|D008107||Liver Diseases NIH||0.35|
|D003920||Diabetes Mellitus, NIH||0.20|
There is one clinical trial.
This study is carried on in Wuchang Hospital in Wuhan, China. The investigators plan to recruit 80 patients with COVID-19 and 80 matched healthy control. Using the design of case-control study, the study aims to assess the neurocognitive functions such as executive function and attentional bias in recovered patients with COVID-19 under normal and stress conditions, and to analyze the influencing factors of neurocognitive functions, such as mental health conditions, inflammation indicators and cardiopulmonary function.
Description: assessed by the n-back task, including 0-back, 1-back and 2-backMeasure: working memory Time: 10 minutes
Description: assessed by the trail-making taskMeasure: Cognitive flexibility Time: 3 minutes
Description: assessed by the stroop taskMeasure: Inhibitory control Time: 10 minutes
Description: assessed by the dot-probe taskMeasure: Attention Bias Time: 15 minutes
Description: Concentration of serum TNFalpha in ng/ml will be assessed by ELISAMeasure: Serum TNFalpha Time: 1 day
Description: Concentration of serum IL-6 in ng/ml will be assessed by ELISA.Measure: Serum IL-6 Time: 1 day
Description: hypersensitive C-reactive protein(hs-CRP) in mg/L will be assessed by Turbidimetric inhibition immuno assay.Measure: CRP Time: 1 day
Description: assessed by Self-Rating Depression Scale, which is consist of 20 items scoring 1 to 4.Measure: Depression Time: 3-5 minutes
Description: assessed by Self-Rating Anxiety Scale, which is consist of 20 items scoring 1 to 4.Measure: Anxiety Time: 3-5 minutes
Description: assessed by PTSD Checklist for DSM-5 (PCL-5)Measure: PTSD Time: 3-5 minutes
Description: assessed by Pittsburgh sleep quality index (PSQI)Measure: Sleep Time: 3-5 minutes
Description: assessed by Montreal - Cognitive Assessment (MoCA)Measure: General cognition Time: 8-10 minutes
Description: maximal inspiration pressure（MIP), maximal expiration pressure（MEP）Measure: Cardiopulmonary function 1 Time: 15 minutes
Description: Assessed by the 6-minutes' walk testMeasure: Cardiopulmonary function 2 Time: 10 minutes
Description: concentration of saliva cortisol stress, assessed by ELISAMeasure: Stress response indicator 1 Time: Saliva samples will be colleted before stress, 0 minutes and 10 minutes after stress.
Description: Hear ratesMeasure: Stress response indicator 2 Time: Assessed before and 0 minute after stress
Description: Blood pressure before stress and after stressMeasure: Stress response indicator 3 Time: Assessed before and 0 minute after stress
Data processed on January 01, 2021.
An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.Drug Reports MeSH Reports HPO Reports