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Report for D061219: Olfactory Nerve Injuries NIH

(Synonyms: Olfactory Nerve Injuries)

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (1)


Name (Synonyms) Correlation
drug1428 Injection into olfactory cleft Wiki 1.00

Correlated MeSH Terms (3)


Name (Synonyms) Correlation
D009422 Nervous System Diseases NIH 0.58
D000857 Olfaction Disorders NIH 0.27
D004194 Disease NIH 0.17

Correlated HPO Terms (1)


Name (Synonyms) Correlation
HP:0000458 Anosmia HPO 0.27

There is one clinical trial.

Clinical Trials


1 Intranasal Injection of Platelet-rich Plasma Versus Saline for Treatment of Olfactory Dysfunction

This randomized clinical trial will evaluate the benefit of platelet-rich plasma (PrP) in the treatment of olfactory dysfunction. PrP can be isolated from a patient's own blood and has been found in previous studies to have anti-inflammatory and pro-regenerative properties. It has been used across multiple specialties, such as Orthopedics, Facial Plastics, Dermatology, Neurology in injected form to treat a wide variety of tissues to encourage the body's inherent regenerative capacity. We have completed a pilot study here evaluating it's use in olfactory loss which demonstrated safety and also suggested efficacy. Therefore, we aim to assess the ability of PrP to improve olfactory function in patients with decreased sense of smell.

NCT04406584 Olfactory Disorder Olfaction Disorders Olfactory Nerve Injuries Olfactory Nerve Disorder Olfactory Nerve Diseases Procedure: Injection into olfactory cleft
MeSH:Olfaction Disorders Olfactory Nerve Injuries Olfactory Nerve Diseases Disease Nervous System Diseases
HPO:Anosmia

Primary Outcomes

Description: Using Sniffin' Sticks olfactory testing pens to test smell

Measure: Smelling ability

Time: 6 months


HPO Nodes