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Clinical Trials

1 Consecutive, Case Control Study of Association Between Single Nucleotide Polymorphism of SP-D and Susceptibility and Prognosis of Infectious Keratitis

This study explores the association between single nucleotide polymorphism (Met11Thr) of surfactant protein D(SP-D) and susceptibility and prognosis of infectious keratitis.Met11Thr of SP-D of patients with keratitis and normal controls were compared.Allele and genotype frequencies of patients with keratitis and normal controls were determined by polymerase chain reaction with sequence specific primers(PCR-SSPs) .SP-D gene polymorphism of patients with keratitis and normal controls was detected by Sanger sequencing

NCT04213313 Infectious Keratitis Drug: Treatment of bacterial keratitis Drug: Treatment of fungal keratitis Drug: Treatment of viral keratitis Diagnostic Test: corneal scraping Other: Sequencing

MeSH:Communicable Diseases Infection Keratitis

HPO:Keratitis

Association Between SNP of SP-D and Susceptibility and Prognosis of Infectious Keratitis This study explores the association between single nucleotide polymorphism (Met11Thr) of surfactant protein D(SP-D) and susceptibility and prognosis of infectious keratitis.Met11Thr of SP-D of patients with keratitis and normal controls were compared.Allele and genotype frequencies of patients with keratitis and normal controls were determined by polymerase chain reaction with sequence specific primers(PCR-SSPs) .SP-D gene polymorphism of patients with keratitis and normal controls was detected by Sanger sequencing Base type. --- Met11Thr ---

HPO Nodes