Covid 19 Research using Clinical Trials (Home Page)
Report for D007409: Intestinal Atresia NIH
(Synonyms: Intestinal Atresia)
Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation
Correlated Drug Terms (0)
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Correlated MeSH Terms (0)
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There is one clinical trial.
Clinical Trials
1 In-Utero Vascular Accidents in Neonates From COVID-19 Infected Mothers
The pregnancy related pro-thrombotic state, in addition to the COVID-19 associated hypercoagulability may have unknown consequences to the developing fetus. Hence, this proposal seeks to address this question that may have important implications for women that contract this virus during gestation.
NCT04431869 Pregnancy Related COVID Intestinal Atresia Limb Anomaly MeSH:Intestinal Atresia
HPO:Intestinal atresia Jejunal atresia
Primary Outcomes
Description: Evaluate rates of intestinal atresias and limb anomalies in neonates born to women that contract SARS-CoV-2 during pregnancy in the first 30 days of life
Measure: Rates of intestinal atresias and limb abnormalities Time: 12 months
Description: Rates of preterm labor, fetal growth restriction and spontaneous abortions for women that are known to be infected with SARS-CoV-2 during gestation
Measure: Rates of preterm labor, fetal growth restriction and spontaneous abortions Time: 12 months
Description: For neonates identified in the NICU with intestinal atresias and limb anomalies, we will test the mothers for the presence of SARS-CoV-2 antibodies that may represent an asymptomatic carrier during gestation
Measure: Rates of maternal SARS-CoV-2 infection among mothers to infants born with intestinal atresias or limb anomalies Time: 12 months
HPO Nodes
HP:0011100: Intestinal atresia
Genes 47
CEP57 MYCN PORCN PTCH1 SEMA3E CHD7 CEP57 RTTN ITGB4 CENPF ITGA6 FLI1 TTC7A SUFU SIN3A SIX3 GAS1 FGF8 NODAL DIS3L2 FOXF1 TCTN3 DLL1 BUB3 FOXH1 PIGN TRIP13 GLI2 RAD51C FBN2 RFX6 ERGIC1 DISP1 RERE TTC7A CDON SHH BUB1 TDGF1 CHRM3 BUB1B TGIF1 FGFR1 SPINK5 RFWD3 SALL1 ZIC2 Protein Mutations 0
SNP 0
Primary Outcomes
Description: Evaluate rates of intestinal atresias and limb anomalies in neonates born to women that contract SARS-CoV-2 during pregnancy in the first 30 days of life
Measure: Rates of intestinal atresias and limb abnormalities Time: 12 monthsDescription: Rates of preterm labor, fetal growth restriction and spontaneous abortions for women that are known to be infected with SARS-CoV-2 during gestation
Measure: Rates of preterm labor, fetal growth restriction and spontaneous abortions Time: 12 monthsDescription: For neonates identified in the NICU with intestinal atresias and limb anomalies, we will test the mothers for the presence of SARS-CoV-2 antibodies that may represent an asymptomatic carrier during gestation
Measure: Rates of maternal SARS-CoV-2 infection among mothers to infants born with intestinal atresias or limb anomalies Time: 12 months