Name (Synonyms) | Correlation | |
---|---|---|
drug852 | Placebo + Placebo Wiki | 0.71 |
drug509 | Hydroxychloroquine + Placebo Wiki | 0.71 |
drug131 | BNT162b1 Wiki | 0.50 |
drug133 | BNT162c2 Wiki | 0.50 |
drug130 | BNT162a1 Wiki | 0.50 |
drug132 | BNT162b2 Wiki | 0.50 |
drug505 | Hydroxychloroquine Wiki | 0.08 |
Name (Synonyms) | Correlation | |
---|---|---|
D012327 | RNA Virus Infections NIH | 0.35 |
D012141 | Respiratory Tract Infections NIH | 0.16 |
D003141 | Communicable Diseases NIH | 0.15 |
D007239 | Infection NIH | 0.10 |
D014777 | Virus Diseases NIH | 0.10 |
D045169 | Severe Acute Respiratory Syndrome NIH | 0.04 |
D018352 | Coronavirus Infections NIH | 0.03 |
Name (Synonyms) | Correlation | |
---|---|---|
HP:0011947 | Respiratory tract infection HPO | 0.16 |
There are 2 clinical trials
Q-PROTECT is a placebo controlled randomized trial (RCT) to ascertain the efficacy of hydroxychloroquine (HC) alone or, in combination with azithromycin (AZ), in reducing viral load in patients with COVID 19.
Description: Days
Measure: Proportion of virologically cured (no virus detected) cases at day 6 Time: Day 6Description: Days
Measure: The dichotomous virologic shedding endpoint as assessed at two weeks after study entry Time: 2 weeksDescription: Days
Measure: Quantitative viral load (assessed with each virology testing set) Time: Day 1 to 21COVID-19 is an emerging pandemic disease affecting most countries including Senegal, caused by the new coronavirus (SARS-CoV-2) which was first detected in the city of Wuhan in China in December 2019. A rapid spread of the disease has occurred at a global scale, associated with a mortality rate of 3.4%. The first case in Africa was declared on February 15, 2020 in Egypt and the first case in Senegal was declared on March 2nd, 2020. In this context, the SEN-CoV-Fadj clinical trial aims to evaluate efficacy and safety, among adults, of different therapeutic regimens considered optimal according to current knowledge, as well as available and adapted to Sub-Saharan Africa. This trial is nested into a cohort of confirmed cases of COVID-19 in Senegal aiming to understand the main clinical, biological, virologic and immunological characteristics of the infection. The protocol of the cohort is based and adapted from the International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC) / World Health Organization (WHO) Clinical Characterisation Protocol (CCP). Two therapeutic regimens have been eligible in the short term for SEN-CoV-Fadj: Hydroxychloroquine (HCQ) on one hand, and the combination of Hydroxychloroquine and Azithromycin (HCQ + AZM) on the other hand.
Description: Real time-PCR (RT-PCR) result of the naso- and oro-pharyngeal sample
Measure: SARS-CoV-2 viral load level Time: Day 7