Developed by Shray Alag, The Harker School
Sections: Correlations,
Clinical Trials, and HPO
Navigate: Clinical Trials and HPO
Name (Synonyms) | Correlation |
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Name (Synonyms) | Correlation | |
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D012120 | Respiration Disorders NIH | 0.22 |
D001523 | Mental Disorders NIH | 0.22 |
D012140 | Respiratory Tract Diseases NIH | 0.20 |
Name (Synonyms) | Correlation |
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Navigate: Correlations HPO
There is one clinical trial.
Some COVID-19 survivors may have respiratory and mental health sequelae, especially those who required hospitalization. The investigators hypothesize that the participation of a rehabilitation program composite by home-based respiratory physiotherapy and telephone-based psychological support will improve respiratory function, quality of life, and psychological status in severe COVID-19 patients.
Description: Distance walked during 6-minutes (meters)
Measure: Six minute walk distance Time: Change from baseline measure at hospital discharge to week 6 and 12Description: The SGRQ scores from 0 (no impairment of quality of life by respiratory diseases/symptoms) to 100 (highest impairment of quality of life by respiratory diseases/symptoms)
Measure: Impact on overall health by respiratory diseases assessed by the score of the St. George's respiratory questionnaire (SGRQ) Time: Change from baseline measure at hospital discharge to week 6 and 12Description: The Patient Health Questionnaire-9 (PHQ-9) consists of nine items covering the Diagnostic and Statistical Manual of Mental Disorders-IV (DSM-IV) criteria for major depression scored on a four-point 0 (not at all) to 3 (almost every day) scale, with total scores ranging from 0 to 27. A greater score means worse depressive symptoms.
Measure: Depressive symptomatology assessed by the Patient Health Questionnaire (PHQ-9) Time: Change from baseline measure at hospital discharge to week 6 and 12Description: The Generalized Anxiety Disorder-7 (GAD-7) consists of seven items covering the DSM-IV criteria for GAD scored on a four-point 0 (not at all) to 3 (almost every day) scale, with total scores ranging from 0 to 21. A higher score means worse anxiety symptoms.
Measure: Anxious symptoms assessed by the Generalized Anxiety Disorder (GAD-7) questionnaire Time: Change from baseline measure at hospital discharge to week 6 and 12Description: The SF-36 questionnaire consists of 36 items, which are used to calculate eight subscales: physical functioning (PF), role physical (RP), bodily pain (BP), general health (GH), vitality (VT), social functioning (SF), role emotional (RE), and mental health (MH). The first four scores can be summed to create the physical composite score (PCS), while the last four can be summed to create the mental composite score (MCS). Scores for the SF-36 scales range between 0 and 100, with higher scores indicating a better health-related quality of life
Measure: Quality of life assessed by the Short Form Health Survey (SF-36) questionnaire Time: Change from baseline measure at hospital discharge to week 6 and 12Description: EQ-5D is a standardized tool for the assessment of quality of life in 5 different dimensions (Mobility, Self-Care, Usual Activities, Pain/Discomfort, Anxiety/Depression). Possible scores range from 1 (No problem) to 3 (Extreme problems) and each dimension are evaluated individually.
Measure: Quality of life assessed by the Health-Related Quality of Life (EQ-5D) questionnaire Time: Change from baseline measure at hospital discharge to week 6 and 12Description: Measured in milliliters by dynamic spirometry
Measure: Forced expiratory volume in the first second Time: Change from baseline measure at hospital discharge to week 6 and 12Description: Measured in milliliters by dynamic spirometry
Measure: Forced Vital Capacity Time: Change from baseline measure at hospital discharge to week 6 and 12Description: IES-R consists of 21 items covering the DSM-IV criteria for PTSD. Score varying from 0 (no risk of post traumatic stress) to 88 (highest risk of post traumatic stress).
Measure: Post-traumatic stress disorder symptomatology assessed by the Impact of Event Scale Revised (IES-R) questionnaire. Time: Change from baseline measure at hospital discharge to week 6 and 12Alphabetical listing of all HPO terms. Navigate: Correlations Clinical Trials
Data processed on January 01, 2021.
An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.
Drug Reports MeSH Reports HPO Reports