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  • HP:0008711: Benign prostatic hyperplasia
  • Pneumonia (359) Respiratory tract infection (38) Neoplasm (36) Abnormality of the cardiovascular system (34) Diabetes mellitus (33) Depressivity (29) Acute kidney injury (27) Hypoxemia (26) Hypertension (24) Abnormal lung morphology (24) Thromboembolism (22) Anosmia (20) Myocardial infarction (20) Arthritis (19) Type II diabetes mellitus (18) Stroke (16) Pulmonary embolism (16) Mental deterioration (15) Abnormality of coagulation (15) Pulmonary fibrosis (15) Chronic pulmonary obstruction (15) Abnormality of the kidney (14) Autistic behavior (14) Rheumatoid arthritis (14) Leukemia (14) Interstitial pneumonitis (14) Pulmonary obstruction (14) Asthma (13) Chronic pain (13) Congestive heart failure (12) Deep venous thrombosis (12) Neoplasm of the lung (12) Autism (11) Obesity (11) Respiratory distress (11) Colitis (11) Ulcerative colitis (11) Crohn's disease (11) Type I diabetes mellitus (10) Abnormality of the liver (9) Coronary artery atherosclerosis (9) Inflammation of the large 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Jaundice (2) Lymphedema (2) Spasticity (2) Meningitis (2) Abnormal joint morphology (2) Hepatic steatosis (2) Hepatic failure (2) Tachycardia (2) Angina pectoris (2) Pancreatitis (2) Abnormality of blood and blood-forming tissues (2) Thrombocytopenia (2) Autoimmune thrombocytopenia (2) Gout (2) Diarrhea (2) Gastroesophageal reflux (2) Apnea (2) Neurodegeneration (2) Alopecia of scalp (2) Mutism (2) Transient ischemic attack (2) Hyperkinetic movements (2) Polyphagia (2) Hypotension (2) Atherosclerosis (2) Hypoventilation (2) Squamous cell carcinoma (2) Myelodysplasia (2) Back pain (2) Low back pain (2) Muscular dystrophy (2) Stillbirth (2) Acute myeloid leukemia (2) Lymphoproliferative disorder (2) Myeloproliferative disorder (2) Multiple myeloma (2) Intervertebral disc degeneration (2) Stridor (2) Postprandial hyperglycemia (2) Hemeralopia (2) Arteritis (2) Hepatitis (2) Glioblastoma multiforme (2) Cervix cancer (2) Small cell lung carcinoma (2) Endocarditis (2) Toxemia of pregnancy 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    HP:0008711: Benign prostatic hyperplasia

    Developed by Shray Alag, The Harker School
    Sections: Correlations, Clinical Trials, and HPO

    Correlations computed by analyzing all clinical trials.

    Navigate: Clinical Trials and HPO


    Correlated Drug Terms (9)


    Name (Synonyms) Correlation
    drug467 BI 730357 Wiki 1.00
    drug2107 Lasix® Wiki 1.00
    drug795 CRESTOR® Wiki 1.00
    Name (Synonyms) Correlation
    drug3130 Proxalutamide Wiki 1.00
    drug2116 Lenoxin® Wiki 1.00
    drug1288 Dutasteride Wiki 1.00
    drug2356 MetfoLiquid GeriaSan® Wiki 1.00
    drug2029 Ivermectin Wiki 0.21
    drug421 Azithromycin Wiki 0.16

    Correlated MeSH Terms (5)


    Name (Synonyms) Correlation
    D011470 Prostatic Hyperplasia NIH 1.00
    D006965 Hyperplasia NIH 1.00
    D000505 Alopecia NIH 0.71
    Name (Synonyms) Correlation
    D045169 Severe Acute Respiratory Syndrome NIH 0.04
    D018352 Coronavirus Infections NIH 0.04

    Correlated HPO Terms (1)


    Name (Synonyms) Correlation
    HP:0002293 Alopecia of scalp HPO 0.71

    Clinical Trials

    Navigate: Correlations   HPO

    There is one clinical trial.


    1 Anti-Androgen Treatment for COVID-19

    This study is intended to explore the possible protective role of anti-androgens in SARS-CoV-2 infection

    NCT04446429
    Conditions
    1. COVID-19
    2. SARS-CoV2
    3. Androgenetic Alopecia
    4. Prostate Cancer
    5. Benign Prostatic Hyperplasia
    6. SARS (Severe Acute Respiratory Syndrome)
    Interventions
    1. Drug: Dutasteride
    2. Drug: Ivermectin
    3. Drug: Azithromycin
    4. Drug: Proxalutamide
    MeSH:Severe Acute Respiratory Syndrome Coronavirus Infections Prostatic Hyperplasia Alopecia Hyperplasia
    HPO:Alopecia Alopecia of scalp Benign prostatic hyperplasia Frontal balding

    Primary Outcomes

    Description: Percentage of subjects hospitalized due to COVID-19

    Measure: COVID-19 hospitalization

    Time: 30 days

    Description: COVID Ordinal Scale defined as: Death Hospitalized on invasive mechanical ventilation or ECMO ( extracorporeal membrane oxygenation) Hospitalized on non-invasive ventilation or high flow nasal cannula Hospitalized on supplemental oxygen Hospitalized not on supplemental oxygen Not hospitalized with limitation in activity (continued symptoms) Not hospitalized without limitation in activity (no symptoms)

    Measure: COVID-19 Ordinal Outcomes Scale

    Time: 30 days

    Secondary Outcomes

    Description: Symptoms severity of COVID-19 using Brescia-COVID Respiratory Severity Scale (BCRSS)/Algorithm

    Measure: Symptoms severity of COVID-19

    Time: 30 days

    HPO Nodes


    HPO

    Alphabetical listing of all HPO terms. Navigate: Correlations   Clinical Trials


    HPO Nodes


    Reports

    Data processed on September 26, 2020.

    An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.

    Drug Reports   MeSH Reports   HPO Reports  

    Interventions

    4,180 reports on interventions/drugs

    MeSH

    691 reports on MeSH terms

    HPO

    263 reports on HPO terms

    All Terms

    Alphabetical index of all Terms

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    Python example via Google Colab Notebook