Developed by Shray Alag, The Harker School
Sections: Correlations,
Clinical Trials, and HPO
Navigate: Clinical Trials and HPO
Name (Synonyms) | Correlation | |
---|---|---|
drug1029 | Dexmedetomidine Injectable Product Wiki | 0.71 |
drug202 | Alteplase 50 MG [Activase] Wiki | 0.50 |
drug685 | Camostat Wiki | 0.32 |
Name (Synonyms) | Correlation | |
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D000071257 | Emergence Delirium NIH | 0.71 |
D003693 | Delirium NIH | 0.32 |
D013577 | Syndrome NIH | 0.14 |
Name (Synonyms) | Correlation |
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Navigate: Correlations HPO
There are 2 clinical trials
The overall objective of this study is to efficiently evaluate the clinical efficacy and safety of different investigational therapeutics among adults who have COVID-19 but are not yet sick enough to require hospitalization. The overall hypothesis is that through an adaptive trial design, potential effective therapies (single and combination) may be identified for this group of patients. COVID-19 Outpatient Pragmatic Platform Study (COPPS) is a pragmatic platform protocol designed to evaluate COVID-19 treatments by assessing their ability to reduce viral shedding (Viral Domain) or improve clinical outcomes (Clinical Domain). To be included into the platform, every investigational product will collect data for both Domain primary endpoints. Individual treatments to be evaluated in the platform will be described in separate sub-protocols.
Description: Defined as the time in days from randomization to the first of two consecutive negative RT-PCR results of self-collected nasal swabs
Measure: For Viral Domain:Time until cessation of shedding of SARS-CoV-2 virus Time: 28 daysDescription: Resolution is defined as the first study day where no symptoms are self-reported for 48 hours, not including sense of taste or smell, and defining recovery for fatigue and cough as mild or none. Participants who never experienced resolution will be censored at their last survey completion day.
Measure: For Clinical Domain: Time from randomization to sustained symptom resolution assessed over a 28-day period Time: 28 daysDescription: Defined as the first study day where no symptoms are self-reported, not including sense of taste or smell, and defining recovery for fatigue and cough as mild or none.
Measure: Time to first resolution Time: 28 daysThe overall objective of this study is to efficiently evaluate the clinical efficacy and safety of different investigational therapeutics among adults who have COVID-19 but are not yet sick enough to require hospitalization. The overall hypothesis is that through an adaptive trial design, potential effective therapies (single and combination) may be identified for this group of patients. COVID-19 Outpatient Pragmatic Platform Study (COPPS) is a pragmatic platform protocol designed to evaluate COVID-19 treatments by assessing their ability to reduce viral shedding (Viral Domain) or improve clinical outcomes (Clinical Domain). To be included into the platform, every investigational product will collect data for both Domain primary endpoints. Individual treatments to be evaluated in the platform will be described in separate sub-protocols.
Description: Defined as the time in days from randomization to the first of two consecutive negative RT-PCR results of self-collected nasal swabs
Measure: For Viral Domain:Time until cessation of shedding of SARS-CoV-2 virus Time: 28 daysDescription: Resolution is defined as the first study day where no symptoms are self-reported for 48 hours, not including sense of taste or smell, and defining recovery for fatigue and cough as mild or none. Participants who never experienced resolution will be censored at their last survey completion day.
Measure: For Clinical Domain: Time from randomization to sustained symptom resolution assessed over a 28-day period Time: 28 daysDescription: Defined as the first study day where no symptoms are self-reported, not including sense of taste or smell, and defining recovery for fatigue and cough as mild or none.
Measure: Time to first resolution Time: 28 daysAlphabetical listing of all HPO terms. Navigate: Correlations Clinical Trials
Data processed on January 01, 2021.
An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.
Drug Reports MeSH Reports HPO Reports