|D001172||Arthritis, Rheumatoid NIH||0.30|
There is one clinical trial.
This study will perform prospective repeated serological antibody testing on a cohort of at least 1000 healthcare workers at Great Ormond Street Hospital. Within this cohort, a subset of 150-250 staff members with confirmed (PCR positive) SARS-CoV-2 disease will be followed with intensive monthly testing for 6 months to determine whether antibody levels in the blood are maintained or decrease during this time. All 1000 recruited healthcare workers will be followed 6-monthly
Description: To determine the kinetics (rate of change) of SARS-CoV-2 nucleo-capsid protein antibody titres in proven cases of SARS-CoV-2 over the 6 month period following infectionMeasure: Change in serial monthly log-transformed antibody titre levels as measured Time: 6 months period post infection
Description: To determine the proportion of completely asymptomatic healthcare workers who have evidence of SARS-CoV-2 antibodies in their serum indicative of past infectionMeasure: Proportion of completely asymptomatic healthcare workers with evidence of SARS-CoV-2 antibodies Time: 12 months
Description: To determine the attack rate of SARS-CoV-2 in healthcare workers who have antibodies versus those who do not have antibodiesMeasure: The attack rate of SARS-CoV-2 in healthcare workers who have antibodies compared to those who do not Time: Betwen 3 to 6 years
Description: To determine the immune correlates of protection (Antibody Titres sufficient for protection) against future exposure to SARS-CoV-2Measure: The immune correlates of protection against future exposure to SARS-CoV-2 Time: Between 3 to 6 years
Data processed on January 01, 2021.
An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.Drug Reports MeSH Reports HPO Reports