CovidResearchTrials by Shray Alag

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Report for D000073436: Microvascular Rarefaction NIH

(Synonyms: Microvascular Rarefaction)

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (2)

Name (Synonyms) Correlation
drug2607 Serology test follow-up Wiki 1.00
drug3262 evaluation of skin microvascular flow and reactivity Wiki 1.00

Correlated MeSH Terms (2)

Name (Synonyms) Correlation
D045169 Severe Acute Respiratory Syndrome NIH 0.05
D018352 Coronavirus Infections NIH 0.04

Correlated HPO Terms (0)

Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials

1 Investigation of Systemic Microvascular Flow and Reactivity in Patients Presenting in the Acute Phase of Coronavirus Disease-19.

Considering that the intensity of systemic microvascular changes in patients in the acute phase of COVID-19 could be related to disease progression and prognosis, the present cross-sectional and observational study aims to investigate the presence of endothelial dysfunction in these patients, also looking for to evaluate associations between the presence of endothelial dysfunction and demographic, clinical and laboratory variables.

NCT04406545 Coronavirus Infection Endothelial Dysfunction Microvascular Rarefaction Other: evaluation of skin microvascular flow and reactivity
MeSH:Coronavirus Infections Severe Acute Respiratory Syndrome Microvascular Rarefaction

Primary Outcomes

Description: skin laser Doppler perfusion monitoring before and after local thermal hyperemia

Measure: To evaluate, through laser doppler, the presence of changes in systemic microvascular endothelial function in patients in the acute phase of COVID-19.

Time: Microvascular reactivity will be evaluated after a 20-minute rest in the supine position in a temperature-controlled room.

HPO Nodes