|drug1231||Vitamin D Wiki||0.50|
|drug1230||Vitamin C Wiki||0.41|
|D003141||Communicable Diseases NIH||0.11|
|D045169||Severe Acute Respiratory Syndrome NIH||0.06|
|D018352||Coronavirus Infections NIH||0.05|
There is one clinical trial.
One case of maternal-fetal transmission of SARS Cov-2 was published (1). Ig M and Ig G were found at two hours after birth of a new born from a mother COVID-19. Another study on few newborns COVID-19 reported that the SARS-Cov-2 was not transmitted in utero but only after birth. Although there are few data on COVID-19 during pregnancy, according to our national data collections, it appears to be responsible for miscarriages and fetal deaths. There are also intrauterine growth restrictions and an increase of the rate of cesarean sections for maternal indications. Therefore, it is essential to know if there is a maternal viremia which infects the fetus because the consequences in terms of management would be completely different. In fact, the potential intrauterine infection will lead to antenatal monitoring of these patients with an antenatal diagnosis and may be a treatment. Therefore, it seems essential to explore the mode of transmission to the newborn since many newborns have COVID-19 infection We will propose to all pregnant women SARS- Cov-2 positive to perform PCR SARS-Cov-2 tests and /or serology's (IgM and Ig G) on the amniotic fluid, the blood cord and the placenta.
Description: COVID-19 by positive PCR in cord blood and / or positive serologiesMeasure: COVID-19 by positive PCR in cord blood and / or positive serologies Time: Day 0
Description: COVID-19 by positive PCR in amniotic fluid and placentaMeasure: COVID-19 by positive PCR in amniotic fluid and placenta Time: Day 0
Description: Newborn baby infected with COVID-19 on gastric tubing, rectal sample, nasopharyngeal samples by COVID-19 PCR and blood samples by serologyMeasure: New born infected by COVID-19 Time: Day 0