SNPMiner Trials (Home Page)
Report for Mutation G276T
Developed by Shray Alag, 2020.
SNP Clinical Trial Gene
There is one clinical trial.
Clinical Trials
1 Hypocaloric Diet With or Without Microencapsulated Fish Oil or Conjugated Linoleic Acid on Oxidative Stress and Cardiovascular Risk Factors in Women With Metabolic Syndrome Genotyped for Polymorphisms in the Genes PPAR Gamma 2 (Pro12Ala) and Adiponectin (G276T)
Our aim was to assess the effects of a hypocaloric diet, including diet fruit jelly with microencapsulated fish oil or conjugated linoleic acid or placebo, on anthropometry, body composition, insulin resistance and lipid profile in women with metabolic syndrome and genotype Pro12Pro in the PPAR gamma 2 gene.
NCT02183922 Insulin Resistance Oxidative Stress Lipid Profile Blood Pressure Anthropometric Measure Dietary Supplement: microencapsulated conjugated linoleic acid Dietary Supplement: microencapsulated fish oil Dietary Supplement: light fruit jam MeSH:Metabolic Syndrome Insulin Resistance
HPO:Insulin resistance
Hypocaloric Diet With or Without Microencapsulated Fish Oil or Conjugated Linoleic Acid on Oxidative Stress and Cardiovascular Risk Factors in Women With Metabolic Syndrome Genotyped for Polymorphisms in the Genes PPAR Gamma 2 (Pro12Ala) and Adiponectin (G276T). --- Pro12Ala --- --- G276T ---
Primary Outcomes
Description: Plasma malondialdehyde levels
Measure: Oxidative stress biomarker Time: Change from baseline at 12 weeksSecondary Outcomes
Description: Homeostatic Model Assessment-Insulin Resistance index, adiponectin, glucose and insulin levels
Measure: Insulin resistance Time: Change from baseline at 12 weeksDescription: Total cholesterol, LDL-cholesterol, VLDL-cholesterol, HDL-cholesterol and triglycerides serum levels and EPA, DHA and total conjugated linoleic acid plasma levels
Measure: Lipid profile Time: Change from baseline at 12 weeksDescription: Body weight, body mass index and waist circumference
Measure: Anthropometric measures Time: Change from baseline at 12 weeksDescription: Fat-free mass and fat mass
Measure: Body composition measures Time: Change from baseline at 12 weeksDescription: Systolic blood pressure and diastolic blood pressure
Measure: Blood pressure Time: Change from baseline at 12 weeks