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Report for D061218: Depressive Disorder, Treatment-Resistant NIH

(Synonyms: Depressive Disorder, Tr, Depressive Disorder, Treat, Depressive Disorder, Treatment-R, Depressive Disorder, Treatment-Resistant)

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (3)


Name (Synonyms) Correlation
drug3133 Written Information Wiki 1.00
drug1573 Lifestyle change promotion program Wiki 1.00
drug1755 Mindfullness based cognitive program Wiki 1.00

Correlated MeSH Terms (1)


Name (Synonyms) Correlation
D003866 Depressive Disorder NIH 0.22

Correlated HPO Terms (1)


Name (Synonyms) Correlation
HP:0000716 Depressivity HPO 0.22

There is one clinical trial.

Clinical Trials


1 Effectiveness of a Healthy Lifestyle Promotion Program as Adjunctive Teletherapy for Treatment-resistant Major Depression During Covid 19 Pandemic: A Randomized Clinical Trial Protocol

The main objective of the study will be to evaluate the effectiveness of an adjuvant lifestyle-based intervention for treatment-resistant patients with major depressive disorder. Patients will be allocated to one of these three groups: 1)Treatment prescribed by their mental health team plus written lifestyle change suggestions 2)Treatment prescribed by their mental health team plus written lifestyle change suggestions plus 8-week Mindfulness-based cognitive therapy (MBCT) program 3) Treatment prescribed by their mental health team plus written lifestyle change suggestions plus 8-week lifestyle change promotion program. We will collect patient data using the questionnaires administered at baseline, immediately after the intervention, and at six and 12-month follow-up. The primary outcome will be depression severity and secondary outcomes will include health-related quality of life.

NCT04428099 Depressive Disorder, Treatment-Resistant Behavioral: Lifestyle change promotion program Behavioral: Mindfullness based cognitive program Behavioral: Written Information
MeSH:Depressive Disorder Depressive Disorder, Treatment-Resistant
HPO:Depressivity

Primary Outcomes

Description: Beck Depression Inventory-II (BDI-II)

Measure: Depression severity

Time: 12 month

Secondary Outcomes

Description: Questionnaire (EQ-5D)

Measure: Health-related quality of life

Time: 12 month


HPO Nodes