SNPMiner Trials (Home Page)
Report for Mutation P300D
Developed by Shray Alag, 2020.
SNP Clinical Trial Gene
There is one clinical trial.
Clinical Trials
1 Analysis of Patient Ventilator Asynchrony Using Electrical Impedance Tomography (EIT) in Patients With Acute Respiratory Failure
Patient-ventilator asynchrony is an important clinical issue in mechanically ventilated patients. For patients with moderate to severe acute respiratory distress syndrome (ARDS), various types of patient ventilator asynchrony may lead to injury of the lung. For example, double cycling may lead to high tidal volume and pendelluft may result in transient overstretch of dependent lung region. In this project, the investigators will record and analyze various types of patient-ventilator asynchrony in ARDS patients and analyze the regional distribution of lung gas and determined their harmful effect via concomitant recording of EIT and transpulmonary pressure. The results may influence our ventilator management of ARDS patients.
NCT04442815 ARDS, Human MeSH:Respiratory Distress Syndrome, Adult
Airway pressure and esophageal pressure will be measured using differential pressure transducers (P300D, Validyne Corp., Northridge, CA.). --- P300D ---
Primary Outcomes
Description: Various types of patient ventilator asynchrony
Measure: Patient ventilator asynchrony Time: up to 1 hour following interruption of muscle relaxantDescription: Regional ventilation distribution by EIT in various types of patient ventilator asynchrony
Measure: Regional ventilation distribution by EIT Time: up to 1 hour following interruption of muscle relaxantSecondary Outcomes
Description: duration of hospitalization and hospital mortality
Measure: hospitalization day and final outcome Time: up to 3 months