|drug407||Baseline and during hospitalization blood samples Wiki||1.00|
There is one clinical trial.
The aim of the research is to study the immune checkpoint linked to the HLA-G molecule in the dysregulation of the control of COVID-19 infection.
Description: The CD3 + T lymphocyte cell populations (CD4 + ILT2 + and CD8 + ILT2 +) will be compared between the groups of patientsMeasure: Comparison of the percentage of T cells expressing the HLA-G receptor ILT2 (CD3+CD4+ILT2+ T cells, and CD3+CD8+ILT2+ T cells) between the 3 groups of patients. Time: 1 month
Description: Blood levels of soluble HLA-G and plasma microvesicles with expression of HLA-G will be compared between the groups of patients.Measure: Comparison of the expression of circulating soluble HLA-G, between the groups of patients. Time: 1 day
Description: Vital status collected 1 month post inclusion for all the patientsMeasure: 1 month survival Time: 1 month
Description: Comparison of the isoforms (alleles) of HLA-G regarding the severity of the disease for the infected patients.Measure: Assessment of the severity of the disease according to the isoform of HLA-G Time: 1 month
Description: The expression of the BSG cell receptor induced by HLA-G will be compared between COVID19 patients and uninfected patients.Measure: Comparison of the expression of one of the cell receptors of the SARS-CoV-2 virus, called BSG (Basigin), whose expression is modified by the interaction between HLA-G. Time: 1 day
Data processed on January 01, 2021.
An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.Drug Reports MeSH Reports HPO Reports