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  • HP:0001004: Lymphedema
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    HP:0001004: Lymphedema

    Developed by Shray Alag, The Harker School
    Sections: Correlations, Clinical Trials, and HPO

    Correlations computed by analyzing all clinical trials.

    Navigate: Clinical Trials and HPO


    Correlated Drug Terms (2)


    Name (Synonyms) Correlation
    drug1329 Flexitouch Plus with Cellular Connectivity (FT-CC) Wiki 1.00
    drug784 Chloroquine phosphate Wiki 0.58

    Correlated MeSH Terms (3)


    Name (Synonyms) Correlation
    D000072656 Breast Cancer Lymphedema NIH 1.00
    D008209 Lymphedema NIH 1.00
    D001943 Breast Neoplasms NIH 0.45

    Correlated HPO Terms (1)


    Name (Synonyms) Correlation
    HP:0003002 Breast carcinoma HPO 0.45

    Clinical Trials

    Navigate: Correlations   HPO

    There is one clinical trial.


    1 A Feasibility Study Evaluating the Impact Flexitouch Plus With Connectivity Has on Compliance in Patients With Breast Cancer-Related Lymphedema (BCRL)

    The objective of this study is to demonstrate the feasibility of using the Flexitouch Plus with Cellular Connectivity (FT-CC) to monitor device use data to determine if reminders to patients impact compliance, and to identify the impact device compliance has on arm girth, quality of life (QOL), and symptom assessment.

    NCT04432727
    Conditions
    1. Breast Cancer Lymphedema
    Interventions
    1. Device: Flexitouch Plus with Cellular Connectivity (FT-CC)
    MeSH:Breast Neoplasms Lymphedema Breast Cancer Lymphedema
    HPO:Breast carcinoma Lymphedema Neoplasm of the breast

    Primary Outcomes

    Description: Compare the rate of compliance (defined as the number of days device used/total study days) in patients treated with PASSIVE FT-CC and ACTIVE FT-CC.

    Measure: Compliance

    Time: Changes between 30 days after device training and 60 days after device training

    Secondary Outcomes

    Description: Comparison of partially compliant and compliant arm girth in patients treated with FT-CC. Arm girth is measured in cm.

    Measure: Change in Arm Girth

    Time: Changes between baseline, 30 days after device training, and 60 days after device training

    Description: Comparison of partially compliant and compliant quality of life in patients treated with FT-CC via Lymphedema Quality of Life Tool (LYMQOL ARM). Lymphedema Quality of Life Tool (LYMQOL-ARM) includes sub-scores for Function (range 10-40), Appearance (range 5-20), Symptoms (range 6-24), and Emotion (range 6-24) where lower scores represent a better outcome. It also includes an Overall QOL sub-score (range 0-10) where a higher score represents a better outcome.

    Measure: Quality of Life Assessment via LYMQOL ARM

    Time: Changes between baseline, 30 days after device training, and 60 days after device training

    Description: Comparison of partially compliant and compliant quality of life in patients treated with FT-CC by via The RAND 36-Item Short Form Survey (SF-36). The RAND 36-Item Short Form Survey (SF-36) taps eight health concepts: physical functioning, bodily pain, role limitations due to physical health problems, role limitations due to personal or emotional problems, emotional well-being, social functioning, energy/fatigue, and general health perceptions. It also includes a single item for perceived change in health. Min value: 0, Max value: 100. Higher scores represent a better outcome.

    Measure: Quality of Life Assessment via SF-36

    Time: Changes between baseline, 30 days after device training, and 60 days after device training

    Description: Comparison of partially compliant and compliant symptoms in patients treated with FT-CC by via The Lymphedema Symptom Intensity and Distress Survey-ARM (LSIDS-A). The Lymphedema Symptom Intensity and Distress Survey is a questionnaire used to assess intensity and distress of symptoms in patients with lymphedema of the arm. This includes sub-scores for soft tissue sensation (range 0-10), neurological sensation (0-10), function, (0-10), biobehavioral (0-10), resource (0-10), sexuality (0-10), activity (0-10). Higher score represents worse outcome.

    Measure: Symptoms Assessment via LSIDS-A

    Time: Changes between baseline, 30 days after device training, and 60 days after device training

    HPO Nodes


    Reports

    Data processed on September 26, 2020.

    An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.

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