Developed by Shray Alag, The Harker School
Sections: Correlations,
Clinical Trials, and HPO
Navigate: Clinical Trials and HPO
Name (Synonyms) | Correlation | |
---|---|---|
drug1216 | Estradiol patch Wiki | 0.45 |
drug2873 | Rintatolimod Wiki | 0.45 |
drug2804 | Recombinant Interferon Alfa-2b Wiki | 0.45 |
Name (Synonyms) | Correlation | |
---|---|---|
drug2999 | Saliva sample Wiki | 0.45 |
drug2728 | Querying the INSEE database Wiki | 0.45 |
drug3071 | Serology SARS-CoV2 Wiki | 0.45 |
drug2182 | Niclosamide suspension Wiki | 0.45 |
drug30 | 1: Prone positioning Wiki | 0.45 |
drug383 | BNT162a1 Wiki | 0.45 |
drug387 | BNT162c2 Wiki | 0.45 |
drug42 | 2: No instruction regarding positioning Wiki | 0.45 |
drug384 | BNT162b1 Wiki | 0.26 |
drug385 | BNT162b2 Wiki | 0.22 |
drug2152 | Nasopharyngeal swab Wiki | 0.17 |
drug2490 | Placebo Wiki | 0.02 |
Name (Synonyms) | Correlation | |
---|---|---|
D054058 | Acute Coronary Syndrome NIH | 0.22 |
D012327 | RNA Virus Infections NIH | 0.16 |
D003141 | Communicable Diseases NIH | 0.10 |
Name (Synonyms) | Correlation | |
---|---|---|
HP:0002664 | Neoplasm HPO | 0.08 |
HP:0011947 | Respiratory tract infection HPO | 0.07 |
Navigate: Correlations HPO
There are 5 clinical trials
This registry will evaluate the impact of the COVID19 outbreak on Cardiac patients admitted in the Intensive Care Unit of the Pitie-Salpetriere Hospital in Paris, France
This is observational study to assess the prognosis of patients hospitalized with COVID-19 confirmed by RT-PCR and exposed to trimethylxanthine (TMX). Trimethylxanthine is the active molecule present in coffee. Due to the lack of etiologic treatments and considering interest about old treatments as an avenue for research, we conducted a comparative study aiming to evaluate the effect of 1,3,7-trimethylxanthine on COVID-19 infected patients. This is actually a study about methodology. The objective of this study is therefore not to demonstrate the effect of the substance on the disease but the importance of a rigorous methodology in scientific research. This project is called "Method and Teaching of Scientific Studies".
Description: the patient clinical status at day 6 after hospital admission, defined as alive, or dead.
Measure: Comparison of vital status Time: 6 daysDescription: Evaluated by National Early Warning Score from 0 to 20, 20 being the worst score, with a high risk of death.
Measure: Comparaison of severity Time: 6 daysDescription: with
Measure: Comparaison of secondary effects (adverse events that needed disruption of treatment (anemia, tachycardia, osteoporosis) : secondary effects of coffee). Time: 6 daysThe purpose of this study is to define seroprevalence of anti-SARS-CoV2 among children of Hospital Workers in APHP, particularly exposed population, according to parents' SARS-CoV2 serological status.
Description: Percentage of children with seropositive according to parents' SARS Cov2 serological status
Measure: Seroprevalence of antibodies anti- SARS Cov2 in children of Hospital workers Time: at inclusionThe investigators hypothesize that detection of SARS-CoV2 on saliva samples will increase the performance of the screening program compared to the reference strategy (RT-PCR on a nasopharyngeal swab).
Description: RT-PCR on nasopharyngeal is considered as gold standard
Measure: Positivity of RT-PCR on nasopharyngeal swab for the SARS-CoV-2 virus Time: At diagnosisDescription: Number of samples tested in a day for each test
Measure: Practicability to samples Time: At diagnosisDescription: Quantity of premises required for each test
Measure: Practicability to premises Time: At diagnosisDescription: Feasibly Reading and interpretation For each test
Measure: Practicability to interpretation Time: At diagnosisDescription: Render times for each test
Measure: Practicability to render time Time: At diagnosisDescription: Research of IgG by ELISA and RDT
Measure: IgG Antibody detection in saliva Time: At diagnosisDescription: Research of IgM by ELISA and RDT
Measure: IgM Antibody detection in saliva Time: At diagnosisDescription: Research of IgA by ELISA and RDT
Measure: IgA Antibody detection in saliva Time: At diagnosisDescription: Evaluation by questionnaire of the patient tolerance of the salivary self-sampling compared to the nasopharyngeal swab (questions are about pain, discomfort, speed of performance)
Measure: Patient tolerance of the salivary self-sampling Time: At diagnosisDescription: Evaluation by questionnaire of the operator tolerance of the salivary self-sampling compared to the nasopharyngeal swab (questions is about pain, discomfort, speed of performance)
Measure: Operator tolerance of the salivary self-sampling Time: At diagnosisDescription: Including sampling, transport, technique (consumables, reagents, machine), human resources
Measure: Cost of each approach Time: At diagnosisMortality due to Covid-19 is much higher in the elderly. There are several reasons for the vulnerability of the elderly to the coronavirus: a less efficient immune system, underlying chronic conditions, less protected living conditions. They may also present a poor nutritional state and/or degraded metabolic reserves aggravating an underlying state of frailty. The prevalence of the risk of undernutrition in elderly patients with COVID-19 is high. The evolution of the nutritional status of people aged 70 years or older infected with SARS-Cov-2 is not yet well known. The prognosis of these patients could depend on their nutritional status at the time of the disease. In view of the lack of data, it would be interesting to compare the risk of mortality based on nutritional status in individuals with vs. those without COVID-19.
Alphabetical listing of all HPO terms. Navigate: Correlations Clinical Trials
Data processed on January 01, 2021.
An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.
Drug Reports MeSH Reports HPO Reports