJB4 NSUN2 POLR1C WT1 GJB3 LMNA PROM1 PIK3R1 BAP1 BRCA1 BUB1B CSPP1 KRT25 WDR81 ZEB2 EPG5 IMPDH1 TCTN2 SOX4 CPAMD8 TARS1 POMT2 ALMS1 ETFDH PRCD TGM3 PNPLA6 ATP8A2 STX16 MVK NDP VCAN FOXE3 ARID1A CA4 PIK3C2A RAB3GAP2 POLR3A CPT2 FZD4 BEST1 NR2E3 PTCH2 TBX1 B4GAT1 FBN1 RECQL4 ERCC2 BUB1 CRYAA DAG1 YAP1 PCARE TKFC TRAF3IP1 USP9X SEC24C ALDH18A1 PEX3 MAX MAF SLC2A1 TMEM107 PTCH1 DOCK6 COL7A1 PEX2 CRYBB2 RB1 SLC25A4 POMT1 CLRN1 AHR LRAT ALG8 FKRP OPA1 AMER1 USP45 PAX2 RSPO2 FANCE PHGDH HNRNPA1 SMARCC2 NOP10 IFT80 RFWD3 SPRTN SHROOM4 ZBTB20 FTL RAB3GAP2 CRB1 GCNT2 TMEM127 NIPBL INPP5K NF2 COG4 GTF2H5 RBP3 GMPPB TOPORS PHYH CAV1 NOD2 DSG4 HSPG2 PEX26 CHMP4B PHGDH SCAPER PEX5 ARL2BP TUBG1 CRYBB1 CTDP1 INTS1 MYO7A ARL2BP COL11A1 CRYBB3 PEX10 FANCF ADNP LONP1 PEX26 LEMD2 ITM2B TRIP13 COX3 MIR184 EPHA2 ATOH7 MAN2B1 PRPF3 RAB3GAP2 WHRN FIG4 SMC3 GTF2E2 FAM126A PITX3 CEP290 ALDH18A1 FANCG LRP5 RERE LARGE1 TRNV PDZD7 CA8 KRT74 SALL1 INPP5E CYP27A1 FANCI TWNK NEK9 PEX13 POMGNT1 UBAC2 POLG LMX1B CYP7B1 APC MORC2 CRYBB1 TRIM44 UBE2A EBP ERCC5 FKRP LPAR6 IMPDH1 ANO10 RTEL1 PTEN VHL ABCA12 PEX26 SMARCA4 ALDH18A1 ABHD5 NDP AHI1 RPGRIP1L ETFA SAG NDUFB11 PEX2 CDH23 PLOD3 TLR4 SLC25A13 HLA-A CNBP NDP HARS1 RIC1 FAM111B DPF2 MAF LOXL3 SPATA7 NOTCH2 ARSG WNT3 SLC4A4 DACT1 CRYAB TWNK PEX3 SF3B1 RPE65 ETFB AGK KLLN TUBB2B PEX14 GDF6 SC5D COX2 TRNF GTF2I XPA GNAS IMPDH1 LRP4 DHX38 OCRL IDH3A KCNN3 DHCR7 FKRP KRT83 B9D2 IL10 RHO MIR204 PEX6 NPM1 COL4A1 RP9 COL9A1 PTCH1 LTBP2 IARS2 LARGE1 VPS13A RLBP1 CRYBA4 PQBP1 TKFC VLDLR PAX6 EBP COL7A1 CNBP GJA8 FBN1 AFF4 LIM2 LRP5 BBIP1 TERC NHS TRPV4 RS1 POMK LONP1 KRT17 CYP27A1 TUBGCP6 ND5 CTDP1 ABCA2 FIG4 FANCC FBXL4 PRPH2 ERCC2 ROM1 DAG1 GUCY2D TBL2 CIB2 SDHB MAP2K2 OPA3 PEX14 MAFA HCCS FLNB SEMA4A AP1S1 PEX3 RDH11 TULP1 SNRNP200 IFT88 VAC14 SIPA1L3 ESPN PEX16 GBA2 USF3 OFD1 TULP1 KCTD1 FSCN2 TRNS1 FKTN ELP4 USP9X NHP2 B3GALNT2 TMEM231 PEX16 PEX3 PITX3 IMPG2 PSAT1 SMAD4 TKT FOXC1 USB1 PRPF31 KRT6B ADAMTSL4 DKC1 TRNS2 PDE6A USP8 WDR73 CRYBB2 COL2A1 Protein Mutations 0
SNP 0
Primary Outcomes
Description: Extent of improvement of vision-related qualitiy of life due to cataract surgery measured with the National Eye Institut Visual Function Questionnaire 25.
Measure: Improvement Vision-related quality of life Time: 3 monthsSecondary Outcomes
Description: Delay of improvement of vision-related qualitiy of life in the COVID-19 pandemic measured in days between the originally scheduled operation and the actual operation date
Measure: Delay of Vision-related quality of life Time: 3 monthsDescription: Visual acuity difference between visual acuity at the time of indication for cataract surgery, on the day of surgery and one month postoperatively.
Measure: Visual acuity Time: 1 month