Covid 19 Research using Clinical Trials (Home Page)
Report for D059352: Musculoskeletal Pain NIH
(Synonyms: Musculoskeletal Pain)
Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation
Correlated Drug Terms (4)
| Name (Synonyms) | Correlation | |
|---|---|---|
| drug2688 | Web-based self-report questionnaires Wiki | 0.50 |
| drug957 | Focus Group Interviews Wiki | 0.50 |
| drug1908 | Primary care Wiki | 0.50 |
| drug2451 | Tele-yoga therapy Wiki | 0.50 |
Correlated MeSH Terms (0)
| Name (Synonyms) | Correlation |
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Correlated HPO Terms (0)
| Name (Synonyms) | Correlation |
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There are 4 clinical trials
Clinical Trials
1 Effects of Chronic Pain, Dyspnea, and Physical Activity Promotion on Functional Connectivity of the Brain in COPD
Persons with COPD have both chronic musculoskeletal pain and dyspnea that require accurate diagnosis and treatment, ultimately to optimize functional status. The investigators propose to use advanced neuroimaging techniques to understand central mechanisms of chronic pain, dyspnea, and physical activity promotion in COPD. The investigators' novel proposal to correlate subjective symptoms (chronic pain and dyspnea) with an objective central biomarker (resting state functional connectivity) and examine their changes in response to a non-pharmacological, non-addictive physical activity intervention will personalize the care of Veterans with COPD.
NCT04291131 COPD Chronic Musculoskeletal Pain MeSH:Musculoskeletal Pain
Primary Outcomes
Description: Cortical thickness will be measured by brain MRIs that will assess functional connectivity and structural variables. Cortical thickness will be reported in millimeters.
Measure: Cortical thickness Time: 3 monthsOther Outcomes
Description: Pain intensity will be measured with the Brief Pain Index.
Measure: Pain Intensity Time: 3 monthsDescription: Dyspnea will be measured with the modified Medical Research Council scale
Measure: Dyspnea Time: 3 months2 Evaluate the Working Environments of Individuals Working From Home During Covid-19 Outbreak
The study aims to evaluate the working environments of individuals working from home during the covid-19 outbreak and the effect of the working environments on their musculoskeletal system. The study will include 500 people between the ages of 18-65 who works from home (works in the office before isolation) as a part of Covid-19 isolation measure. The working environment of the individuals participating in the study will be evaluated with The Rapid Office Strain Assessment (ROSA). Musculoskeletal symptoms will be analysed by using the Standardised Nordic Questionnaries (NMQ). Pain will be analysed by using Visual Analogue Scale (VAS)
NCT04342208 Musculoskeletal Pain MeSH:Musculoskeletal Pain
Primary Outcomes
Description: The working environment of the individuals participating in the study will be evaluated with The Rapid Office Strain Assessment (ROSA).
Measure: The Rapid Office Strain Assessment (ROSA) Time: 30 minutesSecondary Outcomes
Description: The NMQ can be used as a questionnaire or as a structured interview
Measure: The Standardised Nordic Questionnaries (NMQ) Time: 15 minutesOther Outcomes
Description: Pain will be analysed by using Visual Analogue Scale (VAS)
Measure: Visual Analog Scale (VAS) Time: 2 minutes3 Sustainable UNiversity Life (SUN): Mental Illness and Pain Conditions Among Students - a Cohort Study to Identify Modifiable Risk and Prognostic Factors
In 2017, Socialstyrelsen reported that mental ill-health in young adults had increased by almost 70% in the previous10 years. A 2014 report showed that 5% of men and 11% of women 18-24 years were diagnosed with depression or anxiety in Stockholm County. Furthermore, 41% of women 21-24 years have self reported psychological distress. Regarding pain, 28% of men and 36% of women 16-24 years have disabling neck pain. Little is known about the etiology and prognosis of poor mental health in university students. The aim is to advance knowledge about the etiology of depression, anxiety, stress and pain in undergraduate university students. The investigators will study a cohort of students at full-year programs at universities in the Stockholm area. Primary research questions are whether modifiable factors such as sleep quality, lifestyle, screen time and work environment are independent risk factors for incident episodes or unfavorable trajectories of depression, anxiety and pain in men and women? To be able to answer these research questions we designed a prospective cohort study targeting 5000 university students.
