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    HP:0002355: Difficulty walking

    Developed by Shray Alag, The Harker School
    Sections: Correlations, Clinical Trials, and HPO

    Correlations computed by analyzing all clinical trials.

    Navigate: Clinical Trials and HPO


    Correlated Drug Terms (1)


    Name (Synonyms) Correlation
    drug1846 Live Long Walk Strong rehabilitation program Wiki 1.00

    Correlated MeSH Terms (1)


    Name (Synonyms) Correlation
    D051346 Mobility Limitation NIH 0.71

    Correlated HPO Terms (0)


    Name (Synonyms) Correlation

    Clinical Trials

    Navigate: Correlations   HPO

    There is one clinical trial.


    1 The Live Long Walk Strong Rehabilitation Program: What Features Improve Mobility Skills?

    This study is being performed to evaluate the efficacy of the Live Long Walk Strong rehabilitation program in Veterans 50 years and older. This study will also examine the features of the program that contribute to improved gait speed.

    NCT04026503
    Conditions
    1. Mobility Limitation
    Interventions
    1. Other: Live Long Walk Strong rehabilitation program
    MeSH:Mobility Limitation
    HPO:Difficulty walking

    Primary Outcomes

    Description: Gait speed change will be assessed within 2 weeks post intervention and then in 8 and 16 weeks of subsequent follow-up.

    Measure: Gait Speed

    Time: within 2 weeks, 8 weeks, 16 weeks

    HPO Nodes


    HP:0002355: Difficulty walking
    Genes 271
    CCN6 GMPPB ERLIN1 DNM1 GLE1 CAPN3 SH3TC2 VAMP1 NEB SCN3A NKX6-2 FKRP PSAP ERLIN1 SLC13A5 STRADA SURF1 PLEKHG5 DHTKD1 DMD TIA1 ACTL6B ALG2 KLHL9 TRAPPC11 DNM2 NUBPL CNKSR2 REEP1 SACS SLC1A2 HERC1 COASY ATP6V1A WASHC5 MED25 MYOT LRP4 SCN8A B4GALNT1 CYP2R1 MSTO1 SYNJ1 PIK3CA WWOX MYF6 TPM2 TRAK1 HSPB3 KLHL41 GALC INTS1 AP4M1 SLC5A7 TGM6 GRID2 NTRK2 WARS1 SAMHD1 ALG14 NACC1 DAG1 MORC2 AKT1 RSPRY1 GAN CYP27B1 SGCD GABRA2 ATRX HK1 CIZ1 SGCB ELOVL5 HK1 TCAP COL13A1 MARCHF6 TRNW NEB CACNA1B GYG1 PEX6 TREX1 TTN DES CAPN3 DYSF TPM2 LRP12 MORC2 CRPPA DDHD1 ATP13A2 TTBK2 SPG21 PNPLA2 TRAPPC11 BIN1 FA2H ACTA1 WDR48 ORAI1 PDGFB ARSA SETX SLC18A3 CYFIP2 MICU1 FLNC ABHD5 CAPN1 PUS3 GJB1 BICD2 TRAPPC11 RNASEH2B TRAF7 GOSR2 SUFU MICU1 AP3B2 EEF1A2 KCNB1 TAF1 TIA1 FKRP STXBP1 ALG14 NF2 NUS1 GPAA1 CPT1C TBC1D23 CACNA1A HACE1 MSTO1 PDK3 DARS2 MYO9A RARS1 BAP1 GPT2 CRYAB MATR3 DNM1 AGRN GABRG2 TERT GRIN2D SMO TPP1 ACTA1 SNAP25 CDK8 VCP GABRB2 DPAGT1 CLTC CHCHD10 BAP1 BVES ATP7B KBTBD13 ATP13A2 TPM3 PGAP1 NDUFS8 SLC25A19 TK2 NECAP1 SLC30A10 PRX SZT2 KLC2 VCP MYH7 AP4S1 C19ORF12 AARS1 GJC2 SLC52A2 UBA5 MYPN VDR NOP56 ARV1 ASAH1 KY AP4B1 ERLIN2 TGM6 CDKL5 ADAR IFIH1 YWHAG SMARCB1 MFN2 IBA57 VAMP1 RAB11B SLC25A1 PARS2 ARSI RYR1 HSPB1 HPCA CYP27B1 MECP2 KCNA2 ATP6 MTMR14 PPP3CA FKRP AP4E1 GABRB2 FKTN ARL6IP1 SPART POMT1 CHAT FLRT1 POMT1 KCNC3 RNASEH2C SLC18A3 FA2H NKX2-1 SBF2 SQSTM1 FHL1 GBA2 STUB1 FGF12 RNU12 RNASEH2A DHDDS DNA2 ADCY5 USP9X KCND3 GABRA5 POMT2 SLC5A7 C12ORF65 ARL6IP1 EIF2S3 SMARCE1 C12ORF65 TTN GFPT1 CYP2R1 PYCR2 PMP2 KCNA2 HCN1 SYT2 TPM3 PNPLA2 RTN2 CPT1C KLHL41 FBXO38 POMT1 SYNGAP1 SLC30A9 SLC34A3 FGF14 ANO5 SNAP25 FDX2
    Protein Mutations 0
    SNP 0

