CovidResearchTrials by Shray Alag


CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)


Report for D000073296: Noncommunicable Diseases NIH

(Synonyms: Noncommunicable Diseases)

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (3)


Name (Synonyms) Correlation
drug877 DiaNose Wiki 0.71
drug3377 non-interventional Wiki 0.71
drug812 DAS181 Wiki 0.29

Correlated MeSH Terms (8)


Name (Synonyms) Correlation
D003327 Coronary Disease NIH 0.29
D050177 Overweight NIH 0.27
D006331 Heart Diseases NIH 0.25
D002908 Chronic Disease NIH 0.20
D007249 Inflammation NIH 0.14
D002318 Cardiovascular Diseases NIH 0.13
D003141 Communicable Diseases NIH 0.06
D007239 Infection NIH 0.04

Correlated HPO Terms (1)


Name (Synonyms) Correlation
HP:0001626 Abnormality of the cardiovascular system HPO 0.13

There are 2 clinical trials

Clinical Trials


1 Nutritional Habits, Does it Affect Coronavirus Disease 2019 (COVID-19) Infection Outcome? An Egyptian Experience

As of May 30th more than 23,000 cases of COVID -19 cases were confirmed in Egypt with total deaths of 913. Post viral entry, intense immune response against the virus with infiltration of monocytes and macrophages into alveolar cells with decreasing number of lymphocytes in peripheral blood along with reduced lymphocytes in lymphoid organs, hypercoagulability, thrombosis and multiple organ damage, The gut microbiota and immune homeostasis seem to have a back and forth relationship. Also, gut microbiota derived signals are known to tune the immune cells for pro and anti-inflammatory responses thereby affecting the susceptibility to various diseases. Healthy gut microbiome essentially could be pivotal in maintaining an optimal immune system to prevent an array of excessive immune reactions that eventually become detrimental to lungs and vital organ systems. Numerous studies have shown that the patient's nutritional status have a significant effect on an individual's immunity and over all health status and it has been suggested that nutritional deficiencies may predispose to severe forms of COVID-19 infections. Co-existing non-communicable chronic diseases (NCDs) in COVID-19 patients have been found to delay patients recovery and worsen their prognosis, the reason may be due to aggravated inflammatory pathology found in NCDs exacerbating COVID-19 infection. The aim of the study is to evaluate the role dietary habits among COVID-19 Egyptian patients and whether type of diet (Mediterranean or Western) will affect disease outcomes

NCT04447144 Covid19 Chronic Inflammation Non-Communicable Chronic Diseases
MeSH:Inflammation Chronic Disease Noncommunicable Diseases

Primary Outcomes

Description: To assess the relation between type of diet in mild to moderate COVID 19, to the fate of their course; either improvement or progression

Measure: Western versus Mediterranean diet in COVID-19 outcome

Time: 2 months

Description: To asses any possible links between gut microbiome and the lung affecting clinical presentation of mild to moderate COVID cases; as diarrhea, loss of taste or smell

Measure: Gut- Lung axis in COVID-19

Time: 2 months

Description: Possible protective effects of minerals and vitamins against COVID-19 respiratory illness

Measure: Protective role of minerals and vitamins in COVID-19 patients

Time: 2 months

Description: Trying to explain the link between non-communicable disease severity and COVID-19 prognosis

Measure: non-communicable diseases and COVID-19

Time: 2 months

2 Analysis of Chronic Non-infectious Diseases Dynamics After COVID-19 Infection in Adult Patients

Non-commercial depersonalized multi-centered registry study on analysis of chronic non-infectious diseases dynamics after SARS-CoV-2 infection in adults.

NCT04492384 Covid19 SARS-CoV-2 Infection Pneumonia Copd CKD Cardiac Event Overweight and Obesity Cardiovascular Diseases Diabetes Hypertension Coronary Heart Disease Other: non-interventional
MeSH:Infection Communicable Diseases Heart Diseases Coronary Disease Overweight Noncommunicable Diseases Cardiovascular Diseases
HPO:Abnormality of the cardiovascular system

Primary Outcomes

Description: percentage of patients with non-infectious diseases relating to overall number of patients registered in study

Measure: rate of non-infectious diseases

Time: 12 month since a moment of request of medical help

Description: correlation between number of patients with COVID-19 of various severity and number of pre-existing conditions and their severity among these groups

Measure: severity of COVID-19 depending on pre-existing diseases

Time: 12 month since a moment of request of medical help

Description: Registration of disability or change of disability status

Measure: disability registration / change of disability status

Time: 12 month since a moment of request of medical help

Description: rate of deaths among registered participants

Measure: rate of letal outcomes

Time: 12 month since a moment of request of medical help

Description: correlation between number of deaths and pre-existing diseases

Measure: rate of letal outcomes depending on pre-existing disease

Time: 12 month since a moment of request of medical help


HPO Nodes