CovidResearchTrials by Shray Alag


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Report for D001248: Asthenopia NIH

(Synonyms: Asthenopia)

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (3)


Name (Synonyms) Correlation
drug896 Digital intervention Wiki 1.00
drug1413 Information-only intervention Wiki 1.00
drug416 Biological/Vaccine: Angiotensin peptide (1-7) derived plasma Wiki 1.00

Correlated MeSH Terms (2)


Name (Synonyms) Correlation
D013180 Sprains and Strains NIH 0.71
D001008 Anxiety Disorders NIH 0.15

Correlated HPO Terms (0)


Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials


1 Reducing Eye Strain and Anxiety Using a Digital Intervention During Online Learning Class Recess Among Children at Home: A Randomized Controlled Trial

The primary aim of the current study is to conduct a cluster-randomized control trial to evaluate the effectiveness of a novel digital intervention in reducing anxiety and digital eye strain compared to usual care among Chinese children during the period of home confinement.

NCT04309097 Anxiety Digital Eye Strain Behavioral: Digital intervention Behavioral: Information-only intervention
MeSH:Asthenopia Sprains and Strains Anxiety Disorders

Primary Outcomes

Description: Change in anxiety will be measured by the Spence Children's Anxiety Scale (SCAS) designed by Spence (1998). The SCAS (45-item) is self-report scale with a 4-point Likert type, consisting of 44 items and one open-ended question. Overall assessment is done by total score.

Measure: Change in anxiety

Time: Baseline & at 2 weeks

Secondary Outcomes

Description: Syndromes of digital eye strain will be measured with the Computer Vision Syndrome Questionnaire (CVS‐Q) designed by Seguí et al (2015). The self-reported CVS-Q questionnaire (16-item) evaluates the frequency (never, occasionally or often/always) and the intensity (moderate or intense) of 16 symptoms: burning, itching, feeling of a foreign body, tearing, excessive blinking, eye redness, eye pain, heavy eyelids, dryness, blurred vision, double vision, difficulty focusing for near vision, increased sensitivity to light, colored halos around objects, feeling that sight is worsening, and headache. Overall assessment is done by total score.

Measure: Change in syndromes of digital eye strain

Time: Baseline & at 2 weeks

Description: The PROMIS pediatric sleep disturbance questionnaire (4-item), designed by Forrest et al (2018), assesses self-reported experiences of sleep disturbance over the past 7 days. Raw score will be converted to T-Score.

Measure: Change in sleeping quality

Time: Baseline & at 2 weeks

Description: Participants will be asked to indicate the average time in hours per day spent on each the following activities: reading, writing, computer/PAD use, smart phone, watching TV, and playing video games.

Measure: Changes in time (hour) spent on different near work activities

Time: Baseline & at 2 weeks


HPO Nodes