NCT04465435 Mental Health Issue Musculoskeletal Pain Other: Web-based self-report questionnaires Other: Focus Group Interviews MeSH:Musculoskeletal Pain
Primary Outcomes
Description: Repeated measures with web-based questionnaires, 5 times (every 3 months), over one year. Outcome measures: Musculoskeletal pain will be measured with the The Nordic Musculoskeletal Questionnaire (NMQ). The NMQ measure musculoskeletal symptoms, and pain intensity in nine body areas: neck, shoulder, elbow, wrists/hands, upper back, lower back, hips/thighs/buttocks, knees, ankle/feet. The questions were modified to assess previous month rather than the previous 12 months as per the original NMQ. No symptoms = a pain score of 0, while the participants who report musculoskeletal symptoms also report average pain intensity over the last month, on a scale from 0 (no complaints), to 9 (pain 'worst possible'). Weekly text messages measure levels of pain.
Measure: Pain Time: 2019-2022Description: Repeated measures with web-based questionnaires, 5 times (every 3 months), over one year. Outcome measures: Depression Anxiety Stress Scale-21(DASS-21). DASS-21 includes three subscales (range 0-3, score 0-63, higher scores = more symptoms) to measure depression, anxiety and stress symptoms in nonclinical populations. Weekly text messages measure levels anxiety and depression.
Measure: Mental health problems Time: 2019-2022Secondary Outcomes
Description: Web-based questionnaires comparing students entering the study before the Covid-19 pandemic and after. Outcome measures: Musculoskeletal pain will be measured with the The Nordic Musculoskeletal Questionnaire (NMQ). The NMQ measure musculoskeletal symptoms, and pain intensity in nine body areas: neck, shoulder, elbow, wrists/hands, upper back, lower back, hips/thighs/buttocks, knees, ankle/feet. The questions were modified to assess previous month rather than the previous 12 months as per the original NMQ. No symptoms = a pain score of 0, while the participants who report musculoskeletal symptoms also report average pain intensity over the last month, on a scale from 0 (no complaints), to 9 (pain 'worst possible'). Weekly text messages measure levels of pain.
Measure: Pain related to the Covid-19 pandemic. Time: 2019-2020Description: Web-based questionnaires comparing students entering the study before the Covid-19 pandemic and after. Outcome measures: Depression Anxiety Stress Scale-21(DASS-21). DASS-21 (3 subscales, range 0-3, score 0-63, higher scores = more symptoms) to measure depression, anxiety and stress symptoms in nonclinical populations. Weekly text messages measure levels of anxiety and depression.
Measure: Mental health problems related to the Covid-19 pandemic. Time: 2019-20204 Effect of Tele-Yoga Therapy on Patients With Chronic Musculoskeletal Pain During Covid-19 Lockdown: Randomized Clinical Trial
Covid-19 outbreak and lockdown measures raised significant concerns over clinical management of chronic pain patients around the world. Patients with chronic musculoskeletal pain (CMSP) are at high risk of physical disability, psychological distress, and poor quality of life. Analgesic medications were main management during lockdown, but opioid-related concerns have prompted to find immediate alternatives. Present study was undertaken to determine whether patients randomized to tele-yoga therapy would experience less pain, disability and improved global health, adherence and satisfaction, compared with patients assigned to usual care.
NCT04466605 Chronic Musculoskeletal Pain Other: Tele-yoga therapy Other: Primary care MeSH:Musculoskeletal Pain
Primary Outcomes
Description: Pain was assessed using the Brief Pain Inventory (BPI), which rates the severity of pain on 4 items (current, worst, least, and average pain in past week)
Measure: Severity of pain Time: From baseline to 6-week post interventionDescription: Interference of pain in 7 areas (mood, physical activity, work, social activity, relations with others, sleep, enjoyment of life) were reported using BPI
Measure: Interference of pain Time: From baseline to 6-week post interventionSecondary Outcomes
Description: 7-point global rating of pain change was used to assess change in pain
Measure: Global rating of change in pain Time: From baseline to 6-week post interventionaDescription: 10 point scale was used to assess intervention-specific satisfaction
Measure: Intervention specific satisfaction Time: From baseline to 6-week post interventiona