CovidResearchTrials by Shray Alag


CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)


Report for D000068376: Compassion Fatigue NIH

(Synonyms: Compassion Fatigue)

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (5)


Name (Synonyms) Correlation
drug1226 Health Enhancement Program Wiki 0.71
drug442 Blood plasma Wiki 0.71
drug1767 MinnRAP Peer Support Program Wiki 0.71
drug1406 Infant Mental Health-Home Visiting Wiki 0.71
drug2756 Sudarshan Kriya Yoga (SKY) Wiki 0.71

Correlated MeSH Terms (8)


Name (Synonyms) Correlation
D000067073 Psychological Trauma NIH 0.82
D015775 Fractures, Stress NIH 0.71
D000073397 Occupational Stress NIH 0.41
D013315 Stress, Psychological NIH 0.14
D040921 Stress Disorders, Traumatic NIH 0.14
D013313 Stress Disorders, Post-Traumatic NIH 0.13
D004194 Disease NIH 0.12
D001008 Anxiety Disorders NIH 0.11

Correlated HPO Terms (0)


Name (Synonyms) Correlation

There are 2 clinical trials

Clinical Trials


1 Breath Regulation and Yogic Exercise An Online Therapy for Calm and Happiness (BREATH): an RCT for Frontline Hospital and Long-term Care Home Staff Managing the COVID-19 Pandemic

This study will examine the feasibility of conducting an online Randomized Controlled Trial (RCT) in frontline hospital and long term care healthcare staff in managing COVID-19 patients in London, ON. The study will randomize participants to Sudarshan Kriya Yoga (SKY) or a Health Enhancement Program (HEP).

NCT04368676 Job St Job Stress Workplace Stress Compassion Fatigue Psychological Trauma Healthcare Workers Healthcare Providers Other: Sudarshan Kriya Yoga (SKY) Other: Health Enhancement Program
MeSH:Compassion Fatigue Occupational Stress Psychological Trauma

Primary Outcomes

Description: The number of participants recruited per month will be calculated as a feasibility measure.

Measure: Rate of participant recruitment

Time: 1 year

Description: The retention rate of participants will be calculated as a feasibility measure.

Measure: Rate of retention

Time: 1 year

Description: The completeness of study assessments will be assessed as a feasibility measure by calculating the missing percentage of data in case report forms.

Measure: Completeness of data entry

Time: 1 year

Description: The cost of both study interventions will be calculated to assess the total study cost for interventions and the cost per participant. This information will be used as a feasibility measure.

Measure: Cost of interventions

Time: 1 year

Description: The total of unexpected costs will be calculated as a feasibility measure.

Measure: Unexpected costs

Time: 1 year

Secondary Outcomes

Description: The Athens Insomnia Scale will be used to assess insomnia. This scale is an 8-item, self-rated measure of the extent of sleep difficulties over the last 30 days with each item representing a different aspect of sleep (e.g. "Overall Quality of Sleep"). Ratings are from 0 to 4, with 0 being no difficulty with the item and 4 being the most difficulty with the item. Higher overall scores on this scale indicate higher difficulties with sleep.

Measure: Change in Athens Insomnia Scale

Time: Change from Week 0 to week 3 and to week 5

Description: The Generalized Anxiety Disorder 7-item scale (each scored 0-3) is a self-rated measure of anxiety and has been validated for the diagnosis of Generalized Anxiety Disorder in the adult population. Scores range from 0 to 21. Higher scores indicate greater anxiety symptoms (5-9, mild anxiety; 10-14, moderate anxiety; 15-21 severe anxiety).

Measure: Change in Generalized Anxiety Disorder 7-item scale

Time: Change from Week 0 to week 3 and to week 5

Description: The Patient Health Questionnaire (PHQ-9) is a 9-item, self-rated measure of depression which has been validated for screening a major depressive episode in adults. Total scores indicate various levels of depression: 0-4, no depression; 5-9, mild depression; 10-14, moderate depression; 15-19, moderately severe depression; 20-27, severe depression.

Measure: Change in Patient Health Questionnaire 9

Time: Change from Week 0 to week 3 and to week 5

Description: The Connor-Davidson Resilience Scale (CD-RISC) is a brief self-rated assessment tool that comprises of 10 items, each rated on a 5-point Likert scale (0 = not true at all to 4 = true nearly all the time). Higher scores reflect greater resilience, which is a measure of one's ability to cope with stress. The scale demonstrated strong reliability and validity and has been studied in a variety of populations including medical personnel, nurses, social workers and physicians).

Measure: Change in Connor-Davidson Resilience Scale

Time: Change from Week 0 to week 3 and to week 5

2 The Professional Peer Resilience Initiative: Leveraging a Data-Driven Model to Maximize the Resilience of Healthcare Workers During the COVID-19 Pandemic

The Professional Peer Resilience Initiative (PPRI) study is an observational study aimed at understanding how symptoms of traumatic stress and resilience evolve over time in the University of Minnesota (UMN) healthcare workforce during the coronavirus disease 2019 (COVID-19) pandemic. The study is being conducted concurrently with a UMN peer support program called the MinnRAP program and will remotely administer quality of life and mental health surveys to healthcare workers before they start the MinnRAP program and throughout their participation in the program.

NCT04396600 Stress Stress Disorder Stress, Psychological Trauma, Psychological Anxiety Anxiety State Post Traumatic Stress Disorder Secondary Traumatic Stress Professional Quality of Life Stress Related Disorder Stress Reaction Stress Risk Mental Resilience Emotional Resilience Behavioral: MinnRAP Peer Support Program
MeSH:Disease Compassion Fatigue Fractures, Stress Anxiety Disorders Stress Disorders, Traumatic Stress Disorders, Post-Traumatic Stress, Psychological Psychological Trauma

Primary Outcomes

Description: Professional Quality of Life Questionnaire (proQOL): min score of 10; max score of 50; higher scores mean worse outcome

Measure: Change in professional quality of life

Time: Before peer support program, through study completion (an average of 7 months)

Secondary Outcomes

Description: Stress Risk & Resilience Self-Index: min score 0; max score of 12; higher scores mean worse outcome

Measure: Change in mental health symptoms and resilience markers

Time: Before peer support program, through study completion (an average of 7 months)


HPO Nodes