    HPO

    Alphabetical listing of all HPO terms. Navigate: Correlations   Clinical Trials


    HPO Nodes


    HP:0002355: Difficulty walking
    Genes 271
    CCN6 GMPPB ERLIN1 DNM1 GLE1 CAPN3 SH3TC2 VAMP1 NEB SCN3A NKX6-2 FKRP PSAP ERLIN1 SLC13A5 STRADA SURF1 PLEKHG5 DHTKD1 DMD TIA1 ACTL6B ALG2 KLHL9 TRAPPC11 DNM2 NUBPL CNKSR2 REEP1 SACS SLC1A2 HERC1 COASY ATP6V1A WASHC5 MED25 MYOT LRP4 SCN8A B4GALNT1 CYP2R1 MSTO1 SYNJ1 PIK3CA WWOX MYF6 TPM2 TRAK1 HSPB3 KLHL41 GALC INTS1 AP4M1 SLC5A7 TGM6 GRID2 NTRK2 WARS1 SAMHD1 ALG14 NACC1 DAG1 MORC2 AKT1 RSPRY1 GAN CYP27B1 SGCD GABRA2 ATRX HK1 CIZ1 SGCB ELOVL5 HK1 TCAP COL13A1 MARCHF6 TRNW NEB CACNA1B GYG1 PEX6 TREX1 TTN DES CAPN3 DYSF TPM2 LRP12 MORC2 CRPPA DDHD1 ATP13A2 TTBK2 SPG21 PNPLA2 TRAPPC11 BIN1 FA2H ACTA1 WDR48 ORAI1 PDGFB ARSA SETX SLC18A3 CYFIP2 MICU1 FLNC ABHD5 CAPN1 PUS3 GJB1 BICD2 TRAPPC11 RNASEH2B TRAF7 GOSR2 SUFU MICU1 AP3B2 EEF1A2 KCNB1 TAF1 TIA1 FKRP STXBP1 ALG14 NF2 NUS1 GPAA1 CPT1C TBC1D23 CACNA1A HACE1 MSTO1 PDK3 DARS2 MYO9A RARS1 BAP1 GPT2 CRYAB MATR3 DNM1 AGRN GABRG2 TERT GRIN2D SMO TPP1 ACTA1 SNAP25 CDK8 VCP GABRB2 DPAGT1 CLTC CHCHD10 BAP1 BVES ATP7B KBTBD13 ATP13A2 TPM3 PGAP1 NDUFS8 SLC25A19 TK2 NECAP1 SLC30A10 PRX SZT2 KLC2 VCP MYH7 AP4S1 C19ORF12 AARS1 GJC2 SLC52A2 UBA5 MYPN VDR NOP56 ARV1 ASAH1 KY AP4B1 ERLIN2 TGM6 CDKL5 ADAR IFIH1 YWHAG SMARCB1 MFN2 IBA57 VAMP1 RAB11B SLC25A1 PARS2 ARSI RYR1 HSPB1 HPCA CYP27B1 MECP2 KCNA2 ATP6 MTMR14 PPP3CA FKRP AP4E1 GABRB2 FKTN ARL6IP1 SPART POMT1 CHAT FLRT1 POMT1 KCNC3 RNASEH2C SLC18A3 FA2H NKX2-1 SBF2 SQSTM1 FHL1 GBA2 STUB1 FGF12 RNU12 RNASEH2A DHDDS DNA2 ADCY5 USP9X KCND3 GABRA5 POMT2 SLC5A7 C12ORF65 ARL6IP1 EIF2S3 SMARCE1 C12ORF65 TTN GFPT1 CYP2R1 PYCR2 PMP2 KCNA2 HCN1 SYT2 TPM3 PNPLA2 RTN2 CPT1C KLHL41 FBXO38 POMT1 SYNGAP1 SLC30A9 SLC34A3 FGF14 ANO5 SNAP25 FDX2
    Protein Mutations 0
    SNP 0

    Reports

    Data processed on September 26, 2020.

    An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.

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    4,180 reports on interventions/drugs

    MeSH

    691 reports on MeSH terms

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    263 reports on HPO terms

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