CovidResearchTrials by Shray Alag


CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)


Taste and olfactory function evaluationWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (1)


Name (Synonyms) Correlation
drug739 Nasal swab Wiki 0.71

Correlated MeSH Terms (2)


Name (Synonyms) Correlation
D045169 Severe Acute Respiratory Syndrome NIH 0.06
D018352 Coronavirus Infections NIH 0.05

Correlated HPO Terms (0)


Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials


1 Study of the Pathogenesis of Olfactory Disorders in COVID-19

This study is a case-control study to characterize the molecular and cellular anomalies of the olfactory epithelium of COVID-19 patients with isolated anosmia, by comparison with the olfactory epithelium of non-infected subjects.

NCT04366934 Coronavirus Infection Severe Acute Respiratory Syndrome Sars-CoV2 Other: Nasal swab Other: Taste and olfactory function evaluation
MeSH:Coronavirus Infections Severe Acute Respiratory Syndrome

Primary Outcomes

Description: Ratio of olfactory sensory cells in the nasal cytological sample

Measure: Molecular and cellular defects in olfactory epithelium

Time: 30 months

Secondary Outcomes

Description: Multiple measurements will be analyzed to characterize the immune and inflamatory status of the olfactory mucosa (presence of infiltrated immune cells, activation state of the immune cells in the epithelium, cytokine and interleukin level)

Measure: Biological mechanisms involved in the pathogenesis of the disease

Time: 30 months

Description: Demographic variables (sex, age, blood type), risk factors (tobacco, overweight, diabetes, rhinosinusitis disease, respiratory allergy)

Measure: Epidemiological characteristics

Time: 30 months

Description: Self-questionnaire taste and smell survey (TTS)

Measure: Olfactory and taste dysfunction

Time: 30 months

Description: Visual analogue scale (VAS) (units from 0 normal perception to 100 no perception)

Measure: Olfactory and taste dysfunction

Time: 30 months


No related HPO nodes (Using clinical trials)