Covid 19 Research using Clinical Trials (Home Page)
Report for D012877: Skin Manifestations NIH
(Synonyms: Skin Manife, Skin Manifestations)
Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation
Correlated Drug Terms (1)
| Name (Synonyms) | Correlation | |
|---|---|---|
| drug745 | Detection of anti-COVID-19 antibody level Wiki | 1.00 |
Correlated HPO Terms (0)
| Name (Synonyms) | Correlation |
|---|
There is one clinical trial.
Clinical Trials
1 Assessment of Skin Manifestations Occuring During Covid-19 Infection With a Special Focus on Chilbains
Some patients infected by covid-19 develop skin manifestations. These manifestations are still not well known and there pathophysiology remain unclear. Among them, acral manifestation resembling to chilblains appears frequent and quite specific. The aim of this project is to better characterize the cutaneous manifestations occurring during Covid-19 infection with a special focus on chilblains. These acral manifestation could be due to a direct viral effect, but also to microthrombosis or vascularitis. Understanding the pathomechanisms involved could provide interesting clue for understanding not only the skin manifestations but also some of the other systemic symptoms associated to covid-19 infection. This study plan to characterize these acral manifestations by analyzing the clinical and dermoscopic patterns and to correlate them with the non-invasive vascular explorations but also immune and coagulopathy explorations that are done in the CHU of Nice in covid-19 patients.
NCT04344119 Skin Manifestations COVID Chilblains MeSH:Skin Manifestations Chilblains
Primary Outcomes
Description: Type and description of the skin manifestations with a special focus on patients with chilblains
Measure: Clinical skin manifestations Time: 3 monthsSecondary Outcomes
Description: Data on Histology (HE staining and immunofluorescence) and on biology (blood cells counts, CRP and immune profile) will be collected in covid patient with skin manifestation
Measure: Histology and biological data Time: 3 monthsDescription: Vascular examination will be performed by Capillaroscopy, laser-doppler or lung TDM if clinically required
Measure: Non invasive vascular examination Time: 3 months